Tacroz Forte 01 Ointment 20 Gm

Tacroz Forte Ointment 20gm

Glenmark Pharmaceuticals Ltd.

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Composition

Tacrolimus (0.1 %)

Tacroz Forte Ointment is primarily used to manage moderate to severe atopic dermatitis, commonly known as eczema. This medicine is part of a group of medicines known as macrolide calcineurin inhibitors.

This ointment is also used for the short-term and intermittent long-term management of eczema symptoms in adults and children over 2 years old, especially when conventional therapies like topical corticosteroids have not worked or caused side effects. The ointment helps manage inflammatory symptoms such as itching, redness and skin lesions.

You should apply this medicine as directed by your doctor. It's important that you inform your doctor about any pre-existing conditions or ongoing medications before beginning this medicine. If you notice any side effects while using this medicine, notify your doctor immediately. Ensure that you continue applying the ointment for the duration prescribed by your doctor for optimal results.

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Tacroz Forte Ointment is used for the following:

Managing moderate to severe atopic dermatitis or eczema in adults and children aged 2 years and above.
Relief from inflammatory symptoms of eczema such as itching, redness, and skin lesions.
Use as a second-line option when initial treatments like topical corticosteroids are ineffective or cause side effects.

Directions for Use of Tacroz Forte Ointment 20gm

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Tacroz Forte Ointment is applied topically.

Side Effects of Tacroz Forte Ointment 20gm

Tacroz Forte Ointment may cause the following side effects:

Burning sensation at the application site
Skin soreness
Itching and redness of skin.
Flu-like symptoms
Acne
Folliculitis

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Tacroz Forte Ointment. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Burning sensation at the application site: Apply Tacroz Forte Ointment on cool skin, rather than immediately after a warm shower or bath.
Itching and redness of skin: Avoid hot showers and harsh soaps after applying the ointment.

Tacroz Forte Ointment contains tacrolimus (0.1 %), which acts on the body in the following ways:

Inhibiting T-cell activation: Tacrolimus works by blocking a particular enzyme in your body called calcineurin phosphatase. This enzyme plays a significant role in activating T-cells, which are a key component of your immune system.
Reducing Inflammation: By inhibiting T-cell activation, tacrolimus effectively manages the immune response that triggers symptoms of eczema such as redness, itching and skin lesions.
Suppressing Production of Inflammatory Cytokines: Tacrolimus also disrupts the production of inflammatory cytokines like interleukin-2 by preventing their transcription factor from functioning properly. These cytokines are substances that can cause inflammation and other immune responses, so suppressing them helps manage eczema symptoms.

Pregnancy

If you are pregnant or planning to conceive, caution is advised when considering Tacroz Forte Ointment. It is best to consult your doctor before using this medicine.

Breastfeeding

For breastfeeding women, use of Tacroz Forte Ointment should be discussed with your doctor to understand the potential risks and benefits.

Alcohol

Alcohol consumption might cause facial flushing or skin redness when applying Tacroz Forte Ointment. It is advisable to limit alcohol intake during the course of this medication.

Liver

As this is a topical ointment, liver health concerns rarely apply. However, if you have a history of liver problems, it's always wise to discuss this with your doctor.

Kidney

Kidney health considerations are generally not relevant for topical applications like Tacroz Forte Ointment. But if you have any kidney health issues, it's prudent to consult your doctor beforehand.

Using Machines & Driving

Tacroz Forte Ointment is a topical application and unlikely to affect your ability to drive or operate machinery.

Allergy

This medicine is not suitable for individuals with a known hypersensitivity to Tacrolimus or any other ingredients in the formulation. Ensure you discuss any known allergies with your doctor before using this ointment.

Children

Tacroz Forte Ointment can be used on children under medical supervision and is not recommended for infants younger than 2 years.

Older Patients

Older patients can use Tacroz Forte Ointment under medical supervision. Age-related concerns like liver and kidney health issues should be discussed with the doctor prior to use.

Interactions of Tacroz Forte Ointment 20gm

Drug-Drug Interactions

Tacroz Forte Ointment interacts with the following medicines:

Topical Corticosteroids: Using Tacroz Forte Ointment concurrently with topical corticosteroids like hydrocortisone may enhance the local immunosuppressive effects, increasing the risk of skin infections.
Systemic Immunosuppressants (e.g., Cyclosporine): Tacroz Forte Ointment when used with systemic immunosuppressants can increase overall immunosuppression, leading to higher infection risks.
Other Topical Medications (e.g., Emollients): Applying other topical medications or emollients like petrolatum can alter the absorption of Tacroz Forte Ointment.

Drug-Food Interactions

There are no known specific food interactions with Tacroz Forte Ointment.

Drug-Disease Interactions

Tacroz Forte Ointment interacts with Netherton's Syndrome. If you have this skin condition, exercise caution while using Tacroz Forte Ointment as it could potentially worsen your condition.

Daily Dose

You should apply Tacroz Forte Ointment as prescribed by your doctor. The dosage may vary depending on the severity of your condition and your response to the ointment.

Over Dose

Applying more Tacroz Forte Ointment than recommended may cause local skin reactions like burning, stinging, or itching. If these symptoms persist, please consult your doctor.

Missed Dose

If you miss applying Tacroz Forte Ointment, do so as soon as you remember. However, if it's nearly time for your next application, skip the missed one.

Store Tacroz Forte Ointment at room temperature, below 25°C.
Keep it away from direct heat, light and moisture.
Do not refrigerate the ointment.
Always keep it out of reach of children.
Make sure to use it before the expiry date mentioned on its packaging.

Try to maintain a balanced diet rich in essential fatty acids, which can help manage eczema. Foods like nuts, seeds, avocados, and fatty fish are beneficial.
Regular exercise can help reduce stress and improve overall health, which in turn may help manage eczema symptoms. Ensure you or your child partake in regular physical activities as suitable for your age and health conditions.

Fact Box

Drug Category	Immunosuppressant
Therapeutic Category	Dermatological Agent
Available Dosage Types	Ointment
Habit Forming	No
Ailment	Atopic Dermatitis, Eczema

Is Tacroz Forte Ointment a type of steroid?

No, Tacroz Forte Ointment is not a steroid. It contains tacrolimus, an immunosuppressant, which works differently than steroids.

Can I apply Tacroz Forte Ointment on the face?

Yes, you can apply it on facial skin affected by eczema, but avoid contact with the eyes and mouth.

How long does it take for Tacroz Forte Ointment to show results?

Generally, you may see improvement in 1-2 weeks, but it may take up to 6 weeks in some cases.

Will using Tacroz Forte Ointment thin my skin?

Unlike steroids, tacrolimus ointment does not cause skin thinning or atrophy, even with long-term use.

What should I do if I forget to apply a dose of Tacroz Forte Ointment?

Apply as soon as you remember. If it's nearly time for the next dose, skip the missed one and continue your regular schedule.

Can I drink alcohol while using Tacroz Forte Ointment?

Consuming alcohol during treatment may cause skin or facial flushing. It is advisable to limit your alcohol intake.

Can other topical creams be used along with Tacroz Forte Ointment?

Avoid using other topical medications on the same skin area unless advised by your doctor.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Glenmark House, HDO-Corporate Building, Wing-A, B.D. Sawant Marg, Chakala Off. Western Express Highway, Andheri (East), Mumbai, Maharashtra, 400099 India

Country of origin: INDIA

References

Tacrolimus: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00864
Tacrolimus topical: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a602020.html
Ohtsuki, M., Morimoto, H., & Nakagawa, H. (2018). Tacrolimus ointment for the treatment of adult and pediatric atopic dermatitis: Review on safety and benefits. Journal of Dermatology, 45(8), 936–942.https://pubmed.ncbi.nlm.nih.gov/29927498/
Streptomyces tsukubaensis. (n.d.). PROTOPIC ointment 0.03% and 0.1% - Prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/050777s018lbl.pdf

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