Tacmus 1 Mg Capsule 10

Tacmus 1 MG Capsule 10

Vhb Life Sciences Limited

Pack of 10 Units

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MRP ~~₹345~~

₹282.9

₹34.50/Units

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Composition

Tacrolimus (1 Mg)

Tacmus 1 MG Capsule 10 is primarily used to manage the risk of organ rejection in patients who have undergone kidney, liver, or heart transplants. This medication is part of a group known as immunosuppressants.

It aids in controlling immune responses that might lead to organ rejection. When used as part of a broader treatment regimen, it can help ensure the successful transplantation and functioning of the new organ in your body.

Before starting on this medicine, it's wise to consult your doctor about your dosage and schedule. Remember to inform your doctor about any other health conditions or medicines you are currently taking. If you observe any side effects while using this medicine, inform your doctor immediately. For best results, continue taking the medicine for the full duration prescribed by your doctor.

Tacmus 1 MG Capsule 10 is used for the following health conditions:

Preventing organ rejection in liver and kidney transplant patients.
Preventing organ rejection in heart transplant patients.

Directions for Use of Tacmus 1 MG Capsule 10

To use Tacmus 1 MG Capsule 10 correctly, follow these instructions:

Swallow the capsule whole with a glass of water.
Do not break, crush, or chew the capsule.
Always take this medicine as prescribed by your doctor.
Consult your doctor for specific advice tailored to your health condition and medication schedule.

Tacmus 1 MG Capsule 10 is taken orally.

Tacmus 1 MG Capsule 10 may have the following common side effects:

Diarrhoea
Hypertension
Nausea
Constipation
Abdominal pain
Tremor: Involuntary, rhythmic muscle contractions leading to shaking movements in one or more parts of your body.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Tacmus 1 MG Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Tacmus 1 MG Capsule 10 with food or milk to lessen this effect.
Nausea: If you feel nauseated, consider taking this medicine after meals to reduce discomfort.

Tacmus 1 MG Capsule 10 contains tacrolimus (1 mg), which contributes to its action in your body as follows:

Binding with FKBP-12: Tacrolimus forms a complex with an intracellular protein called FKBP-12.
Inhibiting Calcineurin: The tacrolimus-FKBP-12 complex then inhibits a calcium-dependent enzyme called calcineurin.
Suppressing T Cell activation: By inhibiting calcineurin, tacrolimus suppresses the activation of T cells, which are crucial components of the immune system.
Reducing Cytokine gene expression: The suppression of T cell activation leads to a reduction in cytokine gene expression. Cytokines are proteins that play a pivotal role in cell signalling during immune responses.
Preventing organ rejection: By suppressing immune reactions at the cellular level, tacrolimus helps prevent the body from rejecting transplanted organs.

Pregnancy

According to animal studies, Tacmus 1 MG Capsule 10 may cause harm to the developing baby. If you are pregnant, it's best to consult your doctor before taking this medicine.

Breastfeeding

Tacrolimus, the active ingredient in Tacmus 1 MG Capsule 10, is present in human milk and can have serious adverse effects on nursing infants. It's advised not to breastfeed while taking this medicine.

Alcohol

There is no specific information available about the interaction of Tacmus 1 MG Capsule 10 with alcohol. However, caution is always advised. Consult your doctor if you have any concerns.

Liver

Tacmus 1 MG Capsule 10 is metabolised by the liver. If you have liver health issues, discuss them with your doctor before starting this medicine.

Kidney

This medicine can affect kidney function. Caution is advised before using Tacmus 1 MG Capsule 10 if you have a history of kidney problems. It's best to consult your doctor before taking this medicine.

Using Machines & Driving

No specific information is available about the impact of Tacmus 1 MG Capsule 10 on your ability to drive or operate machinery. Always be cautious, and if you feel unwell or dizzy, avoid these activities.

Allergy

Tacmus 1 MG Capsule 10 should not be taken if you are allergic to tacrolimus or any other component of the product. If you have any known allergies, discuss them with your doctor before starting this medicine.

Children

The safety and efficacy of Tacmus 1 MG Capsule 10 have been established for certain transplant patients from the age of 2 years. However, caution is advised while giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

No significant differences have been observed between elderly and younger patients using Tacmus 1 MG Capsule 10. However, older patients should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tacmus 1 MG Capsule 10 interacts with the following medicines:

CYP3A4 inhibitors: Medicines like bromocriptine, clarithromycin, and diltiazem can increase tacrolimus blood levels, potentially aggravating side effects.
CYP3A4 inducers: Medicines such as carbamazepine, phenobarbital, and rifampin can decrease tacrolimus levels, potentially reducing its effectiveness.

Drug-Food Interactions

Certain foods may interact with Tacmus 1 MG Capsule 10:

Grapefruit juice: Consuming grapefruit juice while taking this medicine may increase tacrolimus levels in the blood, potentially enhancing side effects.

Drug-Disease Interactions

Tacmus 1 MG Capsule 10 interacts with the following diseases:

Hypertension: High blood pressure may worsen when taking this medicine due to its potential to cause elevated blood pressure.
Diabetes: This medication could affect blood sugar control, necessitating close monitoring of glucose levels.
Liver disease: Liver function may affect how this medicine works. Therefore, individuals with liver disease should use it cautiously.

Daily Dose

Your doctor will prescribe the exact daily dosage of Tacmus 1 MG Capsule 10 based on your individual needs. Factors such as the severity of your condition and your response to treatment will be considered. Always follow the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, read the package insert.

Over Dose

In case of an overdose, you may experience symptoms such as headache, shaking, or changes in mental status. If you have taken more than the prescribed dose of Tacmus 1 MG Capsule 10, do not panic but inform your doctor about it.

Missed Dose

If you forget to take a dose of Tacmus 1 MG Capsule 10, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.

Store Tacmus 1 MG Capsule 10 in a cool, dry place at a temperature below 30°C.
Don't expose the medicine to excessive light or moisture.
Keep it out of reach of children.
Always use this medicine before its expiry date.

Since Tacmus 1 MG Capsule 10 is used for managing organ rejection after transplantation, it's crucial to follow a balanced diet rich in proteins and low in salt and fat to support overall health and organ function.
Remember to avoid exposure to sunlight and ultraviolet light, as this medicine increases your risk of skin cancer. Wear protective clothing and use sunscreen when outdoors.

Fact Box

Drug Category	Calcineurin Inhibitor
Therapeutic Category	Immunosuppressant
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Organ Rejection Prophylaxis

What is Tacmus 1 MG Capsule 10?

Tacmus 1 MG Capsule 10 is an immunosuppressant medicine that contains tacrolimus. It helps to prevent organ rejection in adults who have had a transplant.

How does Tacmus 1 MG Capsule 10 work?

It works by reducing the activity of your immune system, specifically T lymphocytes, to prevent it from attacking the transplanted organ.

How should I take Tacmus 1 MG Capsule 10?

Take the capsule as prescribed by the doctor. Remember to swallow it whole without chewing or crushing it.

Can I take this medicine with food?

Food can decrease the rate at which tacrolimus is absorbed into your body. Consult your doctor for personalised advice on when to take it.

What precautions should I take while on Tacmus 1 MG Capsule 10?

Limit exposure to sunlight and UV light, monitor your blood glucose levels and blood pressure, and avoid live vaccines while taking this medicine.

Are there any side effects of Tacmus 1 MG Capsule 10?

Yes, common side effects include abnormal kidney function, high blood pressure, nausea, tremors, constipation and headaches, among others. Consult your doctor if the side effects persist.

Does Tacmus 1 MG Capsule 10 interact with other medicines?

Yes, it can interact with many medicines such as bromocriptine, clarithromycin, erythromycin, and carbamazepine. Always consult your doctor before starting any new medication.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

50 Ab,Government(erstwhile Kandivali Co Operative) Industrial Estate, Charkop Kandivali (W), Mumbai Mumbai City Mh 400067 In.

Country of origin: INDIA

References

MedlinePlus. (n.d.). Tacrolimus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601117.html
U.S. Food and Drug Administration. (2018). Clinical Pharmacology and Biopharmaceutics Review(s). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/210115Orig1s000ClinPharmR.pdf
Iwasaki K: Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics. Drug Metab Pharmacokinet. 2007 Oct;22(5):328-35. https://go.drugbank.com/articles/A38786
Tacrolimus.
https://pubchem.ncbi.nlm.nih.gov/compound/Tacrolimus
U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf

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