Met Xl 125 Mg Tablet Er 20

Met Xl 12.5 Tablet 20

Ajanta Pharma Ltd

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Composition

Metoprolol Succinate (12.5 Mg)

Strength:

25 MG 50 MG 12.5 MG 100 MG

Met XL 12.5 Tablet is a beta-blocker used to manage high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythms (arrhythmia). It helps reduce the risk of heart attacks and strokes and is also used to treat heart failure. Additionally, Met XL 12.5 may be recommended for preventing migraines and relieving symptoms of an overactive thyroid (hyperthyroidism).

Remember to consult your doctor before starting Met XL 12.5 Tablet and follow their instructions carefully. They will determine the appropriate dosage based on your condition and response to treatment. It's also essential to be aware of any precautions or interactions associated with this medicine.

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Met XL 12.5 Tablet is used for managing the following health conditions:

Hypertension: Met XL 12.5 Tablet helps to lower high blood pressure by relaxing the blood vessels and reducing the workload on the heart. Controlling blood pressure reduces the risk of complications such as heart attacks, strokes, and kidney problems.
Angina: Angina occurs when the heart muscle doesn't receive enough oxygen-rich blood. Met XL 12.5 Tablet improves blood flow to the heart by dilating the blood vessels, relieving chest pain and discomfort associated with angina.
Arrhythmia: Arrhythmia refers to irregular heart rhythms. Met XL 12.5 Tablet helps stabilise the heart's rhythm by blocking specific receptors in the heart, which can help maintain a regular and steady heartbeat.
Diabetic Nephropathy: Kidney damage caused by diabetes can result in reduced kidney function.
Chronic Kidney Disease: Long-term damage to the kidneys, impairing their ability to filter waste from the blood.
Cardiovascular Protection: Met XL 12.5 Tablet helps protect against heart-related complications in individuals with existing heart conditions.
Migraine Relief: Met XL 12.5 Tablet has been found effective in preventing and reducing the frequency of migraines.

Directions for Use of Met Xl 12.5 Tablet 20

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Take the medicine in the dosage and frequency prescribed by your doctor.
It is crucial not to stop taking this medicine without consulting your doctor.

Met XL 12.5 Tablet is taken orally.

Below are a few common side effects of Met XL 12.5 Tablet you may experience:

Decreased blood pressure: Your blood pressure levels may drop below normal.
Dizziness: You may feel lightheaded or dizzy, especially when getting up from a sitting or lying position.
Fatigue: You may feel tired or have a lack of energy.
Nausea: You may feel the urge to vomit or experience an unsettled stomach.
Headache: You may experience a mild to moderate headache.
Stomach pain: Met XL 12.5 Tablet may cause stomach pain in some individuals.
Diarrhoea: This medication can sometimes lead to diarrhoea.

Consult your doctor if the side effects persist or become severe. This medication may also cause other side effects. Contact your doctor immediately if you notice anything unusual while using this medication.

Managing the Side Effects:

Here are some natural ways to manage the side effects of Met XL 12.5 Tablet:

Decreased blood pressure: Rise slowly when getting up from a seated or lying position.
Dizziness: Rise slowly from a sitting or lying position to avoid sudden changes in blood pressure.
Fatigue: Get plenty of rest and ensure a balanced diet to maintain energy levels.
Nausea: Eat smaller, more frequent meals and avoid spicy or greasy foods.
Headache: Apply a cold compress to your forehead or try relaxation techniques like deep breathing exercises.
Stomach pain: If you experience stomach pain, taking the medication with food or after a meal is advisable. Avoid consuming heavy or greasy meals that may worsen the pain.
Diarrhoea: Drink plenty of fluids to replace lost fluids. Avoid foods that can worsen diarrhoea, such as spicy or greasy foods, caffeine, and alcohol.

Met XL 12.5 Tablet contains metoprolol succinate (12.5 mg) as the active ingredient, which works in the human body in the following manner:

Metoprolol succinate works by blocking the action of epinephrine, a chemical substance that acts on your heart and blood vessels.
By inhibiting epinephrine, metoprolol succinate slows down your heartbeat and reduces the force with which your heart contracts.
As a result of slower and less forceful heartbeats, there is a decrease in your blood pressure.

Pregnancy

Is it safe to use the Met XL 12.5 Tablet during pregnancy?

Caution is advised while taking the medicine if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Is it safe to consume Met XL 12.5 Tablet during breastfeeding?

The medicine should be used with caution if you are breastfeeding. Discuss the potential risks and benefits with your doctor.

Alcohol

Is it safe to drink alcohol while taking Met XL 12.5 Tablet?

Avoid alcohol consumption while taking this medicine, as it may increase the possibility of side effects like dizziness and drowsiness. Always consult your doctor regarding alcohol intake.

Liver

Is it advisable to take Met XL 12.5 Tablet when experiencing liver problems?

This medicine may require careful monitoring of liver function. If you have liver problems, exercise caution and discuss your liver health with your doctor before starting the tablet.

Kidney

Is it advisable to consume Met XL 12.5 Tablet when experiencing kidney problems?

Exercise caution before taking the medicine if you have a history of kidney problems. It is best to consult your doctor before taking this medicine.

Using Machines & Driving

Is it safe to operate heavy machinery or drive when using the Met XL 12.5 Tablet?

Met XL 12.5 Tablet may cause dizziness or fatigue in some individuals, which could affect your ability to drive or operate machinery. Avoid such activities until you know how the medicine affects you.

Allergy

Are there any specific conditions that should be considered before taking the Met XL 12.5 Tablet?

The medicine is contraindicated in patients with known allergies to metoprolol succinate or any other tablet ingredients. Always discuss your allergies with your doctor.

Children

Is Met XL 12.5 Tablet suitable for infants or children?

The medicine should be given to children only under strict medical supervision. Always consult your child's doctor before giving any medicine to a child.

Older Patients

Is Met XL 12.5 Tablet suitable for older patients?

Older patients should take the medicine under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age, particularly if they have liver or kidney issues or are on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Met XL 12.5 Tablet may interact with the following medications:

Other antihypertensives: If you're taking medicines like atenolol, amlodipine, or diltiazem, Met XL 12.5 Tablet can potentially increase their effects, causing an overly slow heart rate (bradycardia) and low blood pressure.
CYP2D6 inhibitors: Medicines like fluoxetine and paroxetine, when taken along with the medicine, may increase the level of metoprolol succinate in your body, leading to sudden lowering of blood pressure (hypotension).
Antiarrhythmics: When used alongside medicines like amiodarone or flecainide, the tablet might alter their effectiveness in managing irregular heart rhythms.

Drug-Food Interactions

Certain foods can affect the absorption of Met XL 12.5 Tablet, such as:

High-fat meals: Consuming high-fat meals like dairy products, whole eggs, and fatty fish can slow down the absorption of metoprolol succinate, potentially decreasing its efficacy.
High-sodium food: Foods rich in sodium, like processed cheese and seafood, may reduce the effectiveness of the medicine.

Drug-Disease Interactions

Met XL 12.5 Tablet may interact with the following diseases:

Severe bradycardia: This medicine is contraindicated in patients with a significantly slow heart rate, as it could further slow your heartbeat.
Decompensated heart failure: People with decompensated heart failure, a critical stage of the disease where symptoms are at their worst, are contraindicated from taking this tablet as it could worsen their condition.
Bronchospastic disease: Met XL 12.5 Tablet is contraindicated in patients with such conditions.
Liver disease: If you have liver disease, the medicine might be metabolised slower in your body, potentially increasing its effects and side effects.

Daily Dose

The daily dose of Met XL 12.5 Tablet should be taken as directed by your doctor. The dosage may vary depending on factors like the severity of your condition and your body's response to the medicine.

Over Dose

If you accidentally take more than the prescribed dose of the medicine, you may experience symptoms like fatigue, a slow heart rate, dizziness, or nausea. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your regular dose of the medicine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store your Met XL 12.5 Tablet in a cool and dry place, ideally at room temperature below 30 degrees Celsius.
Keep it away from direct light and moisture to maintain its effectiveness.
Securely store this medicine out of the reach of children, ensuring their safety.
Always check the expiry date before taking the tablet; expired medicine may not be as effective.

To effectively manage high blood pressure, try to limit your salt intake. High salt intake can increase your blood pressure, opposing the effects of the medicine.
Regular moderate physical activity can support heart health. However, always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	Beta-Blocker
Therapeutic Category	Cardiovascular Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, angina, arrhythmia

What conditions does Met XL 12.5 Tablet manage?

Met XL 12.5 Tablet manages hypertension, angina, and irregular heart rhythms and also prevents heart attacks or strokes.

How does Met XL 12.5 Tablet work to manage these conditions?

The medicine reduces the heart's workload by slowing down the heart rate and reducing the force of each heartbeat.

How should I take Met XL 12.5 Tablet?

You should take this tablet at the same time each day, with or without food, as instructed by your doctor. Always follow your doctor's instructions regarding the dosage and frequency.

What are the possible side effects of Met XL 12.5 Tablet?

The common side effects of the medicine include fatigue, headache, slow heart rate, dizziness, nausea, and shortness of breath. If these symptoms persist or worsen, consult your doctor immediately.

Can I stop taking Met XL 12.5 Tablet abruptly?

No. Stopping suddenly can cause a rebound increase in blood pressure and heart rate, which could lead to a heart attack or stroke. Always consult your doctor before making any dose adjustments.

What is Met XL 12.5 Tablet used for?

Met XL 12.5 Tablet is used to manage high blood pressure (hypertension), angina (chest pain related to the heart), and irregular heart rhythms (arrhythmia).

Can I drink alcohol while taking Met XL 12.5 Tablet?

Drinking alcohol while on this medication may increase side effects like dizziness and drowsiness; it's, therefore, best to avoid alcohol consumption.

Last Updated On 15 Nov. 2024 | 8:21AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

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Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

References

Sun Pharmaceutical Industries, Inc. (2018b). Metoprolol succinate Extended-Release capsules prescribing information [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210428s000lbl.pdf
METOPROLOL SUCCINATE extended-release tablets. (2008). [Pharmaceutical]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019962s036lbl.pdf
Morris, J., Awosika, A. O., & Dunham, A. (2023b, August 29). Metoprolol. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK532923/
Gruetter Carl, A. (2007). Metoprolol. xPharm: The Comprehensive Pharmacology Reference. https://www.sciencedirect.com/science/article/abs/pii/B9780080552323621749
Metoprolol: MedlinePlus drug information. (2023, September 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682864.html

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