Oxtiv Ap 0125 Gel 15 Gm

Oxtiv-ap 0.1/2.5 % Gel 15 GM

Alkem Laboratories Ltd.

Pack of 15 GM

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MRP ~~₹285.08~~

₹233.77

₹19.01/GM

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Composition

Adapalene (0.1 %) + Benzoyl Peroxide (2.5 %)

Oxtiv-ap 0.1/2.5 % Gel 15 GM is predominantly used for the management of acne vulgaris. This combination medicine belongs to the class of topical retinoids and antibacterials.

Acne vulgaris, commonly known as acne, affects areas with a high density of sebaceous glands like the face, chest, and back. It involves both inflammatory lesions (papules, pustules, nodules) and non-inflammatory lesions (open and closed comedones). This condition is common among teenagers due to hormonal changes but can persist into adulthood.

You should apply this gel as directed by your doctor. Before you start using this medicine, it is important to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while using this gel, notify your doctor immediately. It's crucial to continue using the gel for the duration prescribed by your doctor for optimal results.

Oxtiv-ap 0.1/2.5 % Gel 15 GM is used for the following:

Managing acne vulgaris.
Reducing excess sebum production is a key contributor to acne development.
Decreasing abnormal keratinization and blockage of follicles, which lead to done formation.
Controlling the proliferation of propionibacterium acnes bacteria, implicated in the inflammation associated with acne.

Directions for Use of Oxtiv-ap 0.1/2.5 % Gel 15 GM

Here's how you should use Oxtiv-ap 0.1/2.5 % Gel 15 GM:

Ensure your skin is clean and dry before application.
Apply a thin layer of the gel on the affected areas.
Wash your hands both before and after applying the gel.
Avoid contact with your eyes, mouth, angles of your nose and mucous membranes.
Do not apply on cuts, abrasions or sunburned skin.
Minimise exposure to sunlight and use sunscreen. Consult your doctor for more specific advice.

Oxtiv-ap 0.1/2.5 % Gel 15 GM is applied topically.

Side Effects of Oxtiv-ap 0.1/2.5 % Gel 15 GM

Oxtiv-ap 0.1/2.5 % Gel 15 GM may have the following common side effects:

Skin irritation
Erythema: This is a technical term for redness of the skin.
Scaling: You might notice your skin peeling or flaking.
Dryness
Stinging or burning sensation
Photosensitivity

Managing the Side Effects:

The majority of side effects are temporary and generally harmless, which resolve once you stop using Oxtiv-ap 0.1/2.5 % Gel 15 GM. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Skin irritation: Applying a moisturiser on your skin before using Oxtiv-ap 0.1/2.5 % Gel 15 GM can help manage these effects.
Photosensitivity: Limiting your exposure to sunlight and wearing sunscreen can help manage this effect.

Oxtiv-ap 0.1/2.5 % Gel 15 GM contains two active ingredients:

Adapalene (0.1%): This third-generation topical retinoid binds to specific retinoic acid nuclear receptors in your skin cells and modulates their growth and maturation processes. By doing so, adapalene normalises the growth of skin cells within hair follicles, reducing the formation of acne-causing blockages called microcomedones.
Benzoyl peroxide (2.5%): As an oxidising agent with antibacterial and exfoliating effects, benzoyl peroxide releases free oxygen radicals which kill acne-causing bacteria in hair follicles by oxidising their proteins. Its exfoliating effect aids in the expulsion of comedones – blocked hair follicles that cause acne – thereby helping to clear your pores.

Pregnancy

If you are pregnant or planning to conceive, it's recommended to discuss this with your doctor before starting this medication.

Breastfeeding

For safety, consult your doctor if you are a breastfeeding mother and consider using this medicine.

Alcohol

It's advisable to consult your doctor about consuming alcohol while using this medication.

Liver

Liver health issues have limited influence on the use of Oxtiv-ap 0.1/2.5 % Gel 15 GM as it's a topical product. However, if you have any liver conditions, it's always better to talk with your doctor first.

Kidney

As Oxtiv-ap 0.1/2.5 % Gel 15 GM is applied topically, kidney health generally doesn't impact its use. Still, if you have any kidney-related conditions, consider discussing this with your doctor before using this medicine.

Using Machines & Driving

Oxtiv-ap 0.1/2.5 % Gel 15 GM is unlikely to affect your ability to drive or operate machinery. However, if you experience any discomfort or skin irritation that may distract you, avoid these activities until the symptoms subside.

Allergy

This medicine is contraindicated in patients allergic to adapalene, benzoyl peroxide or any other ingredient in the formulation. If you have known allergies, ensure your doctor is aware before starting this medication.

Children

Caution is advised while using Oxtiv-ap 0.1/2.5 % Gel 15 GM in children under 12 years as its efficacy and safety haven't been established in this age group. Always consult your doctor before applying this medicine to a child.

Older Patients

Older patients should use Oxtiv-ap 0.1/2.5 % Gel 15 GM under medical supervision as they might be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Oxtiv-ap 0.1/2.5 % Gel 15 GM

Drug-Drug Interactions

Oxtiv-ap 0.1/2.5 % Gel 15 GM interacts with the following medicines:

Drying agents: Certain drying agents like salicylic acid and alcohol-based products may intensify the drying effect of Oxtiv-ap 0.1/2.5 % Gel 15 GM, leading to excessive skin dryness.
Irritant products: Care should be taken when using other topical products that are irritant in nature such as resorcinol, sulphur, or tretinoin concurrently with Oxtiv-ap 0.1/2.5 % Gel 15 GM, as these could exacerbate skin irritation.

Drug-Food Interactions

There are no known food interactions with Oxtiv-ap 0.1/2.5 % Gel 15 GM. As it is a topical medication, its efficacy is not affected by your diet.

Drug-Disease Interactions

Oxtiv-ap 0.1/2.5 % Gel 15 GM interacts with the following diseases:

Eczema: If you have eczema, applying Oxtiv-ap 0.1/2.5 % Gel 15 GM could potentially worsen your condition due to its drying effect.
Sunburn: Using this medication on sunburned skin may intensify discomfort and irritation.
Hypersensitivity: If you are hypersensitive to adapalene or benzoyl peroxide, using Oxtiv-ap 0.1/2.5 % Gel 15 GM could trigger allergic reactions.

Daily Dose

The daily dose of Oxtiv-ap 0.1/2.5 % Gel 15 GM should be applied as directed by your doctor. This may vary based on factors such as the extent of your acne and how well you respond to the medication. Follow the advised dosage diligently and don't exceed it without consulting your doctor.

Over Dose

Overdosing on Oxtiv-ap 0.1/2.5 % Gel 15 GM could lead to increased skin irritation, redness, peeling, or a burning sensation. In case you apply too much, wash the area with lukewarm water. If any discomfort persists or worsens, inform your doctor.

Missed Dose

In case you forget to apply Oxtiv-ap 0.1/2.5 % Gel 15 GM as instructed, apply it as soon as you remember. However, if it's nearly time for your next application, skip the missed one and go back to your normal schedule. Never increase your dosage without consulting your doctor.

Store Oxtiv-ap 0.1/2.5 % Gel 15 GM in a dry place at room temperature, specifically below 25°C.
Do not freeze.
Avoid exposure to direct sunlight or high heat.
Keep the tube tightly closed when not in use to prevent contamination.
Always keep out of reach of children to ensure safety.

Since Oxtiv-ap 0.1/2.5 % Gel 15 GM is used to manage acne, consider reducing your intake of oily and sugary foods as they can potentially worsen acne conditions.
Incorporate a regular skincare routine that includes cleansing your face at least twice a day, which can help reduce excess oil and dirt, further preventing acne flare-ups.

Fact Box

Drug Category	Topical Retinoid, Oxidising Agent
Therapeutic Category	Anti-acne Gel
Available Dosage Types	Gel
Habit Forming	No
Ailment	Acne vulgaris

What is Oxtiv-ap 0.1/2.5 % Gel 15 GM used for?

Oxtiv-ap 0.1/2.5 % Gel 15 GM is primarily used to manage acne vulgaris, a common skin condition that involves oil glands at the base of hair follicles.

How does Oxtiv-ap 0.1/2.5 % Gel 15 GM work?

Oxtiv-ap 0.1/2.5 % Gel 15 GM contains adapalene and benzoyl peroxide which work together to reduce inflammation, kill acne-causing bacteria and help prevent pore blockage, thus managing acne.

When will I see results from using Oxtiv-ap 0.1/2.5 % Gel 15 GM?

Visible improvement typically occurs after 4-8 weeks of regular use. However, maximum effectiveness is usually seen after about 3 months of use.

Can I apply makeup after using Oxtiv-ap 0.1/2.5 % Gel 15 GM?

Yes, you can apply non-comedogenic, non-irritating makeup 30 minutes after applying the gel to allow it to dry completely.

Can I use a moisturiser along with Oxtiv-ap 0.1/2.5 % Gel 15 GM?

Yes, if your skin becomes overly dry or starts peeling, you can apply a non-comedogenic moisturiser following the application of the gel.

How long should I use Oxtiv-ap 0.1/2.5 % Gel 15 GM?

The duration of use depends on your acne severity and should be as directed by your doctor. Abrupt discontinuation may cause a flare-up in acne.

What should I do if I experience severe irritation with Oxtiv-ap 0.1/2.5 % Gel 15 GM?

If you experience severe irritation, immediately stop using the gel and consult your doctor for an alternative treatment or lower-strength preparation.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Adapalene Topical. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a604001.html
U.S. National Library of Medicine. (2022). DailyMed - Benzoyl Peroxide Gel. DailyMed. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=0ba5e88c-a4d5-4550-93fa-d3d7fee45f9f&type=display
U.S. Food and Drug Administration. (2022). Label: Adapalene Gel. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021753s011lbl.pdf
Adapalene: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00210
Benzoyl peroxide: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09096

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