Zycolchin 05 Mg Tablet 10

Zycolchin Tablet 10

Zydus Cadila

Strip of 10 Units

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MRP ~~₹36.51~~

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Composition

Colchicine (0.5 Mg)

Zycolchin Tablet is generally used to manage the symptoms of gout. This medicine belongs to a class of medications known as anti-inflammatory agents.

Besides gout, this medicine can also be used in managing Familial Mediterranean Fever (FMF), an inherited condition that results in recurrent episodes of fever and inflammation in different parts of the body. It's important to remember that this tablet has various uses, all aimed towards reducing inflammation and managing pain.

Before you start taking this medicine, consult your doctor about the correct dosage and frequency. Disclose any pre-existing conditions or ongoing medications to your doctor before starting this medicine. If you experience any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Zycolchin Tablet is used for the following:

Management and prevention of gout flares in adults.
Handling Familial Mediterranean Fever (FMF) in adults and children aged 4 years or older.

Directions for Use of Zycolchin Tablet 10

Here's how you should take the Zycolchin Tablet:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Zycolchin Tablet is taken orally.

Zycolchin Tablet may have the following side effects:

Diarrhoea
Nausea
Vomiting
Abdominal pain
Muscle pain or weakness
Numbness or tingling in fingers or toes
Unusual bruising or bleeding: This means you may notice marks on your skin that aren't linked to known injuries, or you may bleed more easily than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zycolchin Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Drink plenty of healthy fluids to stay hydrated and follow the diet recommended by your doctor.
Nausea: Follow the dietary recommendations provided by your doctor.

Zycolchin Tablet contains colchicine (0.5 mg) which works on the body as follows:

Inhibits Neutrophil Migration: Colchicine effectively reduces inflammation by blocking the activity of white blood cells called neutrophils.
Reduces Accumulation of Inflammatory Cells: By preventing these cells from reaching areas affected by gout or FMF, it helps alleviate inflammation, swelling, and pain associated with these conditions.

Pregnancy

If you are pregnant, caution is advised while taking Zycolchin Tablet. It is best to consult your doctor before taking this medicine.

Breastfeeding

Likewise, if you're breastfeeding, it's crucial to approach Zycolchin Tablet with caution. You should discuss this with your doctor before starting the medication.

Alcohol

Alcohol can potentially interact with Zycolchin Tablet. Always remember to discuss your drinking habits with your doctor.

Liver

For those with mild to moderate liver impairment, it's advisable to exercise caution when using Zycolchin Tablet. If you have severe liver disease, this medicine may not be suitable; please consult your doctor.

Kidney

If you have a history of kidney problems, it's important to be cautious before taking Zycolchin Tablet. Consulting your doctor before starting this medicine would be a wise step.

Using Machines & Driving

Zycolchin Tablet may affect your ability to operate machinery or drive. Thus, caution is advised until you know how this medicine affects you.

Allergy

Be mindful if you've shown hypersensitivity towards colchicine or any other ingredients in Zycolchin Tablet. If so, using this medicine might not be right for you.

Children

Caution is advised while giving Zycolchin Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zycolchin Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zycolchin Tablet interacts with the following medicines:

CYP3A4 inhibitors: Medicines like clarithromycin, itraconazole, and ketoconazole can lead to increased colchicine levels and toxicity when taken with Zycolchin Tablet.
P-glycoprotein inhibitors: Medications such as cyclosporine and verapamil can increase colchicine exposure when used concurrently with Zycolchin Tablet.
Statins: There's an increased risk of muscle weakness and breakdown (myopathy and rhabdomyolysis) when statins like simvastatin are taken with Zycolchin Tablet.

Drug-Food Interactions

There are no specific food interactions with Zycolchin Tablet.

Drug-Disease Interactions

Zycolchin Tablet interacts with the following diseases:

Kidney disease: Those with kidney problems should be careful when taking Zycolchin Tablet as this medicine could worsen your condition.
Liver disease: If you have liver disease, be cautious while taking Zycolchin Tablet as it might exacerbate your condition.
Blood disorders: Patients suffering from blood disorders should monitor their blood counts regularly while taking Zycolchin Tablet since it may cause bone marrow suppression.

Daily Dose

For managing your condition effectively, it's essential to take Zycolchin Tablet as advised by your doctor. The dosage might differ based on the severity of your condition and how you respond to the medicine. Always adhere strictly to the prescribed dosage and never modify it without consulting your doctor.

Over Dose

If you accidentally take more Zycolchin Tablet than prescribed, you might experience common side effects such as stomach upset or diarrhoea. Avoid panicking, but do inform your doctor about this situation so they can provide guidance.

Missed Dose

Should you forget to take your Zycolchin Tablet dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take an extra dose without asking your doctor first.

Keep Zycolchin Tablet in its original packaging to protect it from light and moisture.
Store the medicine at room temperature, ideally below 30°C.
Make sure to keep this medicine out of reach of children.
Always check the expiry date before using Zycolchin Tablet.

To manage gout, you might find it beneficial to limit your intake of high-purine foods. These include red meat, shellfish, and alcohol.
Staying well-hydrated by drinking plenty of water can help prevent uric acid crystals from forming in your joints, which is a leading cause of gout pain.

Fact Box

Drug Category	Anti-inflammatory Alkaloid
Therapeutic Category	Anti-gout
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gout, Familial Mediterranean Fever

What Is Zycolchin Tablet used for?

Zycolchin Tablet is primarily used to manage gout flares and Familial Mediterranean Fever, and conditions involving inflammation, swelling, and pain.

How does Zycolchin Tablet work?

Zycolchin Tablet contains colchicine, which reduces inflammation by inhibiting the activity of certain white blood cells involved in the inflammatory process.

Can I take Zycolchin Tablet with food?

You must take the medicine exactly as prescribed by your doctor.

What precautions should I take while using Zycolchin Tablet?

Patients with mild to severe kidney or liver problems, blood disorders, or known sensitivity to colchicine should use this medicine with caution after consulting their doctor.

Are there any medicines that interact with Zycolchin Tablet?

Yes, medicines like clarithromycin, itraconazole, ketoconazole, cyclosporine and others can interact with Zycolchin Tablet. Always inform your doctor about all medications you're taking.

What are some common side effects of Zycolchin Tablet?

Common side effects include stomach issues such as diarrhoea, nausea and vomiting. Less common effects include muscle pain or weakness, numbness or tingling in extremities.

How should I store Zycolchin Tablet?

Store Zycolchin Tablet at room temperature, away from light and moisture. Keep it in its original packaging out of reach of children.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

5V74+4P2, Jay Prakash Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Takeda Pharmaceuticals America, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022352s017lbl.pdf
AGEPHA Pharma FZ LLC. (2023). LODOCO (colchicine) tablets, for oral use [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215727s000lbl.pdf
Mutual Pharmaceutical Company, Inc. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022351lbl.pdf
Romeg Therapeutics, LLC. (2019). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210942s000lbl.pdf
Sadiq, N. M., Robinson, K. J., & Terrell, J. M. (2023, May 29). Colchicine. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK431102/
Colchicine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01394

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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