Uthyrox 75 Mcg Tablet 100

Uthyrox 75 MCG Tablet 100

Merck Ltd

Pack of 100 Units

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MRP ~~₹136.64~~

₹112.04

₹1.37/Units

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Prescription required for this medicine

Store Below 30^o C

Composition

Thyroxine (75 Mcg)

Strength:

25 MCG 75 MCG 50 MCG 100 MCG

Uthyrox 75 MCG Tablet 100 is primarily utilised to manage hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. This medicine is part of a group known as thyroid hormones.

Beyond its main use, this medicine is also used to manage secondary hypothyroidism due to pituitary or hypothalamic disorders and tertiary hypothyroidism from disorders of the hypothalamus-pituitary-thyroid axis. Supplementing deficient thyroxine levels helps normalise metabolism and alleviate symptoms associated with these conditions.

It's also important to inform your doctor about ongoing medications or pre-existing diseases. If you notice any side effects while taking this medicine, let your doctor know immediately. Remember, for best results, you should continue taking the medicine for the duration prescribed by your doctor.

Uthyrox 75 MCG Tablet 100 is used for the following:

Managing primary hypothyroidism, a condition that arises when your thyroid gland doesn't produce enough thyroxine
Handling secondary hypothyroidism, which includes pituitary or hypothalamic disorders causing insufficient thyroxine production
Addressing tertiary hypothyroidism, a condition resulting from disorders of the hypothalamus-pituitary-thyroid axis

Directions for Use of Uthyrox 75 MCG Tablet 100

Here's how to take Uthyrox 75 MCG Tablet 100:

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Uthyrox 75 MCG Tablet 100 is taken orally.

Side Effects of Uthyrox 75 MCG Tablet 100

Uthyrox 75 MCG Tablet 100 may have the following common side effects:

Irregular heartbeat
Chest pain or tightness
Shortness of breath
Headache
Nervousness or irritability
Trouble sleeping
Tremors
Muscle weakness
Change in appetite or weight
Diarrhoea or vomiting
Skin rash or itching

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing Uthyrox 75 MCG Tablet 100. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Drink plenty of healthy fluids to stay hydrated and follow the diet recommended by your doctor.
Nervousness or irritability: If these conditions occur after taking this medicine, consider taking it at bedtime after asking your doctor.

Uthyrox 75 MCG Tablet 100 contains synthetic Thyroxine (75 Mcg) as its active ingredient. Here's how it works:

Absorption and Binding: After you take the tablet, the thyroxine gets absorbed into your bloodstream through your gut. It then enters cells throughout your body and binds to specific receptors in the nucleus.
Activation of Genes: Once bound to the receptors, thyroxine activates genes that produce proteins that regulate various bodily functions.
Stimulation of Metabolism: Thyroxine increases cellular metabolism, stimulates the synthesis of RNA and proteins, and boosts the metabolic rate.
Regulation of Growth and Development: Thyroxine plays a pivotal role in tissue growth and differentiation and the development of the skeletal and nervous systems.

Pregnancy

If you are pregnant, your requirement for thyroxine may increase. It is recommended to consult your doctor and have your TSH levels monitored every 4 weeks during pregnancy to make appropriate dosage adjustments.

Breastfeeding

Uthyrox 75 MCG Tablet 100 can be taken while breastfeeding as thyroxine is naturally present in breast milk. However, consult your doctor for advice based on your specific circumstances.

Alcohol

It's wise to discuss this with your doctor before consuming alcohol while on this medication.

Liver

There are no specific precautions required for liver health when taking Uthyrox 75 MCG Tablet 100. However, if you have any liver-related issues, it would be prudent to discuss them with your doctor before starting this medicine.

Kidney

Caution is advised while taking Uthyrox 75 MCG Tablet 100 if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

Uthyrox 75 MCG Tablet 100 does not generally interfere with the ability to drive or use machines. But if you experience side effects like dizziness or impaired vision, it is best to avoid driving or operating machinery until these subside.

Allergy

You should avoid taking Uthyrox 75 MCG Tablet 100 if you have a known hypersensitivity or allergy to any formulation component. Discuss any known allergies with your doctor before starting this medication.

Children

Caution is advised while giving Uthyrox 75 MCG Tablet 100 to children under 18. Always consult your doctor before giving this medicine to a child.

Older Patients

Elderly patients should take Uthyrox 75 MCG Tablet 100 under medical supervision as they may be more sensitive to thyroid hormones. Caution is advised, especially for patients above 70, as they might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.

Interactions of Uthyrox 75 MCG Tablet 100

Drug-Drug Interactions

Uthyrox 75 MCG Tablet 100 interacts with the following medicines:

Antacids: Medications like aluminium hydroxide and calcium carbonate can reduce the absorption of thyroxine, potentially decreasing its effectiveness in managing hypothyroidism.
Antidepressants: Tricyclic antidepressants such as amitriptyline can increase the effects of thyroxine, possibly leading to an enhanced risk of side effects such as increased heart rate and anxiety.
Diabetes Medications: Medicines like metformin may alter the glucose levels in the body, necessitating adjustments in thyroxine dosage to maintain optimal thyroid function.
Anticoagulants: Warfarin, an anticoagulant, can have increased effects when taken with thyroxine, raising the risk of bleeding and requiring close monitoring of blood coagulation parameters.

Drug-Food Interactions

Soybean flour, cotton seed meal, and walnuts may decrease the absorption of Uthyrox 75 MCG Tablet 100.

Drug-Disease Interactions

Uthyrox 75 MCG Tablet 100 interacts with the following diseases:

Cardiovascular Disorders like Hypertension or Arrhythmias: Patients with these conditions should use Uthyrox 75 MCG Tablet 100 cautiously, as it could potentially exacerbate heart-related symptoms.
Diabetes Mellitus: This medicine can alter insulin or antidiabetic medicine requirements, necessitating close glucose level monitoring.
Long-standing Hypothyroidism: These patients need to have their dosage slowly incremented due to their sensitivity to thyroid hormones.
Concomitant Adrenal Insufficiency: Patients with this condition may require higher doses of Uthyrox 75 MCG Tablet 100.

Daily Dose

Your doctor will prescribe the daily dose of Uthyrox 75 MCG Tablet 100 based on your individual condition and response to treatment. Always follow their instructions and don’t exceed the prescribed dosage.

Over Dose

Overdosing on Uthyrox 75 MCG Tablet 100 might cause symptoms like restlessness, rapid heartbeat, or excessive sweating. If you experience these symptoms, contact your doctor right away.

Missed Dose

If you miss a dose of Uthyrox 75 MCG Tablet 100, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one.

Store Uthyrox 75 MCG Tablet 100 at room temperature below 30°C.
Keep it away from excessive heat, light, and moisture.
Make sure it's kept out of the reach and sight of children.
Remember to use the medicine before its expiry date.

Maintain a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support overall health and metabolism, essential for managing hypothyroidism.
Regular physical activity, such as walking or yoga, can also help manage weight gain and fatigue associated with hypothyroidism. Always consult with your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Thyroid Hormone
Therapeutic Category	Thyroid Therapy
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Primary Hypothyroidism, Secondary Hypothyroidism, Tertiary Hypothyroidism

What Is Uthyrox 75 MCG Tablet 100 Used For?

Uthyrox 75 MCG Tablet 100 is used to manage conditions such as primary, secondary, and tertiary hypothyroidism, where the body doesn't produce enough thyroid hormones.

How Does Uthyrox 75 MCG Tablet 100 Work?

The active ingredient, thyroxine, in Uthyrox 75 MCG Tablet 100 supplements the body's deficient thyroid hormone levels, helping restore normal metabolic functions.

When Should You Take Uthyrox 75 MCG Tablet 100?

Uthyrox 75 MCG Tablet 100 should be taken orally, preferably on an empty stomach, as your doctor advises.

What Are Some Common Side Effects of Uthyrox 75 MCG Tablet 100?

Common side effects may include irregular heartbeat, headache, nervousness, muscle weakness, change in appetite or weight, diarrhoea and skin rash. Consult your doctor if these persist.

Can Pregnant Women Take Uthyrox 75 MCG Tablet 100?

Yes. However, thyroxine requirements may change during pregnancy. Regular monitoring every four weeks is advised to make appropriate dose adjustments.

Are There Any Specific Precautions While Using Uthyrox 75 MCG Tablet 100?

Caution is advised for elderly patients, patients with cardiovascular disorders, and patients with diabetes mellitus. It's also crucial to avoid certain foods that can impair absorption.

How Should I Store My Uthyrox 75 MCG Tablet 100?

Keep your Uthyrox 75 MCG Tablet 100 at room temperature, away from light and moisture, and out of children's reach.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Godrej One, 8th floor, Pirojsha Nagar,, Eastern Express Highway,, Vikroli East, Mumbai, Maharashtra 400079

Country of origin: INDIA

References

Highlights of prescribing information. (2002). [Press-release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021342s023lbl.pdf
Highlights of prescribing information. (2002). [Press-release]. SYNTHROID. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021402s036lbl.pdf
Pfizer, Inc. (2001). LEVOXYL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021301s038lbl.pdf
Eghtedari, B., & Correa, R. (2023, August 28). Levothyroxine. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK539808/
Levothyroxine: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00451

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