Wanesmo D Capsule 10

Arowana Healthcare

Strip of 10 Units

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Composition

Domperidone (30 Mg) + Esomeprazole (40 Mg)

Wanesmo D Capsule 10 is used for managing gastrointestinal disorders, including gastro-oesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. This combination belongs to the class of medications called gastrointestinal agents.

This capsule also relieves GERD symptoms such as heartburn, acid reflux, and difficulty swallowing. It assists in healing erosive oesophagitis and serves as maintenance to prevent relapse. Furthermore, it prevents nausea and vomiting, which certain medications can cause.

You're advised to take this medicine orally, exactly as your doctor directs. Before starting this medicine, inform your doctor about any existing medical conditions or ongoing medications you're on; if you observe any side effects while on this medicine, promptly report them to your doctor. It's important to continue taking the medicine for the entire duration your doctor prescribes for optimal results.

Wanesmo D Capsule 10 is used for treating the following conditions:

Manage symptoms of gastroesophageal reflux disease, such as heartburn, acid reflux and difficulty swallowing.
Healing and maintenance to prevent relapse of erosive oesophagitis.
Management and prevention of peptic ulcers.
Control of hypersecretory conditions like Zollinger-Ellison syndrome.
Prevents nausea and vomiting induced by certain medications.

Directions for Use of Wanesmo D Capsule 10

This medicine should be taken on an empty stomach, at least 1 hour before a meal or as prescribed by the doctor.
Swallow the capsule whole with a glass of water.
Avoid crushing or chewing it.
Don't stop taking this medicine without first consulting your doctor.

Wanesmo D Capsule 10 is taken orally.

Wanesmo D Capsule 10 may have the following common side effects:

Headache
Diarrhoea
Abdominal pain
Nausea
Flatulence
Constipation
Dry mouth

Managing the Side Effects:

Most side effects are temporary and generally harmless, resolved by discontinuing the use of Wanesmo D Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrohea: Try taking the Wanesmo D Capsule 10 with food to lessen the effect of diarrhoea.
Constipation: Try taking this medication at night to avoid constipation.

Wanesmo D Capsule 10 comprises two active components:

Domperidone (30 mg): This component works on dopamine receptors in your stomach and intestines. It causes an increase in motility in the upper GI tract, which prevents reflux by tightening the lower oesophagal sphincter. Additionally, it blocks a region in your brain called the chemoreceptor trigger zone to avoid feelings of nausea and vomiting.
Esomeprazole (40 mg): As a proton pump inhibitor, esomeprazole permanently blocks an enzyme system known as H+/K+ ATPase (proton pump) in cells lining your stomach. This action suppresses both basal and stimulated acid production, allowing your oesophagal and stomach lining to heal effectively.

Pregnancy

Wanesmo D Capsule 10 should be used cautiously if you are pregnant. It's recommended to consult your doctor before taking this medicine.

Breastfeeding

Discuss the potential risks and benefits with your doctor before taking this medication if you are breastfeeding or planning to breastfeed.

Alcohol

Drinking alcohol while using Wanesmo D Capsule 10 may alter its effectiveness. It's best to discuss this with your doctor.

Liver

Caution is advised while taking Wanesmo D Capsule 10 in case of mild to moderate liver impairment. This medicine is not recommended for those with severe liver diseases. Discuss your liver health status with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, caution is advised before using Wanesmo D Capsule 10. Always consult your doctor beforehand.

Using Machines & Driving

Wanesmo D Capsule 10 might cause side effects like drowsiness or dizziness, affecting your ability to operate machinery or drive. Be aware of how this medicine affects you before undertaking such tasks.

Allergy

Wanesmo D Capsule 10 is contraindicated for individuals with known hypersensitivity to domperidone, esomeprazole or any other components in the capsule.

Children

This medicine should be given cautiously to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Wanesmo D Capsule 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age as they might also have liver and kidney issues and might be on other medication.

Drug-Drug Interactions

Wanesmo D Capsule 10 interacts with the following medicines:

CYP3A4 inhibitors: Medications such as ketoconazole, itraconazole, clarithromycin, and erythromycin can interact with Wanesmo D Capsule 10, increasing the risk of QT prolongation.
pH-dependent medications: The absorption of certain medications like digoxin, ketoconazole, and iron salts may be altered when taken with Wanesmo D Capsule 10 due to its effect on stomach acid levels.
Antiplatelet medicines: Taking Wanesmo D Capsule 10 alongside medications like clopidogrel should be avoided as it may reduce the blood-thinning effect.

Drug-Food Interactions

Eating certain foods close to when you take Wanesmo D Capsule 10 could affect the medication's effectiveness.

Drug-Disease Interactions

Wanesmo D Capsule 10 interacts with the following diseases:

Liver disease: Those with moderate to severe liver impairment should be cautious when taking Wanesmo D Capsule 10 as it could exacerbate their condition.
Heart conditions: Due to the increased risks, patients with QT prolongation or cardiac arrhythmias should avoid taking the Wanesmo D Capsule 10.
Pituitary tumours: People with a prolactin-releasing pituitary tumour (prolactinoma) are advised not to take Wanesmo D Capsule 10.

Daily Dose

Take the daily recommended dose of Wanesmo D Capsule 10 as directed by your doctor. The dosage might vary according to factors such as the severity of your condition and how your body responds to this medication. Always adhere to the prescribed dosage and never increase it without your doctor's advice.

Over Dose

An accidental overdose of Wanesmo D Capsule 10 may lead to symptoms like confusion, blurred vision, and rapid heartbeat. If you experience these or any other unusual symptoms after taking more than the recommended dose, inform your doctor immediately.

Missed Dose

If you forget to take a dose of Wanesmo D Capsule 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take extra medication to make up for a missed dose without consulting your doctor.

Store Wanesmo D Capsule 10 at room temperature, ideally between 15°C and 30°C.
Protect the product from direct sunlight and moisture to maintain its efficacy.
Always keep this medicine out of reach of children.
Ensure you use the capsule before its expiry date.

To help manage your stomach conditions, avoid spicy food and citrus juices, which can aggravate acid reflux and heartburn.
Limit your intake of caffeinated beverages, as these can stimulate acid production in your stomach, potentially worsening symptoms.

Fact Box

Drug Category	Proton Pump Inhibitor, Dopamine Antagonist
Therapeutic Category	Gastrointestinal Agent
Available Dosage Types	Capsule
Habit Forming	No
Ailment	GERD, Peptic Ulcers, and Zollinger-Ellison Syndrome

What is Wanesmo D Capsule 10 used for?

Wanesmo D Capsule 10 is used to manage conditions like gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome.

How does Wanesmo D Capsule 10 work?

It contains domperidone, which enhances gut movement, and esomeprazole, which reduces stomach acid production, offering relief from various gastrointestinal disorders.

Should I take Wanesmo D Capsule 10 before or after meals?

It's best to take the medicine at least one hour before a meal. Always follow your doctor's instructions.

Can I chew or crush Wanesmo D Capsule 10?

No, you should swallow the capsule whole with water. Do not chew, crush or open it.

What are the side effects of Wanesmo D Capsule 10?

Common side effects may include headache, diarrhoea, abdominal pain, nausea and constipation. Consult your doctor if these persist or worsen.

Can I take Wanesmo D Capsule 10 while taking other medications?

Some medicines, such as ketoconazole and itraconazole, can interact with Wanesmo D Capsule 10. Always inform your doctor about all medications you are currently taking.

How should I store Wanesmo D Capsule 10?

Store it at room temperature (15°C to 30°C), away from direct sunlight and moisture. Keep out of reach of children.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Space No. 201, Krishna Plaza - ll, Sector 12, MLU, Plot No. 03, Dwarka, New Delhi, Delhi 110075

Country of origin: INDIA

References

NEXIUM (esomeprazole magnesium) for delayed-release oral suspension Initial U.S. Approval: 1989. (n.d.). Fda.Gov. Retrieved August 14, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022101s014021957s017021153s050lbl.pdf
Esomeprazole 40 mg Gastro-resistant Tablets - Patient Information Leaflet (PIL) - (emc). (n.d.). Org.uk. Retrieved September 22, 2024, from https://www.medicines.org.uk/emc/product/2326/pil
Prescribing information 1. Generic name esomeprazole (GR) & domperidone (SR) capsules. (n.d.). Bluecrosslabs.com. Retrieved September 22, 2024, from https://bluecrosslabs.com/wp-content/uploads/2024/02/S-RD%20Capsules.pdf
CDSCO. (n.d.). Gov.In. Retrieved August 14, 2024, from https://cdscoonline.gov.in/CDSCO/Drugs
Izra, D. (n.d.). For the use of a Registered Medical Practitioner or a Hospital or a Laboratory only. Torrentian.Com. Retrieved August 14, 2024, from https://www.torrentian.com/pisheet/Upload/PI_Sheet/2977.pdf

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