Tilstigmin 15 Mg Tablet 10

Tilstigmin Tablet 10

Tablets India Ltd

Strip of 10 Units

Read Info

MRP ~~₹51.29~~

₹43.91

₹5.13/Units

14.38% off

*MRP inclusive of all taxes

Get it By

Change

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30^o C

Composition

Neostigmine (15 Mg)

Tilstigmin Tablet is primarily utilised to manage myasthenia gravis, a condition that causes muscle weakness and fatigue. This medication belongs to a class of medicines known as cholinesterase inhibitors.

In addition to managing myasthenia gravis, this tablet is also used for managing paralytic ileus, a condition where intestinal movements are impaired. It's also used for managing postoperative urinary retention, reversing the effects of non-depolarising skeletal muscle relaxants used during surgery and normalising intestinal movements.

You should take this medicine as directed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while on this medicine, notify your doctor without delay. Make sure you continue taking the medicine for the duration prescribed by your doctor for optimal results.

Tilstigmin Tablet is used for the following:

Managing myasthenia gravis, an autoimmune disorder causing muscle fatigue
Assisting in the management of paralytic ileus or intestinal paralysis
Helping to manage postoperative urinary retention issues
Reversing the effects of non-depolarizing skeletal muscle relaxants after surgery
Aiding in normalising intestinal movements

Directions for Use of Tilstigmin Tablet 10

Here are the instructions for taking Tilstigmin Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Always take this medicine exactly as directed by your doctor.
Remember, it's important not to stop taking this medicine without consulting your doctor first.

Tilstigmin Tablet is taken orally.

Tilstigmin Tablet may have the following common side effects:

Nausea and vomiting
Diarrhoea and abdominal cramps
Increased salivation and sweating
Miosis: This refers to the constriction of the pupils of your eyes.
Increased bronchial secretions: This means you may observe an increase in mucus production in your bronchial tubes, which can lead to a cough or congestion.
Slow heartbeat and low blood pressure
Muscle twitching

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Tilstigmin Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and vomiting: These issues may be reduced if you take Tilstigmin Tablet with food or milk.
Diarrhoea: To manage this, consider taking Tilstigmin Tablet with meals.

Tilstigmin Tablet contains neostigmine (15 mg) and works on the body as follows:

Cholinesterase Inhibition: Neostigmine works by preventing the breakdown of a neurotransmitter called acetylcholine by an enzyme known as acetylcholinesterase. With more acetylcholine available in the neuromuscular junction, the communication between nerves and muscles is enhanced, improving muscle strength and contraction in conditions like myasthenia gravis.
Muscarinic Receptor Stimulation: Neostigmine also stimulates certain receptors called muscarinic receptors, leading to an increase in smooth muscle contractions in the gastrointestinal and urinary tracts. This action aids in relieving conditions like paralytic ileus and urinary retention.

Pregnancy

Caution is advised when taking Tilstigmin Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Tilstigmin Tablet should be used with caution while breastfeeding as it is known to be excreted in breast milk. Always consult your doctor before using this medicine.

Alcohol

No specific precautions are listed, but it's a good idea to ask your doctor about consuming alcohol while taking Tilstigmin Tablet.

Liver

If you have any liver issues, it's wise to consult your doctor before starting Tilstigmin Tablet. This medicine could potentially affect liver function.

Kidney

Caution is recommended if you have a history of kidney problems. Before starting on Tilstigmin Tablet, have a chat with your doctor.

Using Machines & Driving

Tilstigmin Tablet may affect some people's ability to drive or operate machinery due to potential side effects like dizziness or vision problems. It's advisable to avoid such activities until you know how the medicine affects you.

Allergy

If you have any known allergy to neostigmine or any other ingredients in Tilstigmin Tablet, do not take this medicine. Inform your doctor about any adverse reactions in the past.

Children

The safety and efficacy of Tilstigmin Tablet in children below 18 years haven't been established yet. Therefore, caution is advised when giving this medicine to children. Always consult your doctor first.

Older Patients

Older patients should use Tilstigmin Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised especially for patients above 70 years of age who might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tilstigmin Tablet interacts with the following medicines:

Muscle Relaxants such as atracurium, pancuronium, and tubocurarine: Tilstigmin Tablet may prolong their effects, causing extended muscle relaxation.
Anticholinergic Medicines like atropine and glycopyrrolate: These medicines could reduce the effectiveness of Tilstigmin Tablet.
Anaesthetic Agent like succinylcholine: If taken after Tilstigmin Tablet, it may cause prolonged paralysis.

Drug-Food Interactions

There are no specific food items that have been reported to interact with Tilstigmin Tablet.

Drug-Disease Interactions

Tilstigmin Tablet interacts with the following diseases:

Asthma: Tilstigmin Tablet use may need to be adjusted in patients with asthma due to its potential to increase bronchial secretions.
Seizures: The medicine should be used carefully in patients with a history of seizures.
Hyperthyroidism: Patients with hyperthyroidism should be cautious when using Tilstigmin Tablet as it may exacerbate symptoms.
Bradycardia (Slow Heartbeat): This medicine may further slow down the heart rate in patients already having bradycardia.
Parkinson's Disease: It's important to use this medicine cautiously in patients suffering from Parkinson's disease.

Daily Dose

Your daily intake of Tilstigmin Tablet should be as specified by your doctor. The dosage may be updated according to the severity of your symptoms and your body's response to the medicine. It is crucial to adhere to the prescribed dosage and not alter it without speaking to your doctor.

Over Dose

In case of an accidental overdose, you might experience symptoms like nausea, diarrhoea, increased saliva production, or muscle twitching. If you notice any of these signs, it's essential that you inform your doctor.

Missed Dose

If you forget to take Tilstigmin Tablet at the usual time, have it as soon as you remember. However, if it's time for the next dose already, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Ensure to store Tilstigmin Tablet in a secure, tight container to guard it from air exposure.
Protect Tilstigmin Tablet from direct light and moisture to maintain its effectiveness.
Always keep the medicine out of reach of children for safety purposes.
Make it a point to use the medicine before its expiry date for optimal results.

If you're managing myasthenia gravis with Tilstigmin Tablet, consider incorporating regular, gentle exercise into your routine. It can help improve muscle strength and reduce fatigue.
For those using Tilstigmin Tablet for urinary retention or paralytic ileus, maintaining proper hydration is crucial. Drinking plenty of fluids can help keep your urinary and digestive systems functioning smoothly.

Fact Box

Drug Category	Cholinesterase Inhibitor
Therapeutic Category	Neuromuscular Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Myasthenia Gravis, Paralytic Ileus, Urinary Retention

What is Tilstigmin Tablet used for?

Tilstigmin Tablet is used to manage conditions like muscle weakness, intestinal paralysis, postoperative urinary retention, and normalising intestinal movements.

How does Tilstigmin Tablet work?

It works by increasing a neurotransmitter called acetylcholine, which aids in the communication between nerves and muscles, thus managing muscle weakness and contractions.

Can I take Tilstigmin Tablet with food?

You must take the medicine as directed by your doctor.

What are the side effects of Tilstigmin Tablet?

Common side effects include nausea, vomiting, diarrhoea, abdominal cramps, increased salivation and sweating. If you notice severe reactions, consult your doctor immediately.

Can I use Tilstigmin Tablet if I am pregnant or breastfeeding?

Use during pregnancy or breastfeeding should be done only if clearly necessary. As this medicine is excreted in breast milk, caution is advised.

Are there any precautions while using Tilstigmin Tablet?

Yes, use cautiously if you have asthma, seizures, hyperthyroidism or peptic ulcer. Also inform your doctor about any other medical conditions or medicines you take.

How should I store my Tilstigmin Tablets?

Store your tablets in a tight, light-resistant container. Keep them out of reach of children and protect from moisture and direct light.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

17/3rt, S R Nagar, S R Nagar, near Andhra Bank, Hyderabad, Telangana 500038

Country of origin: INDIA

References

FULL PRESCRIBING INFORMATION: CONTENTS* 1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION 2.1 Important Dosage and Administration Instructions 2.2 Recommended Dosage in Adults 2.3 Recommended Dosage in Pediatric Patients, including Neonates 2.4 Concomitant or Pre-Administration of Anticholinergic Agents 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS 5 WARNINGS AND PRECAUTIONS 5.1 Bradycardia 5.2 Cardiovascular. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/203629s003lbl.pdf
(2024). Oup.com. https://academic.oup.com/ajhp/article-abstract/70/14/1184/5112219
NCATS Inxight Drugs — NEOSTIGMINE BROMIDE. (2019). Ncats.io. https://drugs.ncats.io/drug/005SYP50G5
Neostigmine: Uses, Interactions, Mechanism of Action | DrugBank Online. (2021). Drugbank.com; DrugBank. https://go.drugbank.com/drugs/DB01400
NEOSTIGMINE AND NEUROMUSCULAR DYSFUNCTION. (1945). Journal of the American Medical Association, 128(11), 812–812. https://doi.org/10.1001/jama.1945.02860280038010

Was this product description useful?

29 people find this information helpful

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

Quick links

Uses
Directions for Use
Route of Administration
Side Effects
Medicine Activity
Precautions & Warnings
Interactions
Dosage
Storage
Diet & Lifestyle
Fact Box
FAQs

Health Articles

View All

Food & Nutrition

Top 8 Health Benefits Of Eating Celery

Home Remedies

What Causes Shortness of Breath? Home Remedies for Relief

Bones & Muscle Care

Home Remedies for Neck Pain: Fast Relief and Treatment Options

Disease Management

What You Should Know About Types and Degrees of Burns

Food & Nutrition

Canola Oil: Uses, Benefits and Side Effects

Home Remedies

How to Manage Indigestion With Simple Home Remedies

Women's Health

Effective Home Remedies to Get Periods

Women's Health

Natural Ways to Increase Breast Size Safely

Yoga

Bhramari Pranayama (Bee Breath): Benefits and Steps

Weight management

Different Weight Loss Exercises or Fat Loss Workout

Yoga

Padmasana (Lotus Position): Types, Step-by-Step Guide, Benefits and Precautions

Yoga

Benefits of Chakrasana and How to Do It

Company

About Us Health Article Diseases & Health Conditions All Medicines Need Help FAQ

Social

Legal

Terms & Conditions Privacy Policy Editorial Policy Returns & Cancellations

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.