Pyrimide 50 Mg Suspension 60 Ml

Pyrimide 50 MG Suspension 60 ML

Alkem Laboratories Ltd.

Bottle of 60 ML

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MRP ~~₹12.48~~

₹10.23

₹0.21/ML

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Prescription required for this medicine

Store Below 30^o C

Composition

Nimesulide (50 Mg)

Pyrimide 50 MG Suspension 60 ML is used primarily to manage acute pain, inflammation, and fever in children. This oral medicine is part of a group of medications known as non-steroidal anti-inflammatory drugs (NSAIDs).

In addition to its primary use, this suspension can also help manage inflammation associated with conditions like sore throat, tonsillitis, laryngitis, ear infections, dental pain, headache, and post-immunization pyrexia. It provides symptomatic relief of pain and fever while reducing inflammation.

Before your child begins taking this medicine, it's important you inform your doctor about any pre-existing conditions or ongoing medicines that your child might be on. If you notice any severe side effects while your child is on this medicine, notify your doctor immediately. Continue giving the medicine for the duration prescribed by your doctor for optimal results.

Pyrimide 50 MG Suspension 60 ML is used for the following:

Managing acute pain and headache in children.
Controlling fever.
Relieving pain and inflammation from upper respiratory tract infections such as sore throat, tonsillitis, and laryngitis.
Alleviating discomfort from ear infections, specifically acute otitis media.
Easing dental pain and inflammation, particularly during teething.
Managing fever post-vaccination.

Directions for Use of Pyrimide 50 MG Suspension 60 ML

Shake the bottle well before each use.
Measure the exact quantity recommended by your doctor using a spoon or cup.
You can give this medicine to your child directly or mix it with a small quantity of food.
Give it after meals to reduce the chances of stomach upset.
If your child vomits within 30 minutes of taking a dose, you may repeat the same dose.
Always consult your doctor for specific advice on how to give this medicine.

Pyrimide 50 MG Suspension 60 ML is given orally to the child.

Side Effects of Pyrimide 50 MG Suspension 60 ML

While giving Pyrimide 50 MG Suspension 60 ML to your child, they may experience certain side effects. These include:

Abdominal pain
Nausea
Diarrhoea
Skin rash
Itching
Headache
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing Pyrimide 50 MG Suspension 60 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage common side effects:

Abdominal pain: Give the medicine after meals to reduce the chances of stomach upset.
Nausea: If your child feels nauseated, giving the medicine with a small amount of food might help.

How Pyrimide 50 MG Suspension 60 ML Works?

Pyrimide 50 MG Suspension 60 ML contains nimesulide (50 mg), which works on the body as follows:

Inhibits Cyclooxygenase-2 (COX-2): Nimesulide works by blocking an enzyme called COX-2 in your child's body. This enzyme plays a key role in producing pro-inflammatory chemicals called prostaglandins that are responsible for pain, fever, and inflammation.
Reduces Prostaglandins: By blocking the activity of COX-2, nimesulide effectively reduces the production of prostaglandins.
Scavenges free radicals: Nimesulide has some free radical scavenging activity, which helps neutralise harmful compounds in the body that can cause cell damage.

Pregnancy

Breastfeeding

Alcohol

Liver

Caution is advised while giving Pyrimide 50 MG Suspension 60 ML to children with mild to moderate liver impairment. It isn't recommended for severe liver diseases. Discuss any liver problems your child might have with your doctor before starting this medicine.

Kidney

Caution is advised before giving Pyrimide 50 MG Suspension 60 ML to children if they have a history of kidney problems. It's a good idea to consult your doctor before starting this medicine.

Using Machines & Driving

Allergy

Pyrimide 50 MG Suspension 60 ML should not be given if your child has known hypersensitivity to nimesulide or any of its components. Also, if your child has a history of NSAID-induced bronchospasm, urticaria, or anaphylaxis, this medicine should be avoided.

Children

Always consult your doctor before giving Pyrimide 50 MG Suspension 60 ML to children. Caution is advised, especially in children with asthma, renal or hepatic impairment, cardiac disease, coagulation disorders, and those on medications that increase the risk of bleeding.

Older Patients

Interactions of Pyrimide 50 MG Suspension 60 ML

Drug-Drug Interactions

Pyrimide 50 MG Suspension 60 ML interacts with the following medicines:

Anticoagulants: Medicines like warfarin and heparin may interact with Pyrimide 50 MG Suspension 60 ML, potentially increasing the risk of bleeding.
Selective serotonin reuptake inhibitors (SSRIs): When given with Pyrimide 50 MG Suspension 60 ML, SSRIs such as fluoxetine and citalopram can enhance the risk of gastrointestinal bleeding.
Corticosteroids: Medicines like prednisone or betamethasone can increase the risk of gastrointestinal ulcers or bleeding when given alongside Pyrimide 50 MG Suspension 60 ML.
Diuretics and antihypertensives: The effectiveness of medications like furosemide, hydrochlorothiazide or amlodipine might be reduced when given with Pyrimide 50 MG Suspension 60 ML.
Immunosuppressants: The use of cyclosporine or tacrolimus along with Pyrimide 50 MG Suspension 60 ML can increase the risk of kidney damage.

Drug-Food Interactions

Pyrimide 50 MG Suspension 60 ML has no known specific interactions with food.

Drug-Disease Interactions

Pyrimide 50 MG Suspension 60 ML interacts with the following diseases:

Liver disease: If your child has severely impaired liver function, giving them Pyrimide 50 MG Suspension 60 ML could worsen their condition.
Kidney disease: For children with severe kidney disease, this medicine might exacerbate their illness.
Heart failure: In cases of severe heart failure in children, the use of Pyrimide 50 MG Suspension 60 ML could potentially aggravate their health condition.
Coagulation disorders: Children with blood clotting disorders should be given this medication cautiously, as it can increase the risk of bleeding.

Dosage of Pyrimide 50 MG Suspension 60 ML

Daily Dose

The recommended dose of Pyrimide 50 MG Suspension 60 ML should be given to your child as directed by the doctor. The dose may vary depending on how severe your child's symptoms are and how they respond to the medicine. Always follow the doctor's instructions carefully and avoid exceeding the prescribed dose without consulting the doctor.

Over Dose

In case an extra dose of Pyrimide 50 MG Suspension 60 ML is accidentally given, your child might experience symptoms like vomiting, feeling sleepy, or a headache. If any of these effects persist or worsen, inform your doctor immediately.

Missed Dose

If you forget to give your child their dose of Pyrimide 50 MG Suspension 60 ML, give it as soon as you remember. However, if it’s nearly time for the next dose, skip the missed one and continue with your child's regular schedule. Never increase the dosage without consulting with the doctor.

Store Pyrimide 50 MG Suspension 60 ML in a cool, dry place, not exceeding 30°C.
Shield it from direct sunlight.
Keep it out of reach from children.
Always make sure to use the suspension before its expiry date.

When your child is taking Pyrimide 50 MG Suspension 60 ML for managing pain and fever associated with dental issues, ensure a soft diet that's easy to chew. This can help reduce discomfort during meals.
If Pyrimide 50 MG Suspension 60 ML is being used to manage pain and inflammation from respiratory tract infections, regularly using a humidifier in your child's room can help soothe their throat and ease breathing.

Fact Box

Drug Category	COX-2 Inhibitor
Therapeutic Category	Non-steroidal Anti-inflammatory
Available Dosage Types	Suspension
Habit Forming	No
Ailment	Upper Respiratory Tract Infections, Dental Pain

What is Pyrimide 50 MG Suspension 60 ML used for?

This medicine helps manage pain, fever, and swelling in children, especially linked with upper respiratory tract infections, dental problems, post-immunisation fever, and headaches.

How does Pyrimide 50 MG Suspension 60 ML work?

It contains an active ingredient called nimesulide, which inhibits a specific enzyme in the body, reducing the production of chemicals that cause pain, fever, and inflammation.

How should Pyrimide 50 MG Suspension 60 ML be given to my child?

The suspension can be given directly or mixed with food. Always shake the bottle well before use and use only the provided measuring cup.

What are the possible side effects of Pyrimide 50 MG Suspension 60 ML?

Common side effects may include stomach discomfort, skin rash, and headache. Rare but severe reactions could include ulcers, severe skin reactions or liver damage.

What precautions should I consider when giving my child Pyrimide 50 MG Suspension 60 ML?

Avoid if your child has severe kidney or liver problems, peptic ulcers, or allergies to any ingredients. Use cautiously in children with asthma or heart conditions.

Can Pyrimide 50 MG Suspension 60 ML interact with other medicines?

Yes, it can interact with medicines like blood thinners and corticosteroids, increasing bleeding risk. It may also affect the effectiveness of diuretics and also increase the level of certain medications in the body.

What if I accidentally give too much of Pyrimide 50 MG Suspension 60 ML to my child?

Overdose can lead to severe vomiting, abdominal pain and even liver damage. If this occurs, seek immediate medical help.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

Rainsford, K. D., Kean, W. F., & Ehrlich, G. E. (1993). Review of the pharmaceutical properties and clinical effects of the topical NSAID, nimesulide. Inflammopharmacology, 2(1), 3-30. Retrieved from https://pubmed.ncbi.nlm.nih.gov/7506175/ on 1 April 2024.
Medlineplus (2022). Nimesulide. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK547852/on 1 April 2024.
Nimesulide (Amendments to the Summary of Product Characteristics and Package Leaflet) (online) Available from: https://www.ema.europa.eu/en/documents/referral/nimesulide-article-107-procedures-annex-iii_en.pdf https://link.springer.com/article/10.1007/BF02723780
European Medicine Agency. Nimesulide. Available from: https://www.ema.europa.eu/en/medicines/human/referrals/nimesulide-1
Chandra J, Kumar Bhatnagar S. Antipyretics in children. Indian J Pediatr. 2002;69:69-74. https://link.springer.com/article/10.1007/BF02723780

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