Pirox 05 Gel 20 Gm

Pirox 0.5 % Gel 20 GM

Cipla Ltd.

TUBE of 30 GM
TUBE of 20 GM

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MRP ~~₹41.31~~

₹33.87

₹2.07/GM

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Composition

Piroxicam (0.5 %)

Pirox Gel is used to manage moderate to severe pain and inflammation associated with various musculoskeletal disorders. This medicine belongs to a group called NSAIDs, specifically the oxicam class.

This gel is also used for conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute injuries like sprains, strains, and tendinitis. By applying directly to the affected area, it provides localized relief.

You should apply this medicine as directed by your doctor. Be sure to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while using this medicine, notify your doctor immediately. Continue applying the gel for the duration prescribed by your doctor for optimal results.

Pirox Gel is used for managing the following conditions:

Pain and inflammation related to Osteoarthritis
Rheumatoid arthritis-associated discomfort and swelling
Ankylosing spondylitis, a type of arthritis affecting the spine
Pain and inflammation resulting from acute musculoskeletal injuries, such as sprains and strains
Tendinitis, characterised by the swelling of a tendon

Directions for Use of Pirox 0.5 % Gel 20 GM

To use Pirox Gel appropriately, follow these instructions:

Ensure the area where you want to apply the gel is clean and dry.
Apply a thin layer of the gel to the affected area.
Gently rub the gel into your skin until it is fully absorbed.
After applying, wash your hands thoroughly unless they are in the area being treated.
For any specific advice on how to use Pirox Gel, consult your doctor.

Pirox Gel is applied topically.

Pirox Gel could lead to the following side effects:

Skin irritation or redness at the application site
Itching or a burning sensation
Dry skin
Photosensitivity: This is an increased sensitivity to sunlight, which might cause sunburn more easily than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pirox Gel. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Skin irritation or redness: If you notice any irritation or redness at the application site, try applying the gel less frequently.
Photosensitivity: Try to avoid direct sunlight and use a high-factor sunscreen to protect your skin when outdoors.

Pirox Gel contains piroxicam (0.5 %), which works on the body as follows:

Blocks Prostaglandin Production: Piroxicam works by blocking the production of certain chemical messengers called prostaglandins. These messengers are responsible for causing pain, inflammation, and fever in the body.
Inhibits the Enzyme Cyclooxygenase: Piroxicam inhibits the enzyme cyclooxygenase (COX). This enzyme is involved in the synthesis of prostaglandins, the key mediators of pain and inflammation. By reducing prostaglandin production at the site of application, Piroxicam helps reduce pain, swelling, and stiffness in the affected joints or muscles.

Pregnancy

Caution is advised while using Pirox Gel if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

The safety of Pirox Gel during breastfeeding has not been established. Consult your doctor before using this product if you are breastfeeding.

Alcohol

Caution is advised when consuming alcohol while using this medicine.

Liver

Caution is advised while using Pirox Gel in case of mild to moderate liver impairment. If you have liver problems, discuss them with your doctor before starting Pirox Gel.

Kidney

If you have a history of any kidney problems, caution is advised before using Pirox Gel. Consult your doctor for guidance.

Using Machines & Driving

There's no known effect of Pirox Gel on the ability to drive or operate machinery. However, if you experience any side effects that could affect this ability, avoid these activities and consult your doctor.

Allergy

Pirox Gel is contraindicated in individuals with known hypersensitivity to Piroxicam or any other NSAID. Inform your doctor about any allergies before starting this medicine.

Children

Pirox Gel should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should use Pirox Gel under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pirox Gel interacts with the following medicines:

Other Topical NSAIDs: Using multiple topical NSAIDs (e.g., diclofenac) can increase the risk of skin irritation or side effects.
Corticosteroids: Topical corticosteroids used with piroxicam may increase the risk of skin thinning or irritation.
Anticoagulants: Though the risk is lower with topical use, caution is advised if using with blood thinners (e.g., warfarin) due to a potential increase in bleeding risk.

Drug-Food Interactions

There are no known specific food interactions with Pirox Gel.

Drug-Disease Interactions

Pirox Gel interacts with the following diseases:

Asthma: Individuals with asthma should exercise caution as Pirox Gel could exacerbate their condition.
Peptic Ulcers: Patients with active peptic ulcers or a history of recurrent ulceration should avoid using Pirox Gel due to the increased risk of gastrointestinal issues.
Cardiovascular Disease: People suffering from cardiovascular disease need to be cautious because Piroxicam, an ingredient in Pirox Gel, has been associated with an increased risk of heart attack and stroke.

Daily Dose

Apply Pirox Gel as directed by your doctor. Your dosage may differ based on individual factors like the severity of your condition and how you respond to the medicine. Always stick to your prescribed dosage and don't increase it without speaking to your doctor.

Over Dose

If you accidentally apply more Pirox Gel than recommended, you may experience symptoms such as skin irritation or redness at the application site. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to apply Pirox Gel at the scheduled time, do it as soon as you remember. However, if it's nearly time for your next application, skip the missed one and continue as usual. Avoid doubling up applications without consulting with your doctor.

Store Pirox Gel at room temperature, ideally below 30 degrees Celsius.
Ensure it's kept away from excessive heat and moisture.
Keep the tube tightly closed when not in use to prevent air exposure.
Always keep this medicine out of sight and reach of children.
Make sure to use Pirox Gel before the expiry date printed on the package.

If you're dealing with osteoarthritis or rheumatoid arthritis, consider eating more omega-3 fatty acids. Foods like fish, walnuts, and flaxseeds can help manage inflammation associated with these conditions.
Regular low-impact exercises such as swimming, walking, or cycling can improve joint mobility and reduce stiffness, making it easier for Pirox Gel to do its job. Please consult your doctor before beginning any new exercise regimen.

Fact Box

Drug Category	Cyclooxygenase Inhibitor
Therapeutic Category	NSAID
Available Dosage Types	Gel
Habit Forming	No
Ailment	Osteoarthritis, Rheumatoid arthritis, Musculoskeletal injuries

What is Pirox Gel used for?

Pirox Gel is used to manage pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and acute musculoskeletal injuries.

How does Pirox Gel work?

Pirox Gel contains piroxicam, which reduces the production of prostaglandins, chemicals that cause pain and inflammation, providing relief at the application site.

How do I Use Pirox Gel?

Apply a thin layer of Pirox Gel to the affected area as directed by your doctor. Always wash your hands after application.

Are there any sde effects with Pirox Gel?

Yes, you may experience skin irritation, redness, dry skin, or increased sensitivity to sunlight. Contact your doctor if these side effects persist or worsen.

Can I use Pirox Gel if pregnant or breastfeeding?

The safety of Pirox Gel during pregnancy and breastfeeding hasn't been established. Always consult your doctor before using if you're pregnant or nursing.

What should I do if I miss a dose of Pirox Gel?

If you miss a dose, apply as soon as you remember. If it's nearly time for the next dose, skip the missed one and continue with your schedule.

Can I use other medicines while using Pirox Gel?

Some medicines may interact with Pirox Gel. Inform your doctor about all medicines you are currently taking to avoid potential medicinal interactions.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Feldene* Piroxicam 0.5% Topical Gel. (n.d.). Retrieved November 18, 2024, from https://labeling.pfizer.com/ShowLabeling.aspx?id=18306
Feldene gel PIL CC 130122 Feldene Gel ® Piroxicam 0.5% (5 mg/g). (n.d.). Retrieved November 18, 2024, from https://mohpublic.z6.web.core.windows.net/IsraelDrugs/Rishum01_2_303468722.pdf
‌Piroxicam: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00554
Piroxicam: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a684045.html

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