Magnex 1 Gm 500500 Mg Injection 1 Gm

Magnex 1g Injection 1

Pfizer Ltd

Vial of 1 UNITS

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MRP ~~₹626.79~~

₹513.97

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Composition

Cefoperazone (500 Mg) + Sulbactam (500 Mg)

Magnex 1g Injection is typically used for managing a wide range of bacterial infections. This medication is a combination medicine and belongs to the class of antibiotics.

Besides its primary purpose, this injection is also effective in managing infections in various parts of the body such as the ears, sinuses, throat, lungs, urinary tract, skin, and soft tissues. By combating these infections, the medicine aids in alleviating associated symptoms and promoting recovery.

It's vital to administer this medicine precisely as directed by your doctor. Prior to starting this medication, ensure your doctor is informed about any pre-existing health conditions or ongoing medications you are on. Should you experience any side effects during the course of this medication, notify your doctor straight away. It's crucial to complete the full course of this medication as prescribed by your doctor for it to be fully effective, even if symptoms improve sooner.

Magnex 1g Injection is commonly used for:

Managing bacterial infections in the ears
Controlling bacteria-induced sinus infections
Handling throat infections caused by bacteria
Coping with lung infections that are bacterial in nature
Tackling urinary tract infections due to bacteria
Dealing with skin and soft tissue bacterial infections

Directions for Use of Magnex 1g Injection 1

Administer Magnex 1g Injection as follows:

Magnex 1g Injection is administered by a healthcare professional.
The injection should be infused gradually.
It is crucial to complete the full course of this medicine, even if you start feeling better before it ends.
Do not abruptly discontinue the medicine without consulting your doctor first.

Magnex 1g Injection is administered intravenously.

Magnex 1g Injection may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Pain at the injection site
Thrombophlebitis: This is inflammation of a vein caused by a blood clot, which can occur at the injection site.
Pruritus: This is a sensation that makes you want to scratch your skin.
Urticaria: Also known as hives, it's marked by itchy red welts on the skin.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Magnex 1g Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try to have small frequent meals instead of three large ones.
Pain at the injection site: Applying a cold pack to the area can help reduce discomfort.

Magnex 1g Injection contains two active ingredients:

Sulbactam (500 mg): This component acts as a beta-lactamase inhibitor. It works by reducing the resistance of bacteria and thus boosts the effectiveness of the other components in this medicine.
Cefoperazone (500 mg): Classified as a third-generation cephalosporin antibiotic, cefoperazone functions by inhibiting bacterial cell wall synthesis. By doing so, it disrupts the growth and multiplication of bacteria within your body.

Pregnancy

If you're pregnant, caution is advised while considering Magnex 1g Injection. It's recommended to consult your doctor before starting this medication.

Breastfeeding

The safety of Magnex 1g Injection during breastfeeding isn't established. Therefore, it's best to talk to your doctor before taking this medicine if you're nursing.

Alcohol

Avoid drinking alcohol while on Magnex 1g Injection as it may lead to side effects. Consult your doctor for more information.

Liver

If you have liver problems, be cautious when using Magnex 1g Injection. The medicine's impact on liver function makes it necessary to discuss your liver health with your doctor before starting this medication.

Kidney

Caution is advised while administering Magnex 1g Injection if you have kidney health issues. Always consult your doctor before starting this medication.

Using Machines & Driving

Magnex 1g Injection may cause dizziness or sleepiness. Avoid driving or operating machinery until you know how the medicine affects you.

Allergy

Magnex 1g Injection is contraindicated if you're allergic to cefoperazone, sulbactam, or other beta-lactam antibiotics. Discuss your allergies with your doctor prior to using this medicine.

Children

Magnex 1g Injection should be given to children under adult supervision. Always consult a doctor before giving this medicine to a child.

Older Patients

Older patients should use Magnex 1g Injection under medical supervision due to potential increased susceptibility to side effects. Make sure to discuss any health concerns with your doctor before starting this medication.

Drug-Drug Interactions

Magnex 1g Injection interacts with the following medicines:

Aminoglycosides: When used alongside Magnex 1g Injection, medicines like gentamicin or amikacin may increase the risk of kidney damage.
Potent Diuretics: Diuretics, such as furosemide and torsemide, when taken with this medicine may lead to kidney problems.
Oral Anticoagulants: Magnex 1g Injection can increase the effects of anticoagulants like warfarin, leading to excessive thinning of blood.

Drug-Food Interactions

There are no specific food items known to interact with Magnex 1g Injection. However, it's always a good idea to follow a balanced diet while on medication.

Drug-Disease Interactions

Magnex 1g Injection interacts with the following diseases:

Renal Impairment: If you have kidney issues, this medication might cause complications since both cefoperazone and sulbactam are excreted through urine.
Colitis: Patients suffering from colitis need to be cautious as this medicine could exacerbate the condition.
Vitamin K Deficiency: This medication should be administered carefully in patients with Vitamin K deficiency as it could lead to complications.

Daily Dose

The daily dose of Magnex 1g Injection should be administered as prescribed by your doctor. The dosage may vary based on factors such as the severity of your condition and your response to the treatment. Always adhere to the prescribed dosage and refrain from exceeding it without consulting your doctor. For more specific information, refer to the package insert.

Over Dose

If there's an accidental overdose of Magnex 1g Injection, you might experience symptoms like nausea, vomiting, and diarrhoea. It's crucial to inform your doctor if these symptoms persist or worsen.

Missed Dose

In case you forget to administer this medicine as instructed, do it as soon as you remember. But, if it's almost time for your next dose, skip the missed one now and continue with your regular dosage schedule. Never increase the dosage without consulting your doctor.

Keep Magnex 1g Injection below 25°C.
Protect it from light.
Ensure the area is dry, as moisture can damage the medicine.
Always keep the medicine out of the reach of children.

Hydrate well: Drinking plenty of water can help flush out the bacterial infection faster and manage any side effects like diarrhoea that may occur with Magnex 1g Injection.
Avoid alcohol: Since Magnex 1g Injection is an antibiotic, it's important to abstain from alcohol during your course of medication. Alcohol can interfere with the medication's effectiveness and exacerbate side effects.

Fact Box

Drug Category	Cell Wall Synthesis Inhibitor, Beta-Lactamase Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Ear Infections, Throat Infections, Urinary Tract Infections

What is Magnex 1g Injection used for?

Magnex 1g Injection is used to manage a broad range of bacterial infections like those affecting the ears, lungs, skin, and urinary tract.

How does Magnex 1g Injection work?

It contains cefoperazone and sulbactam. Cefoperazone inhibits bacterial cell wall synthesis, while sulbactam reduces bacterial resistance, enhancing the effect of cefoperazone.

How is Magnex 1g Injection administered?

Magnex 1g Injection is administered intravenously by a doctor. It should be infused slowly over a period of 15 to 60 minutes.

Are there any side effects of using Magnex 1g Injection?

Common side effects include nausea, vomiting, diarrhoea, pain at the injection site, and allergic reactions. Severe reactions should be reported to your doctor immediately.

Who should avoid using Magnex 1g Injection?

It should be avoided by people allergic to cefoperazone, sulbactam or other similar antibiotics. Also, those with liver or kidney dysfunction should use it cautiously.

Can I take this medication if I'm pregnant or breastfeeding?

The safety isn't established for use during pregnancy and lactation. Always consult your doctor before using any medication in these conditions.

Are there any precautions to take while using Magnex 1g Injection?

Yes, stay hydrated, avoid alcohol during treatment and inform your doctor about any other medications you are taking including over-the-counter medicines and herbal supplements.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Plot No. C, The Capital, 1802, 18th Floor, 70, G Block Rd, Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra 400051

Country of origin: INDIA

References

Sulbactam: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09324
PubChem. (n.d.). Sulbactam. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/130313
CefOperaZone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01329
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 44187, Cefoperazone. Retrieved June 11, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Cefoperazone

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