The following are the side effects of Paraxin 500 mg capsule:
- Nausea: Nausea is a typical side effect of Paraxin 500 mg capsule. It is a feeling of discomfort in the stomach that may be accompanied by an urge to vomit.
- Vomiting: Vomiting is a common side effect of Paraxin 500 mg capsule. It is forcefully expelling the stomach's contents through the mouth.
- Diarrhoea: Paraxin 500 mg capsule may cause diarrhoea, a common side effect. It is characterised by loose, watery stools that occur more frequently than usual.
- Abdominal pain: Abdominal pain is a common side effect of Paraxin 500 mg capsule. It is a pain or discomfort in the area between the chest and the pelvis.
- Headache: Headache is a frequent side effect of Paraxin 500 mg capsule. It is a pain or discomfort in the head that may accompany other symptoms such as nausea, vomiting, photophobia and increased sensitivity to sound.
- Dizziness: Dizziness is a typical side effect of Paraxin 500 mg capsule. It is a feeling of lightheadedness or unsteadiness that may accompany other symptoms, such as nausea and sweating.
Managing the Side Effects
Here are some common management strategies for different side effects:
Diarrhoea
- Probiotics are helpful bacteria that help restore the balance of beneficial bacteria in the stomach and treat antibiotic-induced diarrhoea.
- You can consume probiotic-rich foods like yoghurt or take probiotic supplements.
Nausea and Vomiting
- Follow simple meals. Avoid eating oily, fried or spicy foods. Take a Paraxin 500 mg capsule before or after the meal. Do not sleep right away after eating. Consult your doctor if the symptom persists.
Headache and dizziness
- Drink enough water and avoid skipping meals. Take adequate rest. Try to be relaxed and stress-free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom continues. If you are experiencing dizziness, avoid activities requiring mental alertness or physical coordination until these symptoms subside.
Abdominal pain
- A common side effect of Paraxin 500 mg capsule is abdominal pain that can be managed by taking the medication with food.
Precautions
Pregnancy
It is prohibited to use Paraxin 500 mg capsule during pregnancy. The potential undesirable effects of the Paraxin 500 mg capsule can harm both the mother's and the fetus's health. Before taking Paraxin 500 mg capsule, check with your doctor if you are pregnant or planning to become pregnant.
Breastfeeding
Paraxin 500 mg capsule is not recommended for breastfeeding women because the effects on breast milk and nursing infants are unknown. Before taking Paraxin 500 mg capsule, consult your doctor.
Alcohol
Alcohol does not appear to interact with Paraxin 500 Capsule. If you have any concerns, please see a doctor.
Liver
In patients with liver problems, Paraxin 500 Capsules should be used carefully. Individuals suffering from liver illness may have trouble absorbing drugs, increasing the likelihood of undesirable side effects. Before taking Paraxin 500 Capsule, consult your doctor.
Kidney
When taking the Paraxin 500 Capsule, patients with kidney disease or issues should proceed cautiously. Before taking a Paraxin 500 Capsule, seek medical advice from your doctor.
Using Machine and Driving
It is unclear whether Paraxin 500 Capsule will impair your ability to operate machines or drive.
Allergy
Patients with a history of allergy to Chloramphenicol should avoid using Paraxin 500 Capsules.
Use In Children
The usage of Paraxin 500 Capsule in children is not advised. If you have any concerns, please see a doctor.
Use In Older Patients
Patients who are elderly should use Paraxin 500 Capsule cautiously. Your doctor will decide the dosage, duration, and frequency of the Paraxin 500 Capsules based on the severity of your current illness and any other medical conditions you have.
Interaction
Drug-Drug Interactions
Here are some drug interactions you should be aware of when using Paraxin 500 Capsule:
- Antidepressants: Paraxin 500 Capsule may increase the blood levels of tricyclic antidepressants such as amitriptyline, nortriptyline, which can lead to toxic effects.
- Anti-epileptics: Paraxin 500 Capsule can decrease the effectiveness of anti-epileptic drugs, such as phenytoin or carbamazepine.
- Proton-pump inhibitors: Paraxin 500 Capsule can interfere with the absorption of proton-pump inhibitors like Pantoprazole and rabeprazole, reducing their effectiveness.
- Anticoagulants: Paraxin 500 Capsule can enhance the anticoagulant effect of warfarin, leading to an increased risk of bleeding.
- Immunosuppressants: Paraxin 500 Capsule can increase the blood levels of immunosuppressant drugs, such as cyclosporine or tacrolimus, which can lead to toxic effects.
- Chemotherapeutic drugs: Paraxin 500 Capsule can decrease the effectiveness of chemotherapeutic drugs, such as doxorubicin or cyclophosphamide.
- Benzodiazepines: Paraxin 500 Capsule can increase the blood levels of benzodiazepines, such as diazepam, which can lead to toxic effects.
- Azole antifungals: Paraxin 500 Capsule can increase the blood levels of azole antifungals, such as ketoconazole or fluconazole, which can lead to toxic effects.
- Macrolide antibiotics: Paraxin 500 Capsule can increase the blood levels of macrolide antibiotics, such as erythromycin, which can lead to toxic effects.
- Statins: Paraxin 500 Capsule can increase the blood levels of statins, such as simvastatin, which can lead to toxic effects.
- Anti-arrhythmic agents: Paraxin 500 Capsule can increase the blood levels of anti-arrhythmic agents, such as amiodarone, which can lead to toxic effects.
- Antivirals: Paraxin 500 Capsule can decrease the effectiveness of antiviral drugs, such as acyclovir or valacyclovir.
- Phosphodiesterase type 5 (PDE5) inhibitors: Paraxin 500 Capsule can increase the blood levels of PDE5 inhibitors, such as sildenafil or tadalafil, which can lead to toxic effects.
Drug-Food Interactions
It is essential to know interactions to ensure optimal effectiveness and safety of the medication. Here are the drug-food interactions of the Paraxin 500 mg capsule.
- Dairy products: Calcium in dairy products can bind to Paraxin 500 mg capsule in the gut and reduce its absorption. Therefore, avoiding consuming dairy products 2 hours before or after taking Paraxin 500 mg capsule is recommended.
- Iron-rich foods: Iron supplements or iron-rich foods such as red meat, spinach, and beans can bind to Paraxin 500 mg capsule and reduce its absorption. It is advised to separate the consumption of iron-rich foods or supplements by at least 2 hours from taking Paraxin 500 mg capsule.
- Alcohol: The combination of alcohol and Paraxin 500 mg capsule can cause additive effects on the central nervous system, leading to dizziness, confusion, and impaired coordination. Therefore, it is recommended to avoid alcohol consumption while taking Paraxin 500 mg capsule.
Drug-Disease Interactions
In the case of Paraxin 500 Capsule, several drug-disease interactions should be considered:
- Colitis: Paraxin 500 Capsule has been associated with developing pseudomembranous colitis, a severe colon inflammation. Patients with a history of colitis should be monitored closely while taking Paraxin 500 Capsule, and any signs of diarrhoea or abdominal pain should be reported to a healthcare provider immediately.
- Bone marrow suppression: Paraxin 500 Capsule can potentially suppress bone marrow function, decreasing red and white blood cell counts. Patients with pre-existing bone marrow suppression or blood disorders should be monitored closely while taking Paraxin 500 Capsule.
- Liver and kidney problems: Paraxin 500 Capsule is primarily metabolised by the liver and excreted by the kidneys. Patients with liver or kidney problems may have difficulty metabolising and excreting Paraxin 500 Capsule properly, leading to an increased risk of toxicity. Dose adjustments may be necessary for these patients.