Pyreflam 400325 Mg Tablet 100

Pyreflam 400/325 MG Tablet 100

Jawa Laboratories

Pack of 100 Units
Pack of 10 Units

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MRP ~~₹178.3~~

₹88.97

₹1.78/Units

50.1% off

*MRP inclusive of all taxes

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15 days Easy returns

Prescription required for this medicine

Store Below 30^o C

Composition

Ibuprofen (400 Mg) + Paracetamol/acetaminophen (325 Mg)

Pyreflam 400/325 MG Tablet 100 is primarily used to manage mild to moderate pain, reduce inflammation, and control fever. This combination medicine belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics.

In addition to its primary use, this tablet is also beneficial in relieving discomfort associated with conditions like headaches, muscle pain, menstrual cramps, toothaches, joint pain, backache, and symptoms of cold and flu. It plays a significant role in the short-term management of these conditions.

It's important to take this medicine as directed by your doctor. Inform your doctor about any pre-existing health condition or ongoing medication before you start taking this medicine. If you experience any side effects while taking this medicine, immediately consult your doctor. For optimal results, continue using the medicine for the duration prescribed by your doctor.

Pyreflam 400/325 MG Tablet 100 is used for the following:

Managing headache discomfort
Easing muscle pain
Providing relief from menstrual cramps
Alleviating toothache
Reducing joint pain
Relieving backache
Controlling symptoms associated with cold and flu
Lowering fever

Directions for Use of Pyreflam 400/325 MG Tablet 100

Consume the tablet orally with a glass of water.
Avoid breaking, crushing, or chewing the tablet.
Always take this medicine with food or milk to minimise possible stomach upset.
Never exceed the recommended dosage without consulting your doctor first.
Remember not to discontinue the medicine abruptly. Always consult your doctor before deciding to stop using it.

Pyreflam 400/325 MG Tablet 100 is taken orally.

Side Effects of Pyreflam 400/325 MG Tablet 100

Pyreflam 400/325 MG Tablet 100 may cause the following common side effects:

Heartburn
Indigestion
Nausea
Stomach pain
Diarrhoea
Constipation
Dizziness
Drowsiness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pyreflam 400/325 MG Tablet 100. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Heartburn: Try taking Pyreflam 400/325 MG Tablet 100 with food or milk to lessen this effect.
Drowsiness: Consider taking this medicine at night if it makes you feel sleepy during the day.

How Pyreflam 400/325 MG Tablet 100 Works?

Pyreflam 400/325 MG Tablet 100 comprises of two active ingredients:

Ibuprofen (400 mg): This component belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of prostaglandins. Prostaglandins are chemicals that cause pain, inflammation and fever in the body.
Paracetamol (325 mg): Although the exact mechanism of action is not entirely understood, paracetamol is believed to inhibit the synthesis of prostaglandins in the central nervous system. This action effectively reduces pain and fever. Additionally, paracetamol acts on the hypothalamus a part of your brain that controls body temperature thereby further managing fever.

Pregnancy

Pyreflam 400/325 MG Tablet 100 should be used with caution during pregnancy, especially in the third trimester. It is best to consult your doctor before taking this medicine.

Breastfeeding

The use of Pyreflam 400/325 MG Tablet 100 while breastfeeding should be discussed with your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol while taking Pyreflam 400/325 MG Tablet 100 is contraindicated as it may increase the risk of stomach bleeding and liver damage.

Liver

If you have liver problems, caution is advised when using Pyreflam 400/325 MG Tablet 100. Discuss these issues with your doctor before starting this medication, as it may affect liver function.

Kidney

Caution is recommended with Pyreflam 400/325 MG Tablet 100 if you have any history of kidney problems. It's advisable to consult your doctor before starting this medication.

Using Machines & Driving

Pyreflam 400/325 MG Tablet 100 may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how this medication affects you.

Allergy

This medication is contraindicated in patients who are allergic to ibuprofen, paracetamol, or any other components of Pyreflam 400/325 MG Tablet 100.

Children

Caution is advised while giving Pyreflam 400/325 MG Tablet 100 to children. Always consult your doctor before administering any medicine to a child.

Older Patients

Older patients should take Pyreflam 400/325 MG Tablet 100 under medical supervision as they might be more susceptible to its side effects and may also have liver or kidney issues. Your doctor will guide you based on your health status.

Interactions of Pyreflam 400/325 MG Tablet 100

Drug-Drug Interactions

Pyreflam 400/325 MG Tablet 100 interacts with the following medicines:

Anticoagulants: Medications like warfarin could have their blood-thinning effects amplified when taken with Pyreflam 400/325 MG Tablet 100, raising the chance of bleeding.
Other NSAIDs: When aspirin is consumed with Pyreflam 400/325 MG Tablet 100, it could increase the risk of stomach ulcers or bleeding.
Diuretics: Medicines such as furosemide and hydrochlorothiazide may have their efficacy reduced when taken concurrently with Pyreflam 400/325 MG Tablet 100.
Mood stabilizers: Taking lithium with Pyreflam 400/325 MG Tablet 100 might increase lithium levels in your blood, potentially leading to lithium toxicity.

Drug-Food Interactions

Pyreflam 400/325 MG Tablet 100 does not have any known significant interactions with specific foods.

Drug-Disease Interactions

Pyreflam 400/325 MG Tablet 100 reacts with the following diseases:

Stomach Ulcers or Bleeding: If you have a history of stomach ulcers or bleeding, using Pyreflam 400/325 MG Tablet 100 could worsen your condition.
Asthma: Asthmatics should be cautious while taking this medicine as it might exacerbate asthma symptoms.
Liver or Kidney Disease: Pyreflam 400/325 MG Tablet 100 should be used cautiously in patients with liver or kidney disease as it can escalate the strain on these organs.
Hypertension and Heart Disease: This medicine can cause fluid retention and swelling, potentially worsening hypertension and heart disease.

Dosage of Pyreflam 400/325 MG Tablet 100

Daily Dose

The recommended dose of Pyreflam 400/325 MG Tablet 100 should be taken as directed by your doctor. The dosage may vary based on factors like the severity of your condition and how you respond to the medicine. Always follow the prescribed dosage and never exceed it without talking to your doctor.

Over Dose

Exceeding the prescribed dose of Pyreflam 400/325 MG Tablet 100 could lead to common symptoms such as nausea, stomach pain, and dizziness. If you experience these or any other unusual symptoms, inform your doctor.

Missed Dose

If you forget to take your Pyreflam 400/325 MG Tablet 100, you should take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store Pyreflam 400/325 MG Tablet 100 at room temperature, ideally below 30°C.
Keep the medicine away from direct sunlight and moisture.
Ensure it is stowed in a dry place.
Always keep this medicine out of reach of children.
Use the product before its expiry date for maximum effectiveness.

Since Pyreflam 400/325 MG Tablet 100 manages pain and inflammation, drinking plenty of water can help flush out toxins and reduce inflammation in your body.
Regular, gentle exercise, such as walking or swimming, can help manage joint and muscle pain by keeping muscles strong and flexible.

Fact Box

Drug Category	Prostaglandin Inhibitor
Therapeutic Category	Non-steroidal Anti-inflammatory
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Headache, Muscle Pain, Fever

Can I take Pyreflam 400/325 MG Tablet 100 on an empty stomach?

To reduce the risk of stomach upset, it's recommended to take Pyreflam 400/325 MG Tablet 100 with food or milk.

Is long-term use of Pyreflam 400/325 MG Tablet 100 safe?

Pyreflam 400/325 MG Tablet 100 is intended for short-term use. If symptoms persist or worsen, please consult your doctor.

Can Pyreflam 400/325 MG Tablet 100 be used during pregnancy?

Avoid using this medicine during pregnancy, especially in the third trimester, unless advised by your doctor.

Is it safe to consume alcohol while taking Pyreflam 400/325 MG Tablet 100?

Combining alcohol with this medication may increase the risk of stomach bleeding and liver damage.

What should I do if I miss a dose of Pyreflam 400/325 MG Tablet 100?

If you miss a dose, take it as soon as you remember. Don't double the dose to make up for a missed one.

Can I take other painkillers along with Pyreflam 400/325 MG Tablet 100?

Always discuss with your doctor before starting any new medicine to avoid potential medicine interactions.

How should I store my Pyreflam 400/325 MG Tablet 100?

Store this medicine at room temperature, away from direct sunlight, heat, and moisture.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Head Office, Works & Admn. Office:129, Udyog Vihar Phase - IV , Gurgaon - 122015

Country of origin: INDIA

References

DailyMed. (n.d.). Ibuprofen Ibuprofen tablet. U.S. National Library of Medicine. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=c0fa1871-05d5-49a2-8695-f209652a3df8&type=display
MedlinePlus. (n.d.). Ibuprofen. U.S. National Library of Medicine. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a681004.html
U.S. Food and Drug Administration. (2005). Advil PM (Ibuprofen and Diphenhydramine) Capsules. U.S. Department of Health and Human Services. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2005/021393s000_Advil_PM_MedR.pdf
U.S. Food and Drug Administration. (2006). Label: Children’s Motrin (Ibuprofen) Oral Suspension, Infants’ Motrin (Ibuprofen) Oral Suspension, Motrin (Ibuprofen) Tablets. U.S. Department of Health and Human Services. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/040330s015,040341s013,040434s003lbl.pdf

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