Phoscut 400 Mg Tablet 10

Phoscut 400 Tablet 10

Steadfast Medishield Pvt Ltd

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Composition

Sevelamer (400 Mg)

Strength:

800 MG 400 MG

Phoscut 400 Tablet is primarily used to manage high levels of phosphorus in the blood, which is common in patients with end-stage renal disease (ESRD) undergoing haemodialysis. This medication is part of a group of medicines known as phosphate binders.

This medicine could indirectly help in reducing the risk of bone disorders and ectopic calcification, which are complications of ESRD. Keeping phosphorus levels under control also potentially contributes to decreasing parathyroid hormone levels, thus managing secondary hyperparathyroidism.

You should take this medicine as directed by your doctor. Make sure to inform your doctor about any ongoing medications or pre-existing conditions before starting on this medication. If you experience any side effects, notify your doctor immediately. It's essential to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Phoscut 400 Tablet is used for the following:

Managing increased serum phosphorus levels in people with end-stage renal disease who are undergoing hemodialysis.
Reducing the risk of ectopic calcification caused by elevated serum phosphorus.
Helping decrease parathyroid hormone (PTH) levels, which can lead to a bone disorder known as osteitis fibrosis in patients suffering from renal failure.
Lowering LDL cholesterol and total cholesterol levels is beneficial for overall heart health.

Directions for Use of Phoscut 400 Tablet 10

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet before consuming it as it could interfere with its effectiveness.
Never take more than your doctor has recommended. If you're unsure about your dosage, consult your doctor for clarity.

Phoscut 400 Tablet is taken orally.

Phoscut 400 Tablet may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Dyspepsia: This is a medical term for indigestion or discomfort in the upper abdomen.
Abdominal pain
Flatulence: This is a buildup of gas in your digestive system, commonly known as 'wind' or 'gas'.
Constipation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Phoscut 400 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage some common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Dyspepsia: If you experience indigestion after taking this medicine, consider taking it after meals.

Phoscut 400 Tablet contains sevelamer (400 mg), which works in your body as follows:

Phosphate Binding: Sevelamer can bind phosphates in the gastrointestinal tract. This binding process reduces the amount of phosphate absorbed into your body from your diet, effectively lowering your blood phosphorus levels.
Lipid Lowering: In addition to its primary phosphate-binding action, sevelamer has also been associated with decreases in total and LDL cholesterol levels. This can be advantageous for heart health in patients with ESRD.

Pregnancy

Caution is advised while taking Phoscut 400 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding women need to exercise caution while using Phoscut 400 Tablet. Please discuss with your doctor for an accurate understanding of the benefits and potential risks.

Alcohol

Moderation in alcohol consumption is always advisable while on any medication.

Liver

Phoscut 400 Tablet does not show significant interaction with the liver. But if you have liver issues, do discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Phoscut 400 Tablet if you have a history of kidney problems. It's wise to consult your doctor before taking this medicine.

Using Machines & Driving

No known effects of Phoscut 400 Tablet on the ability to drive or operate machinery have been reported.

Allergy

Phoscut 400 Tablet should not be taken if you have known hypersensitivity to sevelamer or any of its components. If you experience an allergic reaction, seek immediate medical help.

Children

Phoscut 400 Tablet's safety and efficacy in children are not established. Caution is advised while giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Phoscut 400 Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age and have kidney or liver issues or other medication, it is advisable to discuss these concerns with your doctor before starting treatment.

Drug-Drug Interactions

Phoscut 400 Tablet interacts with the following medicines:

Antibiotics: Some antibiotics like ciprofloxacin can have their effectiveness reduced when taken with Phoscut 400 Tablet. To avoid this, it's recommended to take these antibiotics at least 1 hour before or 3 hours after taking Phoscut 400 Tablet.
Heart medications: Certain heart medicines like digoxin can interact with Phoscut 400 Tablet. This interaction may lead to a decrease in the effectiveness of the heart medication.
Blood thinners: Warfarin, a blood thinner, could have its bioavailability reduced when taken alongside Phoscut 400 Tablet. Dosing should therefore be separated by at least an hour before or three hours after.
Blood pressure medications: Enalapril, a medication used to manage high blood pressure, may have its effectiveness reduced when taken with Phoscut 400 Tablet.
Beta-blockers: Metoprolol, a type of beta-blocker used for managing high blood pressure and heart conditions, may have reduced effectiveness if taken with Phoscut 400 Tablet.
Iron Supplements: Iron supplements can interact with Phoscut 400 Tablet and reduce their effectiveness.

Drug-Food Interactions

Phoscut 400 Tablet should be taken with meals for maximum effectiveness.

Drug-Disease Interactions

Phoscut 400 Tablet interacts with the following diseases:

Hypophosphatemia: Patients suffering from low phosphate levels in the blood (hypophosphatemia) should not take Phoscut 400 Tablet as it works by reducing phosphate levels further.
Bowel obstruction: In case of any bowel obstruction, Phoscut 400 Tablet is contraindicated as it can worsen the condition.

Daily Dose

The daily dose of Phoscut 400 Tablet should be taken as directed by your doctor. This may vary based on individual factors, such as the severity of your condition and how well you respond to the medicine. It's crucial to follow your doctor's prescribed dosage and not exceed it without their approval.

Over Dose

If you happen to take more than the prescribed dose of Phoscut 400 Tablet, you may experience common side effects like nausea, vomiting, or diarrhoea in a more severe form. If any symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you forget to take a dose of Phoscut 400 Tablet, take it as soon as you remember. However, if it's already close to the time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.

Keep Phoscut 400 Tablet in a cool, dry place, ideally at room temperature.
Make sure the tablet container is tightly closed to prevent exposure to air and moisture.
Store this medicine away from direct light.
Always keep this medicine out of the reach of children.
Use Phoscut 400 Tablet before the expiry date mentioned on the product packaging.

Since Phoscut 400 Tablet helps manage high phosphorus levels in your body due to kidney disease, it's important for you to follow a low-phosphorus diet. This means limiting foods like dairy products, nuts, seeds, beans and lentils.
Additionally, as you are likely on haemodialysis, ensure you maintain adequate fluid intake but avoid excessive liquids. Consulting your doctor for specific guidance tailored to your condition is recommended.

Fact Box

Drug Category	Phosphate Binder
Therapeutic Category	Hyperphosphatemia
Available Dosage Types	Tablet
Habit Forming	No
Ailment	End-stage Renal Disease, Hyperphosphatemia

What is Phoscut 400 Tablet used for?

Phoscut 400 Tablet is used to manage increased serum phosphorus levels in patients with end-stage renal disease who are on hemodialysis.

How does Phoscut 400 Tablet work?

This medicine contains sevelamer, a phosphate binder that reduces the absorption of phosphate from food, thereby controlling serum phosphate levels in the body.

Can I crush or chew Phoscut 400 Tablet before taking it?

No, you should swallow the tablet whole. Crushing or chewing it can cause its contents to expand and may affect how it works.

Are there any conditions in which I shouldn't take Phoscut 400 Tablet?

Yes, you should not take this medicine if you have hypophosphatemia (low phosphorus levels), bowel obstruction or if you're allergic to sevelamer or any other ingredients of the tablet.

What are some common side effects of Phoscut 400 Tablet?

Some common side effects include nausea, vomiting, diarrhoea, dyspepsia (indigestion), abdominal pain, flatulence (passing gas), and constipation.

Can I take other medicines with Phoscut 400 Tablet?

Some medicines may interact with sevelamer, affecting their absorption. You should ideally separate the dosing by at least 1 hour before or 3 hours after taking Phoscut 400 Tablet.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

106, Anupam Plaza-i, Lsc, Ghazipur, Ghazipur, Delhi, 110096

Country of origin: INDIA

References

Genzyme Corporation. (2000). Renvela prescribing information [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022127s011lbl.pdf
Renvela. (n.d.). Sevelamer Carbonate tablets and powder for oral suspension [Description]. https://www.sanofi.in/dam/jcr:c7b8bdab-5d5d-44ac-9617-1c8872d90fd3/Renvela%20Powder%20&%20Tabs%20PI%20rev%20Feb22.pdf
DailyMed - SEVELAMER HYDROCHLORIDE tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2cd6512f-0edd-4a30-a4fa-aa996038633c
Sevelamer: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00658
Sevelamer: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a601248.html

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