Tacrotopic 003 Ointment 10 Gm

Tacrotopic 0.03% Ointment 10gm

Elder Pharmaceuticals Ltd

Tube of 10 GM

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MRP ~~₹154.4~~

₹126.61

₹15.44/GM

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Store Below 30^o C

Composition

Tacrolimus (0.03 %)

Strength:

0.1 %0.03 %

Tacrotopic 0.03% Ointment 10gm is primarily used for managing moderate-to-severe atopic dermatitis, commonly known as eczema. This medicine falls under the category of immunosuppressive agents, specifically macrolide lactams.

In addition to its main use, this ointment can be employed when conventional therapies for atopic dermatitis have not shown adequate results or are not advisable due to potential side effects. Eczema is a chronic skin condition that leads to intense itching, redness, dryness and swelling, often resulting in cracking and oozing of the skin.

You're advised to apply this ointment as directed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any unusual side effects while using this ointment, notify your doctor promptly. For effective management of your condition, continue applying the ointment for the duration prescribed by your doctor.

Tacrotopic 0.03% Ointment 10gm is used for the following:

Managing moderate-to-severe atopic dermatitis in adults
Assisting those with atopic dermatitis who haven't responded well to conventional therapies
Providing relief for symptoms of intense itching, redness, and swelling associated with chronic atopic dermatitis
Aiding in the reduction of skin dryness, cracking, oozing, and crusting caused by atopic dermatitis

Directions for Use of Tacrotopic 0.03% Ointment 10gm

Here's how to apply Tacrotopic 0.03% Ointment 10gm correctly:

Ensure that the ointment area is clean and dry before application.
Apply a thin layer of the ointment gently to the affected skin area as prescribed by your doctor.
Rub the ointment gently and completely on the skin until it is fully absorbed.
Continue applying as advised by your doctor until signs of atopic dermatitis resolve.
If symptoms persist beyond 6 weeks or worsen, consult your doctor immediately.

Tacrotopic 0.03% Ointment 10gm is applied topically.

Side Effects of Tacrotopic 0.03% Ointment 10gm

Tacrotopic 0.03% Ointment 10gm might cause the following side effects:

Application site reaction
Acne
Skin tingling
Headache
An inflammation or infection of the hair follicles

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing Tacrotopic 0.03% Ointment 10gm. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Application site reactions: If you feel discomfort at the application site, try applying a cold compress to soothe the area.
Acne: Maintaining good skin hygiene can help manage acne; wash your face gently with mild soap and warm water twice daily.

How Tacrotopic 0.03% Ointment 10gm Works?

Tacrotopic 0.03% Ointment 10gm contains tacrolimus (0.03%), which acts on the body as follows:

Binding to FKBP-12: Tacrolimus first binds with an intracellular protein named FKBP-12.
Inhibition of Calcineurin: The complex formed by tacrolimus and FKBP-12 inhibits calcineurin, an enzyme that relies on calcium and calmodulin.
Prevention of NFAT Dephosphorylation: By inhibiting calcineurin, tacrolimus prevents dephosphorylation and translocation of NFAT (Nuclear Factor of Activated T-cells), a key component in the production of inflammatory cytokines.

Pregnancy

If you are pregnant or planning to conceive, discuss this with your doctor before starting Tacrotopic 0.03% Ointment 10gm.

Breastfeeding

The use of Tacrotopic 0.03% Ointment 10gm while breastfeeding has not been thoroughly studied. It is best to consult your doctor if you are lactating before using this medicine.

Alcohol

If you consume alcohol while using this medicine, you might experience a heat sensation or redness in your face. Talk to your doctor about any concerns.

Liver

Even though systemic absorption of Tacrotopic 0.03% Ointment 10gm is minimal, caution is advised if you have severe liver disease. Discuss your liver health with your doctor before using this medicine.

Kidney

As with liver health, the systemic absorption of Tacrotopic 0.03% Ointment 10gm into the bloodstream is quite low. However, if you have severe kidney problems, consult your doctor before applying this ointment.

Using Machines & Driving

Tacrotopic 0.03% Ointment 10gm application is unlikely to affect your ability to drive or use machines as it's a topical medication.

Allergy

Do not apply Tacrotopic 0.03% Ointment 10gm if you're allergic to tacrolimus or any other ingredients in the formulation. Always inform your doctor about any known allergies before starting this medicine.

Children

Tacrotopic 0.03% Ointment 10gm should not be used on children under 2 years of age. For children above 2, it's best to consult a doctor before application.

Older Patients

Older patients should use Tacrotopic 0.03% Ointment 10gm under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 due to potential liver and kidney issues. Your doctor will guide you based on your health status.

Interactions of Tacrotopic 0.03% Ointment 10gm

Drug-Drug Interactions

Tacrotopic 0.03% Ointment 10gm interacts with the following medicines:

Immunosuppressive agents: Medicines like corticosteroids (cortisone) could potentially enhance the immunosuppressive effects of Tacrotopic 0.03% Ointment 10gm.

Drug-Food Interactions

There are no known food interactions with Tacrotopic 0.03% Ointment 10gm. As it's applied topically, what you eat or drink isn't likely to affect the medication's action.

Drug-Disease Interactions

Tacrotopic 0.03% Ointment 10gm interacts with the following diseases:

Netherton's Syndrome: This skin disorder can weaken the skin barrier, possibly leading to increased absorption of Tacrotopic 0.03% Ointment 10gm.
Liver Disease: As tacrolimus is metabolised in the liver, patients with liver disease should use this ointment cautiously.
Severe Renal Impairment: Although systemic absorption is minimal, caution is advised in patients with severe renal impairment.

Dosage of Tacrotopic 0.03% Ointment 10gm

Daily Dose

The daily application of Tacrotopic 0.03% Ointment 10gm should be as directed by your doctor. This could vary based on factors like the severity of your condition and how you respond to the ointment. Always adhere to the prescribed dosage and don’t use more without consulting your doctor.

Over Dose

If you accidentally apply too much Tacrotopic 0.03% Ointment 10gm, you might experience some side effects such as skin redness or itching. In such cases, wash off the excess ointment gently with water. If symptoms persist, inform your doctor.

Missed Dose

If you miss an application of Tacrotopic 0.03% Ointment 10gm, apply it as soon as you remember. But if it's almost time for your next scheduled application, simply skip the missed one and continue with your regular schedule. Never increase the number of applications without consulting your doctor.

Store Tacrotopic 0.03% Ointment 10gm at room temperature below 30°C.
Keep away from direct sunlight and heat.
Do not be exposed to moisture or excessively dry conditions.
Keep out of reach of children.

Regularly moisturise your skin, as dryness can intensify itching and inflammation associated with atopic dermatitis.
Avoid food allergens known to trigger or worsen your eczema symptoms; common ones include dairy products, eggs, nuts and seeds, wheat and gluten.

Fact Box

Drug Category	Immunosuppressive Agent
Therapeutic Category	Dermatological Medicine
Available Dosage Types	Ointment
Habit Forming	No
Ailment	Atopic Dermatitis, Eczema

What is Tacrotopic 0.03% Ointment 10gm used for?

Tacrotopic 0.03% Ointment 10gm is used to manage moderate-to-severe atopic dermatitis or eczema in adults who have not responded well to other therapies.

How does Tacrotopic 0.03% Ointment 10gm work?

Tacrolimus, the active ingredient, works by suppressing the immune response that causes inflammation and symptoms in atopic dermatitis or eczema.

Can Tacrotopic 0.03% Ointment 10gm be used on children?

Yes, Tacrotopic 0.03% Ointment 10gm can be used on children aged 2 years and older with a doctor's advice.

Is Tacrotopic 0.03% Ointment 10gm safe for long-term use?

Consult your doctor before using this medicine long-term.

Can Tacrotopic 0.03% Ointment 10gm be used on the face?

Yes, if affected by atopic dermatitis and advised by the doctor. Avoid contact with eyes and mucous membranes.

Does Tacrotopic 0.03% Ointment 10gm cause skin thinning like steroids?

No, unlike topical corticosteroids, Tacrotopic 0.03% Ointment 10gm does not cause skin atrophy or thinning with prolonged use.

How long does it take for Tacrotopic 0.03% Ointment 10gm to work?

Improvement in atopic dermatitis symptoms is usually seen within 1 week of starting treatment, with maximal benefits after 6 weeks of continuous use.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Elder House, Plot No C-9, Dalia Industrial Estate,,Off Veera Desai Road, Mumbai , Maharashtra- 400058

Country of origin: INDIA

References

Tacrolimus: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00864
Tacrolimus topical: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a602020.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 445643, Tacrolimus. Retrieved June 15, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Tacrolimus
Martins, J. C., Martins, C., Aoki, V., Gois, A. F., Ishii, H. A., & Da Silva, E. M. (2015). Topical tacrolimus for atopic dermatitis. Cochrane Library, 2016(10). https://pubmed.ncbi.nlm.nih.gov/26132597/
Araya, A. A., & Tasnif, Y. (2023, May 29). Tacrolimus. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK544318/

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