Udca 300 Mg Tablet 10

Udca 300 MG Tablet 10

Abbott India Ltd.

Pack of 10 Units

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MRP ~~₹149~~

₹122.18

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Composition

Ursodeoxycholic Acid (300 Mg)

UDCA-300 Tablet is primarily used to dissolve gallstones in people who have a functioning gallbladder but cannot undergo surgery. This medicine is part of a group known as bile acids.

This tablet also plays a crucial role in managing primary biliary cholangitis, an autoimmune liver disease that damages the bile ducts. Additionally, it's used to manage bile acid synthesis disorders and liver dysfunction in children who are 6 years and older with cystic fibrosis.

Before you start taking this medicine, consult your doctor about the dose and frequency. It's important to inform your doctor about any pre-existing conditions or ongoing medications you may have. If you experience any side effects while on this medicine, notify your doctor immediately. Make sure you continue taking the medicine for the duration prescribed by your doctor for the best results.

UDCA-300 Tablet is used for the following:

Dissolving cholesterol gallstones in individuals who have a functioning gallbladder and can't have surgery
Managing primary biliary cholangitis, an autoimmune disease that damages the bile ducts in your liver
Helping with bile acid synthesis disorders and liver failure in children aged 6 and above who have cystic fibrosis

Directions for Use of Udca 300 MG Tablet 10

Here's how you should take UDCA-300 Tablet:

Take the tablet with food.
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Stick to a regular dosing schedule to get the best results.
It's crucial not to stop taking this medicine without first consulting your doctor.

UDCA-300 Tablet is taken orally.

Taking UDCA-300 Tablet may lead to some common side effects such as:

Diarrhoea
Nausea
Abdominal discomfort
Headache
Alopecia: This is a condition where hair thinning or hair loss occurs.
Skin rash or itching

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of UDCA-300 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking UDCA-300 Tablet with food as it can help reduce this effect.
Abdominal discomfort: If you feel discomfort in your abdomen after taking this medication, you might find it helpful to take the tablet after meals.

UDCA-300 Tablet consists of a single active ingredient: Ursodeoxycholic Acid (300mg). Here's how it works:

Reducing Cholesterol Secretion: Ursodeoxycholic acid decreases the secretion of cholesterol into your bile by inhibiting cholesterol synthesis and absorption.
Dissolving Gallstones: By increasing the solubility of cholesterol in bile, it helps in dissolving gallstones.
Protecting Liver Cells: It replaces or displaces toxic concentrations of other bile acids that can damage liver cells.
Stimulating Bile Flow: This medicine stimulates bile flow and bicarbonate-rich ductular secretion, protecting against bile acid toxicity.
Slowing Disease Progression: Ursodeoxycholic acid can exert immunomodulatory and anti-inflammatory effects that may slow liver disease progression.

Pregnancy

Caution is advised while taking UDCA-300 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

UDCA-300 Tablet may be used during breastfeeding as minimal amounts are excreted in breast milk. However, it's wise to consult your doctor before using this medication.

Alcohol

There is no known interaction between UDCA-300 Tablet and alcohol. But, as with any medicine, it's always a good idea to speak to your doctor first.

Liver

Patients with variceal bleeding, ascites or hepatic encephalopathy should be closely monitored when taking UDCA-300 Tablet. Regular liver function tests should be conducted every 1-3 months, especially when starting therapy.

Kidney

There aren't any specific concerns related to kidney health with UDCA-300 Tablet. However, caution is advised if you have any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There are no known effects of UDCA-300 Tablet on the ability to drive or operate machinery.

Allergy

UDCA-300 Tablet is contraindicated in patients with known hypersensitivity to bile acids including UDCA. If you've had allergic reactions to medications in the past, it would be prudent to discuss this with your doctor.

Children

UDCA-300 Tablet can be used in children aged 6 years and above for managing bile acid synthesis disorders and liver dysfunction associated with cystic fibrosis. Always consult your doctor before starting this medication.

Older Patients

Older patients should take UDCA-300 Tablet under medical supervision as they may be more sensitive to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

UDCA-300 Tablet interacts with the following medicines:

Antacids containing aluminium or smectite: These medicines may decrease the absorption of UDCA-300 Tablet, reducing its efficacy.
Bile Acid Sequestrants like cholestyramine and colestipol: These agents can bind to UDCA-300 Tablet in your digestive tract, inhibiting its absorption and action.
Medicines metabolised by CYP3A4 enzymes like oral contraceptives and cyclosporine: The interaction may alter the metabolism of these drugs, affecting their levels in your body.
Lipid-lowering agents like clofibrate: These medicines can increase the elimination of UDCA-300 Tablet, potentially reducing its effectiveness.

Drug-Food Interactions

There are no specific known food interactions with UDCA-300 Tablet. However, as a general guideline, it's always best to consume the medication as advised by your doctor.

Drug-Disease Interactions

UDCA-300 Tablet interacts with the following diseases:

Complete Biliary Obstruction: In patients where bile cannot enter the intestine, this medicine should not be used due to potentially worsened obstruction.
Frequent episodes of biliary colic: Patients suffering from frequent episodes of biliary colic should use this medicine with caution as it might provoke more attacks.

Daily Dose

Your doctor will determine the appropriate daily dose of UDCA-300 Tablet for you. This decision will be based on various factors including your overall health condition and how your body responds to the medication. For a more detailed understanding of the dosage, please refer to the package insert.

Over Dose

Overdosing on UDCA-300 Tablet might lead to discomforting side effects like diarrhoea, nausea and abdominal discomfort. In such cases, it's wise to inform your doctor about the situation.

Missed Dose

If you miss a dose of UDCA-300 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, then skip the missed one and continue with your regular schedule. Remember not to increase your dosage without consulting your doctor.

Store the UDCA-300 Tablet at room temperature, ideally between 20°C and 25°C.
Protect the medicine from light and moisture by keeping the container tightly sealed.
Keep the medicine out of sight and reach of children to avoid accidental ingestion.
Remember to discard any unused medication after its expiry date.

Ensure low cholesterol intake: Since this medicine is primarily used to dissolve cholesterol gallstones, a diet low in cholesterol can be beneficial. Opt for lean meats, fish, fruits, vegetables, and whole grains.
Stay hydrated: Increasing your water intake can help manage potential side effects like diarrhoea and help maintain a healthy digestive system.

Fact Box

Drug Category	Bile Acid
Therapeutic Category	Gallstone Dissolving Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gallstones, Primary Biliary Cholangitis

What is the primary use of UDCA-300 Tablet?

UDCA-300 Tablet is primarily used to dissolve cholesterol gallstones and manage certain liver disorders such as primary biliary cholangitis.

How does UDCA-300 Tablet work?

UDCA-300 Tablet reduces cholesterol levels in bile and protects liver cells from toxic effects of excess bile acids, helping to manage liver disorders.

Can I take UDCA-300 Tablet during pregnancy?

UDCA-300 Tablet should be used with caution during pregnancy. It's important to discuss this with your doctor if you are pregnant or planning pregnancy.

What should I do if I miss a dose of UDCA-300 Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for the next dose, skip the missed dose and continue your regular schedule.

Can I stop taking UDCA-300 Tablet on my own?

No, you should never stop taking UDCA-300 Tablet without consulting your doctor, even if your symptoms improve.

Are there any side effects of taking UDCA-300 Tablet?

Common side effects include diarrhoea, nausea, abdominal discomfort, headache and skin rash. If these persist or worsen, consult your doctor immediately.

Can I take other medicines while using UDCA-300 Tablet?

Certain medicines can interfere with the absorption of UDCA-300 Tablet. Always consult your doctor before starting any new medication while using UDCA-300 Tablet.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

3, Corporate Park, Sion Trombay Road, Mumbai - 400 071, India

Country of origin: INDIA

References

Banales, J. M., Huebert, R. C., Karlsen, T., Strazzabosco, M., LaRusso, N. F., & Gores, G. J. (2021). Cholangiocyte pathobiology. Nature Reviews Gastroenterology & Hepatology, 18, 224–241. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578816/. Accessed on 1 April 2024.
U.S. Food and Drug Administration. (2013). Ursodiol (Ursodeoxycholic Acid) Capsules, USP 300 mg. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020675s022lbl.pdf. Accessed on 1 April 2024.
Ursodeoxycholic acid - StatPearls - NCBI bookshelf. (2023, February 12). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK545303/

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