Ran Cv 500 Mg Tablet Er 10

Rancv 500 Tablet 10

Msn Laboratories Ltd

Strip of 10 Units

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MRP ~~₹128.3~~

₹105.21

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Composition

Ranolazine (500 Mg)

Strength:

500 MG 1000 MG

Rancv 500 Tablet is primarily used for managing chronic angina pectoris, a type of chest pain. This medicine falls within the anti-anginal class of medications.

Apart from its main use, this tablet also enhances the heart's efficiency in utilising oxygen. This allows the heart to perform more work with less oxygen, preventing new angina attacks and increasing exercise capacity. It does not, however, stop an ongoing acute angina attack.

As with any medicine, it's crucial to take this medication as directed by your doctor. Before starting on this medication, make sure to inform your doctor about any pre-existing conditions and ongoing medications you may be taking. If you experience any side effects while on this medicine, don't hesitate to inform your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Rancv 500 Tablet is used for the management of:

Chronic stable angina: This is a condition where you experience chest pain due to reduced blood flow to your heart.
Preventing new attacks of angina: The medication doesn't stop an existing attack but prevents new ones from occurring.
Increasing exercise capacity: It helps you carry out daily activities more easily by improving the efficiency of your heart's oxygen usage.

Directions for Use of Rancv 500 Tablet 10

Here's how you should take Rancv 500 Tablet:

Swallow the tablet whole with a glass of water.
Don't chew, crush, or break the tablet.
You may take it with or without food as per your comfort.
Remember to adhere strictly to the recommended dosage and not exceed it without consulting your doctor.
It's important not to stop this medicine abruptly without speaking to your doctor first.

Rancv 500 Tablet is taken orally.

Rancv 500 Tablet may have the following common side effects:

Dizziness
Headache
Constipation
Nausea
Weakness
Prolongation of the QT Interval on ECG: This could cause heart palpitations or fainting.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Rancv 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: Try to get up slowly when rising from a sitting or lying position.
Constipation: You could prevent this by drinking plenty of fluids and eating fibre-rich foods.

Rancv 500 Tablet contains ranolazine (500 mg) which interacts with the body in several ways:

Decreases late sodium current: Ranolazine works by reducing the late sodium current in heart muscle cells. This change helps the heart muscle relax and perform more efficiently.
Improves myocardial contractility and perfusion: By optimising sodium and calcium levels within heart cells, ranolazine enhances how well your heart muscles contract and improves blood supply to the heart muscle.
Alpha- and beta-adrenergic receptor blocking effects: Ranolazine also has some effects on alpha- and beta-adrenergic receptors in your body, contributing to its anti-anginal activity. The exact mechanism through which it achieves these effects is not fully understood yet.

Pregnancy

If you are pregnant, caution is advised while taking Rancv 500 Tablet. It is best to consult your doctor before starting this medicine.

Breastfeeding

While breastfeeding, it's recommended to exercise caution with Rancv 500 Tablet. Please discuss with your doctor to understand the potential risks and benefits.

Alcohol

You should avoid consuming alcohol while on Rancv 500 Tablet, as it might increase the risk of side effects such as dizziness and confusion.

Liver

Caution is needed when taking Rancv 500 Tablet if you have mild liver impairment. This medicine should not be used if you have severe liver diseases. In case of any liver health issues, consult your doctor before starting this medication.

Kidney

If you have a history of kidney problems, it's crucial to be cautious before using Rancv 500 Tablet. Please consult your doctor before starting this medication.

Using Machines & Driving

Rancv 500 Tablet can cause dizziness. Hence, avoid driving or operating heavy machinery until you know how this medication affects you.

Allergy

Rancv 500 Tablet is contraindicated if you have a known hypersensitivity to ranolazine or any other components of the tablet. If you have allergies, discuss them with your doctor before starting this medicine.

Children

Rancv 500 Tablet is not recommended for use in children under the age of 18 years. Always consult your doctor before giving any medicine to a child.

Older Patients

If you are above 70 years old, take Rancv 500 Tablet under medical supervision as you may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Rancv 500 Tablet interacts with the following medicines:

Moderate CYP3A inhibitors: Medicines like diltiazem, verapamil, erythromycin, and fluconazole may intensify the effect of ranolazine, therefore dose adjustments may be necessary.
P-gp inhibitors: Medications such as cyclosporine can increase the level of ranolazine in your body, thus requiring dose reduction.
Statins and cardiac glycosides: Rancv 500 Tablet can increase the levels of simvastatin and digoxin in your body, so combining these medications should be done cautiously.
Medicines metabolised by CYP2D6: Ranolazine can enhance the effects of medicines like metformin which are metabolised by CYP2D6.

Drug-Food Interactions

Grapefruit products can increase the levels of ranolazine in your body.

Drug-Disease Interactions

Rancv 500 Tablet interacts with the following diseases:

Severe renal impairment: Dose adjustments may be needed for patients with severe renal impairment.
Hepatic impairment: Rancv 500 Tablet should not be used in patients with clinically significant hepatic impairment.
QT prolongation: Patients with a history of QT prolongation should exercise caution due to the risk of ventricular arrhythmias.
Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption: These patients should avoid Rancv 500 Tablet as it contains lactose.

Daily Dose

Take Rancv 500 Tablet as directed by your doctor. The dosage can vary based on the severity of your condition and your response to the medication. Always adhere to the prescribed dosage and never increase it without consulting your doctor.

Over Dose

If you have accidentally taken more than the prescribed dose of Rancv 500 Tablet, you may experience severe dizziness, nausea, and confusion. Consult your doctor if these symptoms persist or worsen.

Missed Dose

If you miss a dose of Rancv 500 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Rancv 500 Tablet in a secure, closed container, away from direct light and moisture.
Keep the temperature below 30°C.
Avoid locations with extreme temperature fluctuations.
Ensure the medicine is out of reach of children.
Always check the expiry date before use.

Engage in regular, moderate physical activity like walking or cycling, which can improve heart health and help manage chronic angina.
Stick to a balanced diet low in saturated fats and high in fruits and vegetables. This can aid heart function and may help reduce angina symptoms.

Fact Box

Drug Category	late sodium current inhibitor
Therapeutic Category	anti-anginal
Available Dosage Types	Tablet
Habit Forming	No
Ailment	chronic stable angina

What is Rancv 500 Tablet used for?

Rancv 500 Tablet is used to manage chronic stable angina, a kind of chest pain. It improves the heart's efficiency of using oxygen, reducing anginal episodes.

How does Rancv 500 Tablet work?

Rancv 500 Tablet works by decreasing the late sodium current in heart cells, reducing calcium overload during inadequate blood flow, helping the heart muscle relax.

Can I crush or chew Rancv 500 Tablet?

No, Rancv 500 Tablet should be swallowed whole. Crushing or chewing can interfere with its extended-release properties and affect how it works.

What are the common side effects of Rancv 500 Tablet?

Common side effects include dizziness, headache, constipation, nausea, and weakness. These usually improve as your body adjusts to the medication.

Are there any contraindications for taking Rancv 500 Tablet?

Yes, avoid taking Rancv 500 Tablet if you're allergic to ranolazine or any tablet components, or if you're taking strong CYP3A inhibitors or inducers.

What precautions should I take while using Rancv 500 Tablet?

Use caution if you have a history of QT prolongation, low blood pressure, liver or kidney disease, or electrolyte disturbances. Always consult your doctor.

Can Rancv 500 Tablet interact with other medicines?

Yes, it may interact with several medications like diltiazem, verapamil, erythromycin and fluconazole among others. Always inform your doctor about all medicines you're taking.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad, Telangana 500018

Country of origin: INDIA

References

CV Therapeutics. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021526s007lbl.pdf
DailyMed - RANOLAZINE- extended-release tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f0cbc60a-5ef0-4ba9-9863-b065360bca21
Ranolazine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00243
Ranolazine: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a606015.html

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