N Lok 5 Mg Tablet 10

N Lok 5 MG Tablet 10

Medopharm

Pack of 10 Units

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MRP ~~₹30~~

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Composition

Cilnidipine (5 Mg)

Strength:

10 MG 5 MG

N Lok 5 MG Tablet 10 is used for managing hypertension, also known as high blood pressure. This medicine belongs to a group of medications known as calcium channel blockers, specifically the dihydropyridine subclass.

This tablet helps in reducing the risk of serious cardiovascular events such as heart attacks and strokes. It is also believed to improve vascular endothelial function, reduce proteinuria in hypertensive patients, and lower nocturnal blood pressure.

Before you start taking this medicine, it is crucial to consult your doctor about your dosage and frequency. Also, inform your doctor about any pre-existing conditions or ongoing medicines you are taking. If you notice any side effects while on this medication, notify your doctor immediately. For optimal results, it's essential to continue taking the medicine for the duration prescribed by your doctor.

N Lok 5 MG Tablet 10 is used for the following:

Management of essential hypertension: This medicine helps to control high blood pressure.
Reducing the risk of cardiovascular events: It plays a role in preventing serious heart conditions such as heart attacks and strokes.
Improving vascular endothelial function: It aids in the better functioning of the linings of your blood vessels.
Lowering nocturnal blood pressure: It aids in managing high blood pressure during the night.

Directions for Use of N Lok 5 MG Tablet 10

Here's how to take N Lok 5 MG Tablet 10:

Consume this tablet orally with a glass of water.
Ensure you do not chew, crush, or break the tablet.
Take it around the same time each day for maximum effect.
Do not alter your dosage or stop taking this medicine without consulting your doctor first.

N Lok 5 MG Tablet 10 is taken orally.

N Lok 5 MG Tablet 10 may have the following side effects:

Headache
Dizziness
Fatigue
Abdominal Pain
Constipation
Flushing
Palpitations
Peripheral Edoema: This can cause swelling in your legs or arms due to fluid buildup.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of N Lok 5 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Flushing: Try taking the medicine at night if it causes flushing during the day.
Constipation: If constipation occurs after taking this medicine, consider taking it with meals to lessen this effect.

N Lok 5 MG Tablet 10 contains cilnidipine (5 mg), which works on your body as follows:

Blocks L-Type and N-Type Calcium Channels: Cilnidipine effectively blocks your body's L-type and N-type calcium channels. L-type calcium channels are found in the heart and blood vessels. Blocking these channels enables cilnidipine to relax and widen your blood vessels, reducing peripheral vascular resistance and lowering blood pressure.
Suppresses Norepinephrine Release: The N-type calcium channels are found in the sympathetic nerve endings. Blocking these channels suppresses the release of norepinephrine, a hormone that can increase heart rate and blood pressure. This suppression provides an additional anti-hypertensive effect.

This dual action on both L-type and N-type calcium channels sets cilnidipine apart from other calcium channel blockers that only target L-type channels.

Pregnancy

N Lok 5 MG Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's vital that you discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding women should not use N Lok 5 MG Tablet 10. Consult your doctor to understand the potential risks and benefits.

Alcohol

Alcohol may increase the blood pressure-lowering effect of this medicine. So, caution is advised when consuming alcohol while taking N Lok 5 MG Tablet 10.

Liver

If you have liver problems, you should be cautious when taking N Lok 5 MG Tablet 10. This medicine may affect liver function. Discuss your liver health with your doctor before starting this medication.

Kidney

Caution is advised before using N Lok 5 MG Tablet 10 if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

N Lok 5 MG Tablet 10 may cause dizziness or lightheadedness, especially when starting treatment or increasing the dose. Avoid driving or operating heavy machinery until you know how this medicine affects you.

Allergy

If you are allergic to cilnidipine or other dihydropyridine calcium channel blockers, do not take N Lok 5 MG Tablet 10. Discussing any allergies with your doctor before starting this medication is best.

Children

N Lok 5 MG Tablet 10 is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take N Lok 5 MG Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

N Lok 5 MG Tablet 10 interacts with the following medicines:

CYP3A4 inhibitors: Medications like itraconazole, ritonavir, and clarithromycin can increase cilnidipine levels, enhancing its blood pressure-lowering effects.
CYP3A4 inducers: Medications such as rifampicin, phenytoin, and carbamazepine may decrease cilnidipine concentrations, potentially reducing its effectiveness.
Alpha-blockers: Co-administration with alpha-blockers like Doxazosin and Terazosin may further lower blood pressure.

Drug-Food Interactions

Grapefruit juice: It inhibits the CYP3A4 enzyme and may substantially elevate cilnidipine levels.

Drug-Disease Interactions

N Lok 5 MG Tablet 10 interacts with the following diseases:

Liver disease: Patients with liver disease should exercise caution as this medicine could worsen their condition.
Kidney disease: Caution is advised in patients with kidney disease due to potential excessive lowering of blood pressure.
Coronary artery disease: N Lok 5 MG Tablet 10 may worsen angina in patients with underlying coronary artery disease.

Daily Dose

You should take your daily dose of N Lok 5 MG Tablet 10 as prescribed by your doctor. The dosage may vary depending on personal factors, such as the severity of your condition and your response to the medicine. Always follow your doctor's instructions, and avoid exceeding the prescribed dosage without consulting them.

Over Dose

Taking more than the prescribed dosage of N Lok 5 MG Tablet 10 can lead to symptoms such as severe low blood pressure and a slow heart rate. If you suspect an overdose, inform your doctor, who will guide you on the necessary steps.

Missed Dose

If you forget to take a dose of N Lok 5 MG Tablet 10, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store N Lok 5 MG Tablet 10 in a cool, dry place, protected from light and moisture.
Ensure the tablets are out of reach of children.
Always check the expiry date and avoid using this medicine past its expiration date.

Limit your intake of salt as it can exacerbate hypertension, which N Lok 5 MG Tablet 10 is used to manage.
Regular physical exercise, like walking or cycling, can help control high blood pressure.

Fact Box

Drug Category	Calcium Channel Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Essential Hypertension

What is N Lok 5 MG Tablet 10 used to manage?

N Lok 5 MG Tablet 10 is used to manage high blood pressure or hypertension, helping to reduce the risk of heart attacks and strokes.

How does N Lok 5 MG Tablet 10 work?

N Lok 5 MG Tablet 10 contains cilnidipine, which relaxes and widens your blood vessels, lowering your blood pressure. It also reduces the release of a hormone that can raise blood pressure.

Can I take N Lok 5 MG Tablet 10 if I'm pregnant?

No, N Lok 5 MG Tablet 10 should not be taken during pregnancy as it might harm the foetus. If you are of childbearing age, use effective contraception while taking this medicine.

Can I take other medicines with N Lok 5 MG Tablet 10?

Some medicines, like itraconazole and doxazosin, may interact with N Lok 5 MG Tablet 10, affecting its action or increasing side effects. Always inform your doctor about all other medications you're currently taking.

What are some common side effects of N Lok 5 MG Tablet 10?

Common side effects include headache, dizziness, flushing, swelling in peripheral parts of the body, fatigue, and digestive issues like nausea and constipation.

What precautions should I take when using N Lok 5 MG Tablet 10?

You should avoid sudden discontinuation of this medicine as it may lead to rebound hypertension. Always consult your doctor for proper dose adjustments or if discontinuation is required.

How should I store my N Lok 5 MG Tablet 10?

Store your N Lok 5 MG Tablet 10s at room temperature, away from light and moisture. Remember to keep them out of reach of children and pets.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Medo House, 25, Puliyur 2nd Main Rd, Ganga Nagar, Trustpuram, Kodambakkam, Chennai, Tamil Nadu 600024

Country of origin: INDIA

References

Godfraind, T. (2005). Calcium antagonists. Drugs, 65(16), 2193–2206
https://pubmed.ncbi.nlm.nih.gov/28611661/
Matsubara, Y., Nakamura, Y., Okada, T., Matsushima, S., Ohguchi, K., & Nishimura, M. (2002). Effect of Cilnidipine on peripheral and central blood pressure in essential hypertensives. Hypertension Research, 25(2), 177–183. https://pubmed.ncbi.nlm.nih.gov/11136301/
Kuriyama, S., Saito, Y., Nishimura, M., & Ohguchi, K. (2004). Effect of Cilnidipine on nocturnal blood pressure in patients with hypertension. Hypertension Research, 27(5), 375–380. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560139/
NCBI. (2021). Cilnidipine: A review on pharmacological and clinical aspects. Retrieved April 1, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695827/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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