Vrital Am 405 Mg Tablet 10

Vrital Am 40/5 MG Tablet 10

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Composition

Amlodipine (5 Mg) + Telmisartan (80 Mg)

Vrital Am 40/5 MG Tablet 10 is primarily used to manage high blood pressure, also known as hypertension. It is a combination medicine that belongs to the class of antihypertensives, which work to reduce the pressure in your blood vessels.

This medicine offers comprehensive control over blood pressure compared to using just one of its components. Its dual action makes it effective at maintaining a healthier blood pressure level, regardless of age, gender, weight, or Body Mass Index (BMI).

Before you start taking this medicine, it's important to consult your doctor and inform them about any ongoing medications or pre-existing conditions you have. If you notice any side effects while on this medicine, make sure to notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Vrital Am 40/5 MG Tablet 10 is used for the following conditions:

Managing high blood pressure, also known as hypertension.
Keeping chronic stable angina under control. This is a type of chest pain that occurs when your heart doesn't get enough blood.
Managing vasospastic angina, which happens when the arteries supplying your heart become narrow or blocked.
Controlling coronary artery disease, a condition where plaque builds up inside the coronary arteries, which supply oxygen-rich blood to your heart muscle.

Directions for Use of Vrital Am 40/5 MG Tablet 10

The whole tablet is taken orally with a glass of water.
Make sure not to crush or chew the tablet.
It's crucial not to take more than the dose recommended by your doctor.

Vrital Am 40/5 MG Tablet 10 is taken orally.

Side Effects of Vrital Am 40/5 MG Tablet 10

Vrital Am 40/5 MG Tablet 10 may have the following common side effects:

Headache
Dizziness
Nausea
Back pain
Fatigue
Peripheral oedema: This is swelling in your limbs caused by a buildup of fluid.
Flushing: You may experience a sudden reddening of your skin.
Palpitations: These are feelings of having a rapid, fluttering, or pounding heart.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Vrital Am 40/5 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Vrital Am 40/5 MG Tablet 10 with food to reduce this effect.
Fatigue: If you feel tired after taking this medicine, consider taking it at bedtime.

Vrital Am 40/5 MG Tablet 10 consists of two active ingredients that work together in your body:

Amlodipine (5 mg): This ingredient is a calcium channel blocker. It functions by inhibiting the movement of calcium ions into the smooth muscle cells lining your blood vessels and heart. This action results in relaxation and widening of your blood vessels (vasodilation), reducing the resistance against which your heart needs to pump blood and lowering your blood pressure.
Telmisartan (80 mg): This component is an angiotensin II receptor antagonist. It specifically binds to a receptor subtype called AT1 in your body. By blocking the effect of angiotensin II – a substance that constricts your blood vessels and releases a hormone called aldosterone – telmisartan promotes relaxation and widening of your blood vessels (vasodilation) and reduces aldosterone-induced water retention. These actions collectively lower your blood pressure.

Pregnancy

If you are pregnant, exercise caution while using Vrital Am 40/5 MG Tablet 10. Telmisartan in the formulation is not recommended, especially during the 2nd and 3rd trimesters due to potential harm to the foetus. Always consult your doctor before starting this medicine if you're pregnant or planning to conceive.

Breastfeeding

The use of Vrital Am 40/5 MG Tablet 10 while breastfeeding is not recommended. It's crucial to discuss this with your doctor to understand the potential risks and benefits.

Alcohol

While taking Vrital Am 40/5 MG Tablet 10, it is advisable to limit your alcohol intake as it may increase the risk of dizziness and further lower your blood pressure.

Liver

For those with mild to moderate liver impairment, caution is advised when taking Vrital Am 40/5 MG Tablet 10. This medicine should not be used if you have severe liver problems or biliary obstructive disorders. Discuss your liver health with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, it's essential to consult your doctor before taking Vrital Am 40/5 MG Tablet 10. Regular monitoring of serum electrolytes and creatinine levels is advised.

Using Machines & Driving

This medicine might cause dizziness or tiredness. If you experience these effects, avoid driving or operating heavy machinery until you feel well again.

Allergy

Vrital Am 40/5 MG Tablet 10 should not be taken if you have known hypersensitivity to amlodipine, telmisartan, or any other components in the formulation.

Children

Vrital Am 40/5 MG Tablet 10 is not recommended for use in children under 18 years of age.

Older Patients

Elderly patients should take Vrital Am 40/5 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised especially for patients above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Vrital Am 40/5 MG Tablet 10

Drug-Drug Interactions

Vrital Am 40/5 MG Tablet 10 interacts with the following medicines:

Potassium-Sparing Diuretics: Taking Vrital Am 40/5 MG Tablet 10 alongside medicines such as amiloride and spironolactone can increase the risk of high potassium levels in your blood (hyperkalaemia).
Non-Steroidal Anti-inflammatory Drugs (NSAIDs): When used with Vrital Am 40/5 MG Tablet 10, NSAIDs like ibuprofen and naproxen can reduce the blood pressure-lowering effects of the tablet and increase the risk of kidney problems.
Statins: The blood levels of simvastatin, a cholesterol-lowering medication, may be increased when taken with Vrital Am 40/5 MG Tablet 10.
Heart Medications: Telmisartan in Vrital Am 40/5 MG Tablet 10 may increase the levels of digoxin, a heart medication, in your blood.

Drug-Food Interactions

There is no evidence of Vrital Am 40/5 MG Tablet 10 interacting with foods.

Drug-Disease Interactions

Vrital Am 40/5 MG Tablet 10 interacts with the following diseases:

Liver Disease: People with liver disease should exercise caution while taking this medication as it can affect how the medicine works.
Diabetes: This medicine can affect sugar control in diabetic patients.
Heart Conditions: Patients with severe congestive heart failure or other heart conditions such as aortic or mitral valve stenosis should use this medicine cautiously.

Daily Dose

The daily dose of Vrital Am 40/5 MG Tablet 10 should be as prescribed by your doctor. This could vary based on factors such as how severe your condition is and how you respond to the medicine. For the most effective results, it's crucial to stick to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

Applying more Vrital Am 40/5 MG Tablet 10 than prescribed can lead to common side effects like headache, dizziness, and nausea. If these symptoms persist or worsen, it's best to inform your doctor.

Missed Dose

If you forget to take a dose of Vrital Am 40/5 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule.

Store Vrital Am 40/5 MG Tablet 10 at room temperature, ideally below 30°C.
Keep the tablets in a tightly closed container to protect from light and moisture.
Ensure children cannot access the medication.
Always check the expiry date before use.

Maintain a low-salt diet as high sodium levels can increase blood pressure, worsening hypertension.
Regular physical activity like walking or cycling can help lower blood pressure; aim for 30 minutes of moderate activity in a week.

Fact Box

Drug Category	Calcium Channel Blocker, Angiotensin II Receptor Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Chronic Stable Angina

What is Vrital Am 40/5 MG Tablet 10 used for?

This tablet is generally used to manage high blood pressure, offering more comprehensive control than amlodipine or telmisartan alone.

How does Vrital Am 40/5 MG Tablet 10 work?

This tablet contains amlodipine and telmisartan, which work together to relax blood vessels, reduce resistance, and lower blood pressure.

How should I take Vrital Am 40/5 MG Tablet 10?

Take this tablet orally with water, at the same time every day. It can be taken with or without food, but do not crush or split it. Follow your doctor's instructions.

What if I miss a dose of Vrital Am 40/5 MG Tablet 10?

If you miss a dose, take it as soon as you remember. But if it's near the time for your next dose, skip the missed one and continue your usual schedule.

Are there any side effects of Vrital Am 40/5 MG Tablet 10?

Common side effects include headache, dizziness, fatigue, nausea and back pain. If any side effects bother you or persist, consult your doctor immediately.

Can I take Vrital Am 40/5 MG Tablet 10 while pregnant?

No, it should not be administered during pregnancy due to potential risks to the fetus. Always consult your doctor before taking any medication during pregnancy.

Can I take other medicines while on Vrital Am 40/5 MG Tablet 10?

Most medicines are safe to take with this one, but always inform your doctor about all medicines you're currently taking to check for potential interactions.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

336, Industrial Area, Phase-II, Panchkula 134109

Country of origin: INDIA

References

National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 2162, Amlodipine. Retrieved June 28, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Amlodipine.
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 65999, Telmisartan. Retrieved June 28, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Telmisartan.
Josefsson, M., Zackrisson, A., & Ahlner, J. (1996). Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers. European Journal of Clinical Pharmacology, 51(2), 189-193. https://doi.org/10.1007/s002280050183
Amlodipine: Uses, Interactions, Mechanism of Action | DrugBank Online https://go.drugbank.com/drugs/DB00381
Sharpe M, Jarvis B, Goa KL: Telmisartan: a review of its use in hypertension. Drugs. 2001;61(10):1501-29.https://go.drugbank.com/articles/A1489

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