Prd 30 40 Mg Capsule Pr 15

P Rd Capsule 15

Blue Cross Laboratories Ltd

Strip of 15 UNITS

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Composition

Domperidone (30 Mg) + Pantoprazole (40 Mg)

P-RD Capsule is primarily used to manage gastroesophageal reflux disease (GERD). This combination medicine is part of the class of medications known as gastrointestinal agents, which help regulate the functioning of the stomach and intestines.

In addition to its main use, this capsule is also beneficial for managing dyspepsia associated with delayed gastric emptying. Furthermore, it can help to manage nausea and vomiting caused by various factors.

It's important to take this medicine as directed by your doctor. Before you start taking this capsule, inform your doctor about any pre-existing conditions and current medications. If you notice any side effects while taking this medicine, notify your doctor immediately. Lastly, make sure you continue taking this medicine for the entire duration prescribed by your doctor for the best results.

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P-RD Capsule is used for managing the following health conditions:

Control of gastroesophageal reflux disease (GERD), a condition where stomach acid frequently flows back into the tube connecting your mouth and stomach, causing irritation.
Management of dyspepsia is linked with delayed gastric emptying, commonly known as slow digestion, which can cause feelings of fullness, discomfort, and bloating.
Relief from nausea and vomiting due to various causes, helping you feel better and promoting your overall wellbeing.

Here are some guidelines on how to take P-RD Capsule:

Swallow the capsule whole with a glass of water.
Make sure that you do not open, chew or crush the capsule.
Always take the capsule at least 30 minutes before a meal to allow it to work effectively.
Remember, it's important not to stop taking this medicine without first consulting your doctor.

P-RD Capsule is taken orally.

P-RD Capsule may have the following common side effects:

Headache
Dizziness
Diarrhoea
Abdominal pain
Flatulence
Rash
Gynecomastia: This is a condition where males develop enlarged breasts. It's rare but can happen.
Menstrual irregularities: Some females might notice changes in their menstrual cycle.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of P-RD Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking P-RD Capsule with food.
Abdominal pain: Consider taking this medicine at night if it causes you stomach pain during the day.

P-RD Capsule contains two active ingredients:

Domperidone (30 mg): This ingredient works by blocking a receptor in your body called dopamine-2 (D2) receptor. This action speeds up the emptying of your stomach and prevents stomach contents from flowing back into the oesophagus. Domperidone also helps to manage nausea and vomiting by blocking D2 receptors in a part of your brain known as the chemoreceptor trigger zone.
Pantoprazole (40 mg): This component is a proton pump inhibitor (PPI). It works by permanently disabling a system in your stomach cells known as the H+/K+ ATPase enzyme system. This action suppresses the final stage of acid production in your stomach. As a result, there's a significant and long-lasting decrease in gastric acid secretion, which gives time for the oesophagus and stomach lining to heal.

Pregnancy

Caution is advised while taking P-RD Capsule if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, you should discuss with your doctor before using P-RD Capsule.

Alcohol

While taking P-RD Capsule, it is advisable to limit your alcohol intake as it can worsen certain side effects and potentially reduce the effectiveness of the medicine.

Liver

P-RD Capsule should be used with caution in patients with mild to moderate liver impairment and not recommended for severe liver diseases. If you have any liver problems, discuss them with your doctor before starting P-RD Capsule.

Kidney

If you have a history of kidney problems, it's a good idea to consult your doctor before taking P-RD Capsule.

Using Machines & Driving

If you experience dizziness or any adverse effects that could affect your ability to concentrate or react, refrain from driving or operating machinery until you feel well again.

Allergy

If you are allergic to domperidone, pantoprazole, substituted benzimidazoles, or any other ingredients of the P-RD Capsule, avoid taking this medicine.

Children

P-RD Capsule is not recommended for children below 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take P-RD Capsule under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

P-RD Capsule interacts with the following medicines:

Strong CYP3A4 inhibitors: Medicines such as ketoconazole and clarithromycin can interact with P-RD Capsule, leading to increased levels in the blood and a higher risk of QT prolongation.
Proton pump inhibitors: Medications like omeprazole and esomeprazole can interact with P-RD Capsule, potentially reducing the effectiveness of this medicine.
Anticoagulants: Medicines like warfarin may interact with P-RD Capsule, potentially increasing INR. Regular monitoring is recommended.

Drug-Food Interactions

Certain foods may interact with P-RD Capsule:

Acidic Foods: Foods such as citrus fruits or tomatoes might reduce the effectiveness of pantoprazole in P-RD Capsule.

Drug-Disease Interactions

P-RD Capsule interacts with the following diseases:

Cardiac Arrhythmia: As Domperidone in P-RD Capsule can cause QT prolongation, those with cardiac arrhythmias should take this medicine only under medical supervision.
Electrolyte Imbalance: People suffering from electrolyte imbalance should use P-RD Capsule carefully as it may cause further disturbances.

Daily Dose

The dosage of P-RD Capsule should be as prescribed by your doctor. The amount you take could change based on factors like how severe your condition is and how you respond to the medication. It's essential to stick to the prescribed dosage and not exceed it without first consulting your doctor.

Over Dose

If you accidentally take more P-RD Capsules than suggested, you might feel drowsy, confused, and experience an unusual heartbeat. You may also have a headache, blurred vision, feel flushed, or nauseated. If these overdose symptoms persist, inform your doctor.

Missed Dose

If you forget to take your P-RD Capsule, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store P-RD Capsule in a dry place below 30°C.
Keep it away from direct sunlight and moisture.
Always keep this medication out of the reach of children.
Ensure to use it before the expiry date mentioned on the pack.

Limit intake of spicy or fatty foods, as they may aggravate symptoms of gastroesophageal reflux disease (GERD).
Refrain from consuming alcohol and smoking cigarettes, as they may worsen your condition and interfere with the effectiveness of P-RD Capsule.

Fact Box

Drug Category	Dopamine-2 Antagonist, Proton Pump Inhibitor
Therapeutic Category	Gastrointestinal Agent
Available Dosage Types	Capsule
Habit Forming	No
Ailment	GERD, Delayed Gastric Emptying, Nausea

What is P-RD Capsule?

P-RD Capsule is a medication combining Domperidone and Pantoprazole, used to manage gastroesophageal reflux disease (GERD) and delayed gastric emptying.

How does P-RD Capsule work?

Domperidone in P-RD Capsule improves stomach muscle movement, promoting faster food transit; Pantoprazole reduces stomach acid production, helping heal the digestive tract.

Can I crush or chew the P-RD Capsule?

No, you should swallow the P-RD Capsule whole without crushing or chewing to ensure its sustained-release formulation works as intended.

Who should avoid taking the P-RD Capsule?

Those allergic to Domperidone, Pantoprazole or any capsule ingredients, with severe liver disease or history of heart rhythm problems, should avoid taking P-RD Capsule.

What are the possible side effects of P-RD Capsule?

Common side effects include headache, dizziness, diarrhoea, abdominal pain, flatulence, nausea, and rash. Consult your doctor if these persist or worsen.

Can I take other medicines while using P-RD Capsule?

Some medicines may interact with P-RD Capsule affecting its effectiveness or causing side effects. Always consult your doctor before starting new medications.

Should I take the P-RD Capsule before or after meals?

For optimal effectiveness, you should take the P-RD Capsule at least 30 minutes before a meal.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Peninsula Corporate Park, Peninsula Chambers, G.K Marg, Lower Parel West, Lower Parel, Mumbai, Maharashtra 400013

Country of origin: INDIA

References

PAN-D. (n.d.). https://www.alkemlabs.com/pdf/adverse/PAN%20D.pdf
P-RD. (n.d.). Prescribing information for Pantoprazole gastro-resistant and Domperidone prolonged-release capsules IP. https://bluecrosslabs.com/wp-content/uploads/2023/02/P-RD%20Capsules.pdf
Pantoprazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00213
Domperidone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01184

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