Page 1 Mg Tablet 10

Page 1 MG Tablet 10

Orchid Chemicals & Pharmaceuticals Ltd

Pack of 10 Units

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MRP ~~₹44~~

₹36.08

₹4.40/Units

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Composition

Repaglinide (1 Mg)

Strength:

1 MG 0.5 MG

Page 1 mg Tablet is used primarily to manage type 2 diabetes mellitus. This medicine falls under the category of meglitinides or insulin secretagogues, which are a group of medicines that help regulate blood sugar levels.

Apart from this main use, this medicine is also beneficial in controlling post-meal blood glucose levels. It's particularly effective in managing blood sugar spikes that occur after meals, thus helping to maintain overall glucose balance.

Taking this medicine should always be under the guidance of your doctor, who will advise you on the correct dosage and frequency based on your individual needs. It's important to let your doctor know about any other diseases you might have or other medicines you are taking before starting on this medicine. If you experience any side effects while taking this medicine, immediately inform your doctor. For best results, continue taking the medicine for the entire duration prescribed by your doctor.

Page 1 mg Tablet is used for:

Management of type 2 diabetes mellitus
Lowering blood glucose levels in adults
Stimulation of insulin release, especially after meals
Regulation of postprandial glucose control

Directions for Use of Page 1 MG Tablet 10

Here are the instructions for taking Page 1 mg Tablet:

The tablet should be swallowed whole with a glass of water.
Do not crush or chew the tablet.
If you skip a meal, the corresponding dose of this medicine should also be skipped.
Remember to follow your doctor's advice regarding how to use this medicine properly.

Page 1 mg Tablet is taken orally.

Page 1 mg Tablet might have the following side effects:

Hypoglycaemia: This is a condition where your blood sugar level drops too low, causing symptoms such as shakiness, dizziness, sweating, hunger, irritability, and confusion.
Headache
Nausea
Diarrhoea
Constipation
Back pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Page 1 mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how you can manage some common side effects:

Hypoglycaemia: Ensure you eat regular meals while taking this medication to maintain your blood sugar levels.
Nausea: Try taking Page 1 mg Tablet with or after meals to reduce the likelihood of feeling sick.

Page 1 mg Tablet contains repaglinide (1 mg), and it works on your body in the following ways:

ATP-dependent Potassium Channels Closure: Repaglinide binds to and closes the ATP-dependent potassium channels on the membranes of your pancreas's beta cells. The closure of these channels changes the electrical charge across the cell membrane, initiating a series of events inside the cell.
Voltage-gated Calcium Channels Opening: The change in electrical charge opens voltage-gated calcium channels, leading to an influx of calcium into the cell. The increase in intracellular calcium stimulates the release of insulin from the cell.
Insulin Secretion: The final step in the process is the secretion of insulin. Repaglinide induces the exocytosis, or release, of granules containing insulin from the beta cells of your pancreas. This release is dependent on the level of glucose in your body, meaning more insulin is released when your glucose levels are higher.

Pregnancy

Caution is advised while taking Page 1 mg Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Page 1 mg Tablet should be avoided during breastfeeding. It is recommended to discuss this with your doctor for understanding the potential risks and benefits.

Alcohol

Caution is advised when consuming alcohol while on Page 1 mg Tablet. Alcohol could potentially amplify the risk of hypoglycaemia or low blood sugar levels. It's a good idea to discuss this with your doctor.

Liver

If you have liver problems, caution is advised while taking Page 1 mg Tablet. This medicine may affect liver function, so it's advisable to discuss any liver-related concerns with your doctor before starting treatment with this medicine.

Kidney

If you have a history of any kidney problems, caution is advised before using Page 1 mg Tablet. Consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are suggested for using machines or driving while on Page 1 mg Tablet. However, if you experience symptoms like dizziness or confusion (which might indicate hypoglycaemia), avoid such activities and consult your doctor promptly.

Allergy

Page 1 mg Tablet is contraindicated if you have known hypersensitivity to repaglinide or any inactive ingredients in the tablet. In case of any allergic reactions, seek immediate medical attention.

Children

Caution is advised while giving Page 1 mg Tablet to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Page 1 mg Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age who might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Page 1 mg Tablet interacts with the following medicines:

Cholesterol lowering agents: Medicines like gemfibrozil can substantially increase repaglinide levels in your body, leading to a higher risk of hypoglycaemia.
Antifungals: Medicines such as ketoconazole and itraconazole can increase the concentration of repaglinide in your system, enhancing its hypoglycaemic effects.
Antibiotics: Medicines like rifampin may reduce the effectiveness of repaglinide by speeding up its metabolism in your body.

Drug-Food Interactions

There are no specific known food interactions with Page 1 mg Tablet.

Drug-Disease Interactions

Page 1 mg Tablet interacts with the following diseases:

Liver Impairment: Patients with liver disease may need lower doses of this medicine as it's extensively metabolised in the liver.
Kidney Disease: Caution is advised for patients with kidney impairment as altered kidney function could affect repaglinide's elimination from your body.
Adrenal or Pituitary Insufficiency: These conditions can increase your risk of hypoglycaemia while taking Page 1 mg Tablet. Regular monitoring of blood glucose levels is essential.

Daily Dose

Your doctor will prescribe the daily dose of Page 1 mg Tablet for you. This may vary depending on factors like how severe your condition is and your response to the medication. Always adhere to the prescribed dosage and do not alter it without consulting your doctor. Consult the package insert for more details.

Over Dose

If you happen to take more than your prescribed dose of Page 1 mg Tablet, you might experience symptoms like dizziness, sweating, and confusion. These are signs of hypoglycaemia, a common side effect of overdose. If these symptoms persist, inform your doctor.

Missed Dose

Missed a dose of Page 1 mg Tablet? Don't worry. Take the missed dose as soon as you remember it. If it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Remember, never adjust your dosage without speaking to your doctor first.

Store your Page 1 mg Tablet at room temperature.
Keep it in a dry area, away from direct sunlight and moisture.
Ensure it's kept in a tightly closed container.
Always keep this medicine out of reach of children.
Remember to use the medicine before its expiry date.

Aim to incorporate regular physical activity into your daily routine. Exercise can help manage blood glucose levels, especially for individuals with type 2 diabetes.
Focus on having a balanced diet rich in fibre, but low in sugars. This can assist you in controlling your post-meal glucose levels, which Page 1 mg Tablet specifically targets.

Fact Box

Drug Category	Insulin Secretagogue
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is Page 1 mg Tablet used for?

Page 1 mg Tablet is used to manage type 2 diabetes in adults, in combination with a healthy diet and regular exercise.

How does Page 1 mg Tablet work?

It contains repaglinide which stimulates the pancreas to release more insulin, particularly after meals, thus helping manage blood glucose levels.

When should I take Page 1 mg Tablet?

This medicine is taken orally, right before your main meals. If you skip a meal, also skip the corresponding dose.

What are the common side effects of Page 1 mg Tablet?

Common side effects include hypoglycaemia (low blood sugar), headache, nausea, diarrhoea, constipation and back pain. Consult your doctor if these persist or worsen.

What precautions should I take while using Page 1 mg Tablet?

You should monitor your blood glucose levels regularly. Exercise caution if you have liver or kidney impairment or are pregnant. Always consult your doctor.

Can I take other medicines while Using Page 1 mg Tablet?

Certain medicines can interact with repaglinide. Inform your doctor about all medicines you're taking to avoid any potential interactions.

How should I store Page 1 mg Tablet?

Store it at room temperature. Keep it away from moisture and out of reach of children.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Orchid Pharma Ltd, 'Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India

Country of origin: INDIA

References

Novo Nordisk. (1997). PRANDIN. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020741s041s042lbl.pdf
REPAGLINIDE TABLETS, USP. (2012). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/077571s000lbl.pdf
Repaglinide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00912
Repaglinide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a600010.html

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