Valentas 50 Mg Tablet 10

Valentas 50 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹273.9~~

₹224.6

₹27.39/Units

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Composition

Sacubitril (24 Mg) + Valsartan (26 Mg)

Valentas 50 Tablet is a combination medication used to treat chronic heart failure. It helps reduce the risk of hospitalization and death by improving the heart's pumping ability, alleviating symptoms like shortness of breath, fatigue, and swelling in the ankles and feet.

This tablet works by relaxing and widening blood vessels, making it easier for the heart to pump blood throughout the body. For optimal results, it should be used alongside lifestyle changes, including a healthy diet, regular exercise, and stress management.

This medicine should be taken orally, as instructed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or current medications before you start taking this medicine. If you experience any side effects while on this medication, notify your doctor promptly.

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Valentas 50 Tablet is used for managing chronic heart failure, improving heart function, reducing symptoms like breathlessness and swelling, and enhancing energy levels and quality of life.

Directions for Use of Valentas 50 Tablet 10

Follow these instructions while taking Valentas 50 Tablet:

Swallow the tablet whole with a sufficient amount of water.
Do not crush or chew the tablet.
Take this medicine at the same time each day to ensure optimal results.
Continue taking this medicine regularly, even if you start feeling better; stopping abruptly may worsen your condition.
Consult your doctor for precise instructions on how to use this medicine.

Valentas 50 Tablet is taken orally.

While taking Valentas 50 Tablet, you might experience some of the following common side effects:

Low blood pressure (hypotension)
High potassium levels (hyperkalemia)
Angioedema

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Valentas 50 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some simple ways you can manage certain side effects:

Low blood pressure (hypotension): Try to stand up slowly from a sitting or lying position to minimise dizziness.
High potassium levels (hyperkalemia): Limit your intake of potassium-rich foods such as bananas and leafy greens.

Valentas 50 Tablet consists of two active ingredients:

Sacubitril (24 mg): This component actively reduces the activity of neprilysin, an enzyme that usually breaks down natriuretic peptides. By preventing these peptides from degrading, sacubitril increases their levels in the body. These peptides are beneficial for the heart and blood vessels as they promote sodium excretion, decrease blood volume, and cause vasodilation.
Valsartan (26 mg): Valsartan falls under the category of angiotensin receptor blockers (ARB). It works by blocking the action of angiotensin II, a hormone that tightens blood vessels and increases blood pressure. By stopping angiotensin II from binding to its receptors, valsartan helps relax blood vessels, reduce blood pressure, and lessen the strain on the heart.
These combined effects of sacubitril and valsartan lead to better heart function, alleviation of heart failure symptoms, and overall improved cardiovascular health.

Pregnancy

Valentas 50 Tablet should be discontinued as soon as pregnancy is suspected. Consult your doctor immediately if you are pregnant or planning to conceive.

Breastfeeding

Valentas 50 Tablet is not recommended for breastfeeding women. Before using this medicine while nursing, it's best to consult your doctor.

Alcohol

It's wise to discuss your alcohol intake with your doctor when taking this medication.

Liver

Caution is advised while taking Valentas 50 Tablet if you have mild to moderate liver problems. In cases of severe liver diseases, this medicine should be used cautiously. Consult your doctor about any liver-related concerns before starting this medication.

Kidney

Caution is advisable for patients with a history of kidney issues who are considering using Valentas 50 Tablet. Regular kidney function tests are necessary during treatment. Consult your doctor for more information.

Using Machines & Driving

Valentas 50 Tablet may cause dizziness or lightheadedness in some patients, which could affect the ability to drive or operate machinery. If you experience these side effects, avoid such activities until you feel well enough.

Allergy

If you have ever experienced allergic reactions to sacubitril, valsartan, or any other component of Valentas 50 Tablet, it's important to inform your doctor before starting this medicine.

Children

Valentas 50 Tablet is meant for adult use. It should not be given to children under 18 years of age without medical supervision.

Older Patients

Older patients can use Valentas 50 Tablet under medical supervision since they may be more susceptible to its side effects. If you're above 70 years old, discuss with your doctor about your health status before using this medicine.

Drug-Drug Interactions

Blood Pressure-Lowering Medicines: If you're taking medicines like losartan or amlodipine, the blood pressure-lowering effects of Valentas 50 Tablet may amplify, potentially leading to excessively low blood pressure.
Potassium Supplements or Potassium-Sparing Diuretics: Medicines like spironolactone can increase the risk of high potassium levels in the blood when used alongside Valentas 50 Tablet.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs like ibuprofen may reduce the blood pressure-lowering effect of Valentas 50 Tablet and potentially worsen kidney function.

Drug-Food Interactions

Valentas 50 Tablet doesn't have known specific interactions with any food products. However, it's always advisable to take it as directed by your doctor.

Drug-Disease Interactions

Kidney Disease: Patients with severe kidney impairment may need dosage adjustment. Regular kidney function tests are essential during treatment with Valentas 50 Tablet.
Liver Disease: For patients with severe liver impairment, this medicine should be used cautiously.
Angioedema: Patients who have experienced swelling of the face, lips, tongue or throat in the past should be closely monitored while taking Valentas 50 Tablet.

Daily Dose

The daily dose of Valentas 50 Tablet should be as directed by your doctor. The dosage may vary based on individual response and condition severity. Always adhere to the prescribed dosage.

Over Dose

An overdose of Valentas 50 Tablet may lead to symptoms such as light-headedness or dizziness due to excessively lowered blood pressure. If you suspect an overdose, consult your doctor.

Missed Dose

If you forget to take your Valentas 50 Tablet, take it as soon as you remember. If it's near your next dose time, skip the missed dose and resume your schedule.

Store Valentas 50 Tablet at room temperature, ideally not exceeding 30°C.
Keep it in its original packaging to safeguard it from moisture.
Avoid exposure to direct sunlight.
Always keep the medicine out of sight and reach of children.
Ensure the medication is used prior to the expiry date indicated on the package.

As Valentas 50 Tablet is aimed at managing chronic heart failure, a low-sodium diet can be beneficial. High sodium intake may lead to fluid retention, putting additional stress on your heart.
Regular light exercise, such as walking or gardening, can help keep your cardiovascular system healthy. However, always consult your doctor before starting any new fitness regime.

Fact Box

Drug Category	Neprilysin Inhibitor, Angiotensin Receptor Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Heart Failure

What is Valentas 50 Tablet used for?

Valentas 50 Tablet is used to manage chronic heart failure in adults, helping to reduce symptoms like breathlessness, fatigue, and swelling.

How does Valentas 50 Tablet work?

The medicine combines sacubitril and valsartan. Sacubitril increases beneficial heart peptides, while valsartan blocks a hormone that raises blood pressure.

How should I take Valentas 50 Tablet?

You should take Valentas 50 Tablet orally, as directed by your doctor. It's important to take it at the same time daily for optimal results.

Can I stop taking Valentas 50 Tablet if I feel better?

No, you should continue taking the medicine even if you feel better. Stopping abruptly may worsen heart failure symptoms.

What are some common side effects of Valentas 50 Tablet?

Some common side effects include low blood pressure, increased potassium levels in the blood, and kidney impairment. Consult your doctor if these persist.

Are there any precautions I should take while using Valentas 50 Tablet?

Patients with a history of angioedema or kidney disease should use Valentas 50 Tablet cautiously. Pregnant and breastfeeding women should not use this medicine.

Can Valentas 50 Tablet interact with other medicines?

Yes, it can interact with blood pressure-lowering medications, potassium supplements or diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Inform your doctor about all medications you're taking.

Last Updated On 23 Nov. 2024 | 8:50AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

Sacubitril: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09292
Valsartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00177
Novartis Pharmaceuticals Corporation. (2021). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/207620s018lbl.pdf
DailyMed - ENTRESTO- sacubitril and valsartan tablet, film coated ENTRESTO- sacubitril and valsartan pellet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=000dc81d-ab91-450c-8eae-8eb74e72296f

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