Z Rano 500 Sr Tablet 10

Azurite Bioscience Pvt Ltd

Strip of 10 Units

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Composition

Ranolazine (500 Mg)

Z Rano 500 Sr Tablet 10 is primarily used to manage chronic stable angina, a condition characterised by chest pain due to reduced blood supply to the heart. This medication falls under the category of anti-anginal agents.

This tablet is also used when other anti-anginal medicines like beta-blockers or calcium channel blockers are insufficient in controlling symptoms. It enhances blood flow to the heart muscle, thereby preventing angina attacks.

Before you start taking this medicine, it's essential to consult your doctor about the correct dosage and frequency. Your doctor needs to know about any ongoing medications or pre-existing conditions you may have. If you experience any side effects while on this medicine, inform your doctor immediately. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

Z Rano 500 Sr Tablet 10 is used for the following:

Management of chronic stable angina pectoris: This condition occurs when your heart muscle doesn't receive enough oxygen-rich blood, causing chest pain or discomfort.

Directions for Use of Z Rano 500 Sr Tablet 10

Swallow the tablet whole with a glass of water.
Avoid crushing, breaking, or chewing the tablet.
Ensure you do not take more than the recommended dose without consulting your doctor.
Even if symptoms are not bothersome, continue to take this medicine regularly as prescribed for optimal results.
Lastly, it's crucial not to stop taking Z Rano 500 Sr Tablet 10 without speaking to your doctor first.

Z Rano 500 Sr Tablet 10 is taken orally.

Z Rano 500 Sr Tablet 10 may have the following side effects:

Dizziness
Headache
Constipation
Nausea
Fainting: This is a sudden loss of consciousness, usually temporary.
Mental Confusion: This refers to a state where you might feel disoriented or unclear in your thinking.
Irregular Heartbeat: Also known as arrhythmia, it's when your heart doesn't beat normally.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Z Rano 500 Sr Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Z Rano 500 Sr Tablet 10 with food or milk to lessen this effect.
Dizziness: Consider taking this medicine at night if it causes dizziness during the day.

Z Rano 500 Sr Tablet 10 contains ranolazine (500 mg), which acts on the body in the following ways:

Reduces Sodium Current: Ranolazine reduces the late sodium current in heart muscle cells, minimising the build-up of sodium within these cells.
Decreases Calcium Overload: By reducing intracellular sodium accumulation, ranolazine indirectly decreases calcium overload in heart muscle cells.
Improves Myocardial Relaxation: Ranolazine promotes better relaxation of myocardial cells (heart muscle cells) by maintaining ionic balance.
Reduces Left Ventricular Stiffness: By improving myocardial relaxation, ranolazine decreases left ventricular stiffness, which is a part of your heart's main pumping chamber. This makes it easier for your heart to pump blood, thus reducing the risk of angina attacks.

Pregnancy

Caution is advised when taking the Z Rano 500 Sr Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The safety and efficacy of Z Rano 500 Sr Tablet 10 in nursing mothers have not been established. It's advisable to discuss this with your doctor before starting this medication.

Alcohol

There's limited data on the interaction of Z Rano 500 Sr Tablet 10 with alcohol. Nonetheless, caution is advised when consuming alcohol while on this medication. It's sensible to consult your doctor for guidance.

Liver

Z Rano 500 Sr Tablet 10 should be used cautiously in patients with liver impairment. If you have any liver health issues, it's wise to discuss them with your doctor before beginning this medication.

Kidney

If you have a history of kidney problems, it's prudent to consult your doctor before starting Z Rano 500 Sr Tablet 10.

Using Machines & Driving

Z Rano 500 Sr Tablet 10 may cause dizziness, a common side effect. If you experience this, avoid driving or operating heavy machinery until you feel normal again.

Allergy

This medicine is not suitable for patients allergic to ranolazine or any other ingredients in the tablet. If you have known allergies, inform your doctor before starting this medication.

Children

The safety and efficacy of Z Rano 500 Sr Tablet 10 in children under 18 years have not been established. It should only be used if potential benefits justify the risks.

Older Patients

Older patients should take Z Rano 500 Sr Tablet 10 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Z Rano 500 Sr Tablet 10 interacts with the following medicines:

Strong CYP3A Inhibitors: Medicines such as ketoconazole, clarithromycin, and ritonavir can significantly increase the concentration of ranolazine in your blood, which may lead to increased side effects.
Moderate CYP3A Inhibitors: Medicines like diltiazem, verapamil, and certain antibiotics can also raise the levels of ranolazine in your bloodstream.
P-glycoprotein Transported Medications: Taking Z Rano 500 Sr Tablet 10 with medicines like digoxin can increase the latter's levels in your body.

Drug-Food Interactions

Certain foods can interact with Z Rano 500 Sr Tablet 10:

Grapefruit Products: These should be avoided as they can increase the ranolazine levels in your body.

Drug-Disease Interactions

Z Rano 500 Sr Tablet 10 interacts with the following diseases:

Liver Impairment: Patients with liver issues should use this medicine cautiously as it may exacerbate their condition.
Kidney Impairment: Those with kidney problems should also exercise caution while taking this medication.
QT Prolongation: This medicine should be used carefully by those with pre-existing QT prolongation due to the risk of further elongating the QT interval.

Daily Dose

Take your daily recommended dose of Z Rano 500 Sr Tablet 10 as your doctor prescribes. This can vary depending on the severity of your condition and your response to the medicine.

Over Dose

If you accidentally take too much Z Rano 500 Sr Tablet 10, common overdose symptoms might include feeling dizzy or having a headache. If such symptoms persist, consult your doctor.

Missed Dose

If you forgot to take your Z Rano 500 Sr Tablet 10, take it as soon as you remember. If it's almost time for the next dose, skip the missed one. Always consult your doctor before making any changes to your dosage plan.

Store Z Rano 500 Sr Tablet 10 in a cool, dry place below 30°C.
Protect the tablets from moisture and heat.
Always keep the medicine out of children's reach for safety.
Use the medicine before its expiry date, as mentioned on the packaging.

Since Z Rano 500 Sr Tablet 10 is used to manage angina, try adopting a heart-friendly diet. Reduce saturated fats and include more fruits, vegetables, and whole grains.
Regular physical activity can also help. Begin with light activities like walking or cycling, but consult your doctor before starting any new exercise routine.

Fact Box

Drug Category	Late Sodium Current Reduction
Therapeutic Category	Anti-Anginal Agents
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Stable Angina Pectoris

What is Z Rano 500 Sr Tablet 10 used for?

Z Rano 500 Sr Tablet 10 is prescribed to manage chronic stable angina, a type of chest pain caused by reduced blood flow to the heart.

How does Z Rano 500 Sr Tablet 10 work?

Z Rano 500 Sr Tablet 10 reduces sodium and calcium overload in heart cells, improves heart function and reduces oxygen demand, thus managing angina symptoms.

Can I take Z Rano 500 Sr Tablet 10 while on other anti-anginal medicines?

Yes, Z Rano 500 Sr Tablet 10 can be taken alongside other anti-anginal medicines such as beta-blockers or calcium channel blockers, as advised by your doctor.

What should I do if I miss a dose of Z Rano 500 Sr Tablet 10?

If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one.

Can I consume alcohol while taking Z Rano 500 Sr Tablet 10?

It's better to avoid or limit alcohol while taking Z Rano 500 Sr Tablet 10 as it can intensify certain side effects like dizziness and interfere with medicine efficacy.

Are there any dietary restrictions while taking Z Rano 500 Sr Tablet 10?

While there are no specific dietary rules, grapefruit products should be avoided as they can affect how Z Rano 500 Sr Tablet 10 is metabolised in the body.

Can anyone take Z Rano 500 Sr Tablet 10?

No, certain people, like those with severe liver impairment or known hypersensitivity to ranolazine, shouldn't take this medicine. Always consult your doctor first.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

No 183, 13thCross, Jayanagar, Mysore, Karnataka-570014

Country of origin: INDIA

References

Ranolazine. (n.d.). Medlineplus.Gov. Retrieved August 27, 2024, from https://medlineplus.gov/druginfo/meds/a606015.html
U.S. Food and Drug Administration. (2010). Ranolazine (Ranexa): Highlights of Prescribing Information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021526s012lbl.pdf
Ranolazine - StatPearls - NCBI bookshelf. (2023, May 16). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK507828/
Ranolazine. (2024, April 9). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00243

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