Z Sar A Tablet 10

Corazon Pharma Pvt Ltd

Strip of 10 Units

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MRP ~~₹54~~

₹44.28

₹5.40/Units

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Composition

Amlodipine (5 Mg) + Losartan (50 Mg)

Z Sar A Tablet 10 is primarily used for managing hypertension, also known as high blood pressure. This medicine is a combination formulation from the class of medications called antihypertensives.

Additionally, this medicine can also help reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, a condition where the heart muscle becomes thickened. This medicine also assists in slowing the progression of kidney disease in individuals who have type 2 diabetes and high blood pressure.

Before starting this medicine, it is crucial to consult your doctor to understand the right dosage and frequency. Inform your doctor about any pre-existing illnesses or ongoing medicines you are taking. If you notice any side effects while on this medication, promptly notify your doctor. Make sure to continue taking the medicine for the duration prescribed by your doctor for effective results.

Z Sar A Tablet 10 is used for the following:

Managing high blood pressure in adults
Providing better control of blood pressure by combining amlodipine and losartan
Reducing the risk of stroke in patients with high blood pressure and thickened heart muscle
Slowing the progression of kidney disease in patients suffering from type 2 diabetes and high blood pressure

Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
Try to take this medicine at the same time each day.
Do not stop taking this medicine abruptly. If you are considering stopping the tablet, consult your doctor first.

Z Sar A Tablet 10 is taken orally.

The following common side effects may be experienced upon taking Z Sar A Tablet 10:

Headache
Dizziness
Fatigue
Ankle swelling (oedema)
Nausea
Abdominal pain
Increased potassium levels in the blood (hyperkalaemia)

Managing the Side Effects:

Most side effects are temporary, generally harmless, and resolve upon discontinuing the use of Z Sar A Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage certain common side effects:

Dizziness: If this tablet makes you dizzy, consider taking this medicine at bedtime.
Abdominal pain: Try taking Z Sar A Tablet 10 with a meal to lessen this effect.

Z Sar A Tablet 10 has two active ingredients that work together to help manage high blood pressure:

Losartan (50 mg): As an angiotensin II receptor blocker, losartan works by blocking the action of angiotensin II, a hormone that causes your blood vessels to constrict or narrow. By inhibiting this hormone, losartan aids in widening your blood vessels, which leads to a reduction in blood pressure.
Amlodipine (5 mg): This ingredient is a calcium channel blocker that functions by relaxing your blood vessels. When your blood vessels are relaxed, it makes it easier for your heart to pump blood around your body, lowering your blood pressure.

Pregnancy

Z Sar A Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Z Sar A Tablet 10 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Drinking alcohol while taking Z Sar A Tablet 10 might increase the risk of side effects like dizziness and fainting. So, it's a good idea to limit your alcohol intake while on this medication.

Liver

Caution is advised while taking Z Sar A Tablet 10 if you have liver problems. This medicine may affect liver function, so discuss your liver health with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, caution is advised before using Z Sar A Tablet 10. Consult your doctor for advice.

Using Machines & Driving

Z Sar A Tablet 10 can cause dizziness, especially during the first few days of treatment. Exercise caution while driving or operating machinery until you know how this medicine affects you.

Allergy

If you're allergic to amlodipine, losartan, or any other ingredients in Z Sar A Tablet 10, avoid taking this medication. Always inform your doctor about any previous allergic reactions to medications.

Children

Z Sar A Tablet 10 is not recommended for use in children under 18 years of age. Always consult a doctor before giving any medicine to a child.

Older Patients

Older patients should take Z Sar A Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Z Sar A Tablet 10 interacts with the following medicines:

Potassium-sparing diuretics: Medicines, like spironolactone and eplerenone, when used together with Z Sar A Tablet 10, can lead to an excessive increase in your blood potassium levels (hyperkalaemia).
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines such as ibuprofen and naproxen may reduce the blood pressure-lowering effect of Losartan in Z Sar A Tablet 10.
Statins: Amlodipine in Z Sar A Tablet 10 can raise levels of statins like simvastatin, increasing the risk of muscle toxicity.

Drug-Food Interactions

Z Sar A Tablet 10 interacts with the following foods:

Grapefruit juice: It may increase the levels of amlodipine, enhancing its effects.

Drug-Disease Interactions

Z Sar A Tablet 10 interacts with the following diseases:

Liver disease: If you have liver disease, use this medicine with caution, as it might worsen your condition.
Kidney impairment: In patients with kidney problems, this medication should be used cautiously, as dose adjustments may be necessary.

Daily Dose

Your doctor will prescribe the recommended dose of Z Sar A Tablet 10 based on factors like the severity of your condition and how you respond to the medicine. Always stick to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

Taking too many Z Sar A Tablet 10 might lead to common side effects such as dizziness, headache, or fatigue. If you have taken too much of this medicine, inform your doctor.

Missed Dose

If you forget to take a dose of Z Sar A Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Don't increase your dose without talking to your doctor.

Store Z Sar A Tablet 10 at room temperature.
Keep the medicine in a dry place, shielded from light and moisture.
Be sure to keep the medicine out of the reach of children.
Always ensure that you are using the medicine before its expiration date.

Maintain a diet low in salt to support blood pressure management. This helps Z Sar A Tablet 10 work more effectively in controlling hypertension.
Regular physical activity is beneficial, as it can lower blood pressure and reduce the risk of heart-related health issues. Always consult your doctor about the type and intensity of exercise suitable for you.

Fact Box

Drug Category	Calcium Channel Blocker, Angiotensin II Receptor Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Kidney Disease in Type 2 Diabetes, Left Ventricular Hypertrophy

What is the main use of Z Sar A Tablet 10?

Z Sar A Tablet 10 is used primarily to manage high blood pressure, known as hypertension.

How does Z Sar A Tablet 10 work?

Z Sar A Tablet 10 contains amlodipine and losartan, which relax and widen blood vessels, respectively, reducing blood pressure.

What should I do if I miss a dose of Z Sar A Tablet 10?

If you miss a dose, take it as soon as you remember. Skip it if it's nearly time for the next dose.

Can I stop taking Z Sar A Tablet 10 once my blood pressure normalises?

No. Regularly taking your prescribed medicine maintains healthy blood pressure levels. Do not stop the tablet without consulting your doctor first.

Is it safe to take Z Sar A Tablet 10 during pregnancy?

No, Z Sar A Tablet 10 is not recommended during pregnancy. If you're pregnant or planning to be, inform your doctor.

How long does it take for Z Sar A Tablet 10 to start working?

Its effect is gradual, and full benefits may be seen after a few weeks. Some may notice improvement within one week.

Are there any lifestyle changes I should consider while taking Z Sar A Tablet 10?

Yes, adopting a healthy diet low in salt and fat, regular exercise, managing stress, quitting smoking, and moderating alcohol can help.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Sonmur Apartments, S. V Road, Malad (W), Near Marve Road Junction, Mumbai – 400 064, Maharashtra, India.

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2011, May). Norvasc (amlodipine) label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf
U.S. Food and Drug Administration. (2018, Oct). Cozaar (losartan) tablets label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020386s062lbl.pdf
U.K. National Health Service. (n.d.). Amlodipine. https://www.nhs.uk/medicines/amlodipine/
U.S. National Library of Medicine. (2018, Feb 15). Losartan – MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a695008.html
U.S. National Library of Medicine. (2018, Feb 15). Amlodipine – MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a692044.html
DrugBank Online. (2024, Jun 13). Losartan. https://go.drugbank.com/drugs/DB00678
DrugBank Online. (2024, Jun 13). Amlodipine. https://go.drugbank.com/drugs/DB00381

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