Pioglit Mf 15500 Mg Tablet Er 10

Pioglit Mf 15 Tablet 10

Sun Pharma Laboratories Ltd.

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Composition

Metformin (500 Mg) + Pioglitazone (15 Mg)

Pioglit MF 15 Tablet is primarily used for managing type 2 diabetes mellitus in adults. This medicine is a combination of two active ingredients and belongs to the class of oral anti-diabetic medications.

Besides its main use, this medicine also aids in improving insulin sensitivity and regulating blood sugar levels in the body. It complements diet and exercise regimes to enhance glycemic control in individuals with type 2 diabetes.

You should take this medicine as directed by your doctor. Keep your doctor informed about any ongoing medications or pre-existing conditions before you start using this medicine. If you happen to notice any side effects, it's important to let your doctor know immediately. For the best results, continue taking the medicine for the duration prescribed by your doctor.

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Pioglit MF 15 Tablet is used for the following:

Managing type 2 diabetes in adults
Improving insulin sensitivity, helping your body use insulin more effectively
Regulating blood sugar levels when other therapies don't work adequately
Shifting from separate pioglitazone and metformin tablets to a combined therapy.

Directions for Use of Pioglit Mf 15 Tablet 10

Follow these instructions while taking Pioglit MF 15 Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing, splitting, or chewing the tablet.
It's essential not to stop taking this medicine without consulting your doctor first.
Remember, these are standard directions. Consult your doctor for specific advice.

Pioglit MF 15 Tablet is taken orally.

Pioglit MF 15 Tablet may have the following common side effects:

Upper respiratory tract infections
Headache
Diarrhoea
Nausea and vomiting
Flatulence: This medicine might cause excess gas in your stomach or intestines.
Abdominal discomfort
Weight gain
Oedema: This refers to swelling caused by excess fluid trapped in your body's tissues.
Bone fractures
Anaemia: This is a condition where you have fewer red blood cells than normal, which can make you feel tired.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pioglit MF 15 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Pioglit MF 15 Tablet with food to lessen this effect.
Flatulence: If you have excess gas, consider taking this medicine after meals to minimise this effect.

Pioglit MF 15 Tablet contains two active ingredients:

Pioglitazone (15 mg): As a thiazolidinedione, this ingredient works by stimulating a cell receptor called PPAR-γ. This receptor controls the function of genes that help manage glucose production and usage. By doing so, pioglitazone reduces insulin resistance in the liver and other tissues, which helps decrease blood sugar levels without causing low blood sugar, or hypoglycaemia.
Metformin (500 mg): This ingredient is a biguanide that acts by suppressing the production of glucose in the liver. It also reduces the absorption of glucose in the intestines and improves insulin sensitivity. This action enhances the uptake and use of glucose in the peripheral tissues. Similar to pioglitazone, metformin also aids in lowering blood sugar levels without causing hypoglycaemia. It does not lead to increased insulin levels either.

Pregnancy

Caution is advised while taking Pioglit MF 15 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

It's best to discuss with your doctor before using Pioglit MF 15 Tablet if you are breastfeeding.

Alcohol

Drinking alcohol while taking Pioglit MF 15 Tablet could increase the risk of lactic acidosis, a severe condition. It's advisable to limit your alcohol consumption when on this medication.

Liver

If you have liver health issues, it's crucial to consult your doctor before starting on Pioglit MF 15 Tablet, as this medicine could affect liver function.

Kidney

Patients with a history of kidney problems should exercise caution before using Pioglit MF 15 Tablet. Consulting your doctor prior is highly recommended.

Using Machines & Driving

Pioglit MF 15 Tablet doesn't affect your ability to drive or operate machinery. However, individual responses may vary and it's wise to see how you react to the medicine first.

Allergy

Pioglit MF 15 Tablet is contraindicated if you're allergic to pioglitazone, metformin, or any other ingredients in the tablet. If you have known allergies, discuss them with your doctor before starting this medicine.

Children

Pioglit MF 15 Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Pioglit MF 15 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pioglit MF 15 Tablet interacts with the following medicines:

Insulin or insulin secretagogues: When used in combination with these types of medicines, like glipizide or glyburide, Pioglit MF 15 Tablet can increase the risk of hypoglycaemia.
Cholesterol lowering medicines: Medicines like gemfibrozil can increase the exposure of pioglitazone in your body when taken with Pioglit MF 15 Tablet.
Carbonic anhydrase inhibitors: Medicines such as topiramate and zonisamide can increase the risk of lactic acidosis when used alongside Pioglit MF 15 Tablet.
Cationic medicines: These include medications like amiloride and digoxin, which can reduce the elimination of metformin when taken with Pioglit MF 15 Tablet.

Drug-Food Interactions

Drug-Disease Interactions

Pioglit MF 15 Tablet interacts with the following diseases:

Renal Impairment: If you have severe renal impairment, you should avoid taking this medicine as it can exacerbate your condition.
Heart Failure: Pioglitazone in Pioglit MF 15 Tablet can cause fluid retention, which may exacerbate or lead to heart failure.
Bladder Cancer: An increased risk of bladder cancer has been observed with pioglitazone use. Therefore, if you have active bladder cancer or a history of it, use this medicine with caution.

Daily Dose

The daily intake of Pioglit MF 15 Tablet should be as set by your doctor. It will depend on individual factors such as your health status and your reaction to the medication. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

In the event of an overdose, you might experience symptoms like abdominal pain, rapid breathing, irregular heartbeat, unusual muscle pain or extreme sleepiness. Seek medical attention if these symptoms persist.

Missed Dose

If you forget to take Pioglit MF 15 Tablet at the scheduled time, take it as soon as you recall. However, if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Never adjust your dosage without consulting your doctor.

Always store your Pioglit MF 15 Tablet in a tightly sealed container.
Keep it protected from light and moisture.
Store this medicine out of the reach of children.
Use the medicine before the expiry date printed on the pack.

Regular physical activity is recommended as it helps improve insulin sensitivity, which can aid in managing type 2 diabetes, the condition for which Pioglit MF 15 Tablet is prescribed.
Maintain a balanced diet that's low in sugars and refined carbohydrates. This can help regulate your blood sugar levels and enhance the effectiveness of Pioglit MF 15 Tablet.

Fact Box

Drug Category	Insulin Sensitizer, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Pioglit MF 15 Tablet?

Pioglit MF 15 Tablet is an oral medication for managing type 2 diabetes. It contains two active ingredients, pioglitazone (15 mg) and metformin (500 mg).

How does Pioglit MF 15 Tablet work?

The medicine reduces blood sugar levels by improving insulin sensitivity. pioglitazone reduces insulin resistance, while Metformin decreases glucose production and absorption.

When should I take Pioglit MF 15 Tablet?

You must take the medicine as directed by your doctor.

Who shouldn't take Pioglit MF 15 Tablet?

People with severe kidney problems, metabolic acidosis, active bladder cancer or congestive heart failure requiring treatment should avoid this medicine.

What are the side effects of Pioglit MF 15 Tablet?

Common side effects include upper respiratory tract infections, headaches, diarrhoea, nausea, flatulence, abdominal discomfort, and weight gain.

Can Pioglit MF 15 Tablet interact with other medications?

Yes, it can interact with several medicines. Always inform your doctor about any other medication you're currently taking before starting this medicine.

What should I do in case of an overdose?

If you suspect an overdose, seek immediate medical attention. Overdose can lead to lactic acidosis which requires urgent medical care.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

DailyMed - ACTOS- pioglitazone hydrochloride tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fd156adc-3174-44da-bff7-eeaef5983f18
Pioglitazone: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01132
PubChem. (n.d.). Pioglitazone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Pioglitazone
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
DailyMed - METFORMIN ER 500 MG tablet METFORMIN ER 750 MG tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html

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