Mycofit 500 Mg Tablet 10

Mycofit 500 Tablet 10

Intas Pharmaceuticals Ltd

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MRP ~~₹775.71~~

₹636.08

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Composition

Mycophenolate Mofetil (500 Mg)

Mycofit 500 Tablet is primarily used to prevent the body from rejecting a new organ after a kidney, heart or liver transplant. This medicine is part of a group known as immunosuppressants.

In addition to preventing organ rejection, this medicine is also used in managing severe active and persistent lupus nephritis, severe active rheumatoid arthritis, and refractory cases of Crohn's disease. By using this medicine in combination with other immunosuppressants like cyclosporine and corticosteroids, it aids in controlling these conditions.

Before starting this medicine, you should always consult with your doctor for proper dosage instructions. It's important to keep your doctor informed about any pre-existing conditions or ongoing medications before you begin taking this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Mycofit 500 Tablet is used for the following:

Preventing organ rejection following kidney transplant
Staving off organ rejection after heart transplant
Preventing organ rejection after liver transplant
Managing severe active and persistent lupus nephritis
Controlling severe active rheumatoid arthritis
Addressing refractory cases of Crohn's disease.

Directions for Use of Mycofit 500 Tablet 10

Follow these instructions while taking Mycofit 500 Tablet:

Swallow the tablet whole with a glass of water.
Refrain from crushing, chewing, or opening the tablet.
Do not exceed the recommended dose without consulting your doctor.
It's crucial not to discontinue this medication without consulting your doctor first.

Mycofit 500 Tablet is taken orally.

Mycofit 500 Tablet may have the following common side effects:

Diarrhoea
Nausea
Headache
Hypertension: This means high blood pressure, which can cause chest pain or shortness of breath.
Liver function test abnormalities: This could indicate potential liver damage or disease.
Hyperglycaemia: This is a condition where there is an excessive amount of glucose in your blood, commonly known as high blood sugar.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Mycofit 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Mycofit 500 Tablet with light food.
Nausea: Taking this medicine after meals might lessen this effect.

Mycofit 500 Tablet contains mycophenolate mofetil (500 mg). Here's a quick look at how it works:

Prodrug Conversion: Mycophenolate mofetil is a prodrug, which means it transforms into its active form, known as mycophenolic acid (MPA), in your body.
Inhibition of IMPDH: MPA prevents an enzyme called inosine monophosphate dehydrogenase (IMPDH) from functioning normally. This enzyme is vital for creating certain types of cells.
Suppression of Lymphocytes: IMPDH is particularly important for the development of T and B lymphocytes, which are types of white blood cells. Therefore, MPA has a stronger inhibitory effect on lymphocytes than on other cells.
Prevention of Organ Rejection: By suppressing lymphocyte proliferation, Mycofit 500 Tablet helps keep your body's immune system from attacking and rejecting the transplanted organ.

Pregnancy

Mycofit 500 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Mycofit 500 Tablet is contraindicated for breastfeeding women. It's crucial to consult your doctor to understand the potential risks and benefits.

Alcohol

It's always wise to be cautious and consult your doctor about drinking alcohol while taking this medication.

Liver

This medicine can be taken by people with liver issues, however, caution is advised. Discuss your liver health with your doctor before starting Mycofit 500 Tablet.

Kidney

In case of kidney impairment, dose adjustments might be necessary when using Mycofit 500 Tablet. Always share your kidney health history with your doctor before starting this medication.

Using Machines & Driving

There is no specific impact of Mycofit 500 Tablet on the ability to drive or operate machinery. As a precaution, ensure you know how this medicine affects you before driving or operating any machinery.

Allergy

If you have a known allergy to mycophenolate mofetil or any other components in Mycofit 500 Tablet, avoid taking this medication. If unsure about potential allergies, discuss them with your doctor.

Children

Caution is advised while giving Mycofit 500 Tablet to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Mycofit 500 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above the age of 70 years. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Mycofit 500 Tablet interacts with the following medicines:

Antacids and Proton Pump Inhibitors: Medicines like omeprazole or pantoprazole can reduce the absorption of mycophenolate mofetil, leading to lower levels in your body.
Immunosuppressants: Using Mycofit 500 Tablet alongside medications like azathioprine can increase the risk of bone marrow suppression, affecting your blood cell count.
Antibioics: Antibiotics like rifampin may reduce the effectiveness of Mycofit 500 Tablet by increasing its metabolism and elimination from your body.

Drug-Food Interactions

Consuming a high-fat meal before taking Mycofit 500 Tablet may reduce its absorption, leading to lower levels in your body.

Drug-Disease Interactions

Mycofit 500 Tablet interacts with the following diseases:

Renal impairment: If you have kidney problems, you might need dose adjustment for Mycofit 500 Tablet as it is excreted via the kidneys.
Hepatic impairment: Although dose adjustment is not necessary for those with liver issues, monitoring mycophenolate mofetil levels might be required.
Severe combined immunodeficiency (SCID): Patients with SCID have a risk of developing a rare brain infection called progressive multifocal leukoencephalopathy (PML) when they take Mycofit 500 Tablet.

Daily Dose

The daily dose of Mycofit 500 Tablet should be taken as recommended by your doctor. The dosage may vary depending on individual factors such as the severity of your condition and how you respond to the medicine. It's crucial to follow the prescribed dosage and not to increase it without consulting your doctor.

Over Dose

If you happen to take more than the prescribed dose of Mycofit 500 Tablet, you might experience symptoms like nausea, vomiting, and abdominal pain. If you suspect an overdose and these symptoms persist, inform your doctor about it.

Missed Dose

In case you forget to take a dose of Mycofit 500 Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Do not increase your dosage without consulting your doctor.

Store Mycofit 500 Tablet in a cool, dry place, protected from light.
The ideal storage temperature is below 30°C.
Make sure the product is kept out of reach of children.
Use the medicine before its expiry date.

If you're taking Mycofit 500 Tablet after an organ transplant, ensure you maintain a clean and hygienic diet. This will help avoid infections, as your immunity may be lowered.
Regularly monitor your blood sugar levels because this medication can sometimes lead to high blood sugar. If needed, adjust your diet to manage this. Always consult your doctor for specific advice.

Fact Box

Drug Category	Immunosuppressant
Therapeutic Category	Anti-rejection Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Organ rejection, Lupus nephritis, Rheumatoid arthritis

What is Mycofit 500 Tablet used for?

Mycofit 500 Tablet is used to prevent organ rejection in patients who have had kidney, heart, or liver transplants.

How does Mycofit 500 Tablet work?

This medicine works by inhibiting a key enzyme in immune cell proliferation, thereby preventing the body's immune system from rejecting the transplanted organ.

How should I take Mycofit 500 Tablet?

The tablet is taken orally. It should be swallowed whole and not crushed, chewed or opened.

Can pregnant or breastfeeding women take Mycofit 500 Tablet?

Due to potential harm to the fetus, pregnant women should avoid this medicine. Breastfeeding women should also refrain from using it as it may pass into breast milk.

Are there any side effects of taking Mycofit 500 Tablet?

Yes, possible side effects include diarrhoea, nausea, vomiting, abdominal pain, headache, hypertension, cough, liver function test abnormalities and increased blood sugar levels.

Can I take other medications along with Mycofit 500 Tablet?

Some medications may interact with Mycofit 500 Tablet, affecting its effectiveness. Always consult your doctor before starting any new medication.

What should I do in case of an overdose of Mycofit 500 Tablet?

In case of an overdose, seek immediate medical attention. Overdose may result in severe gastrointestinal and blood-related toxicity.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

Roxane Laboratories, Inc. (2001). Mycophenolate mofetil. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/065410s000lbl.pdf
Rx only. (n.d.). CellCept. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050722s021,050723s019,050758s019,050759s024lbl.pdf
DailyMed - MYCOPHENOLATE MOFETIL capsule MYCOPHENOLATE MOFETIL tablet. (n.d.). https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741e079a-646b-47ec-84ac-8e12574c2aaf&audience=consumer
Mycophenolate mofetil: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00688

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