Macsita M 50050 Mg Tablet 10

Macsita M Xr 50/500 Tablet 10

Q: What is Macsita M Xr 50/500 Tablet 10 used for?

Macsita M Xr 50/500 Tablet 10 is used to manage blood sugar levels in adults with type 2 diabetes in conjunction with diet, exercise, and weight control.

Q: How do the ingredients in Macsita M Xr 50/500 Tablet 10 work?

Metformin reduces glucose production in the liver, intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin helps increase insulin synthesis and release.

Q: What happens if I miss a Dose of Macsita M Xr 50/500 Tablet 10?

If it's almost time for your next dose, skip the one you missed. Don't double your dose to make up for the missed one.

Q: Can I take Macsita M Xr 50/500 Tablet 10 during pregnancy?

Macsita M Xr 50/500 Tablet 10 is not advised during pregnancy as it may harm the unborn baby. Always consult your doctor before use.

Q: Should I be aware of any side effects of Macsita M Xr 50/500 Tablet 10?

Common side effects may include diarrhoea, upper respiratory tract infection, headache, nausea, vomiting, gas, and weakness. Consult your doctor if they persist or worsen.

Q: Are there any precautions I should take while using Macsita M Xr 50/500 Tablet 10?

Use this medicine with caution if you have heart problems, liver impairment, or vitamin B12 deficiency. Alcohol use should be minimised.

Q: How should I store my Macsita M Xr 50/500 Tablet 10?

Store your tablet at a temperature not exceeding 30°C, away from light, moisture, and children's reach.

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Composition

Metformin (500 Mg) + Sitagliptin (50 Mg)

Macsita M Xr 50/500 Tablet 10 is primarily used to manage blood sugar levels in adults with type 2 diabetes. This combination medicine falls under the category of antidiabetic medications.

Beyond blood sugar control, it helps stabilise both fasting and post-meal glucose levels when used as part of a comprehensive diabetes management plan. This plan typically includes medication, diet, exercise, and weight management.

For optimal results, it's essential to take this medicine as directed by your doctor. Ensure your doctor is informed about any existing health conditions or medications before starting treatment. If you experience any side effects, contact your doctor immediately. Continue taking the medicine for the prescribed duration to maintain proper blood sugar control.

Macsita M Xr 50/500 Tablet 10 is used for the following:

Managing blood sugar levels in adults with type 2 diabetes
Improving glycemic control when lifestyle modifications like diet and exercise are not enough
Combating both fasting and post-meal blood sugar spikes
Aiding in the comprehensive management of type 2 diabetes when both sitagliptin and metformin are suitable for treatment

Directions for Use of Macsita M Xr 50/500 Tablet 10

Swallow the tablet whole with a glass of water.
Do not crush, chew, or split the tablet.
Always stick to the dose recommended by your doctor, and do not alter it on your own.

Macsita M Xr 50/500 Tablet 10 is taken orally.

Side Effects of Macsita M Xr 50/500 Tablet 10

Macsita M Xr 50/500 Tablet 10 may cause the following common side effects:

Diarrhoea
Headache
Nausea
Vomiting
Weakness
Upper respiratory tract infection
Gas and bloating
Indigestion

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Macsita M Xr 50/500 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Macsita M Xr 50/500 Tablet 10 with food or milk to lessen this effect.
Indigestion: If you have indigestion, take this medicine after meals to lessen this effect.

How Macsita M Xr 50/500 Tablet 10 Works?

Macsita M Xr 50/500 Tablet 10 has two active ingredients that work together to manage type 2 diabetes:

Sitagliptin (50 mg): Sitagliptin maintains the levels of incretin hormones (GLP-1 and GIP) in your body. These hormones help stimulate insulin synthesis and release after meals, which aids in controlling post-meal blood sugar spikes.
Metformin (500 mg): This component works by reducing the production of glucose in your liver, decreasing the absorption of glucose in your gut, and improving insulin sensitivity. This combined action results in lower blood sugar levels.

Pregnancy

Caution is advised while taking Macsita M Xr 50/500 Tablet 10 if you are pregnant. It's best to consult your doctor before taking this medicine, as poorly managed blood sugars can harm the foetus.

Breastfeeding

The safety of this medicine during breastfeeding is not fully established. It's recommended to discuss this with your doctor before using Macsita M Xr 50/500 Tablet 10 if you're breastfeeding.

Alcohol

You are advised to limit your alcohol intake while taking Macsita M Xr 50/500 Tablet 10. Alcohol may increase the risk of lactic acidosis, a potential side effect of metformin.

Liver

If you have liver problems or elevated liver enzymes, caution is needed when taking Macsita M Xr 50/500 Tablet 10. Before you start on this medication, discuss your liver health with your doctor.

Kidney

Macsita M Xr 50/500 Tablet 10 is contraindicated in severe renal impairment conditions. If you have a history of kidney problems, it's crucial to consult your doctor before starting this medication.

Using Machines & Driving

No specific precautions exist regarding driving or operating heavy machinery while taking Macsita M Xr 50/500 Tablet 10. However, if you feel dizzy or unwell after taking the medicine, avoid these activities.

Allergy

This medicine is contraindicated if you have a known hypersensitivity to metformin or sitagliptin. If you've had allergic reactions to similar medicines in the past, inform your doctor before starting this medication.

Children

Macsita M Xr 50/500 Tablet 10 is meant for adult use and should not be given to children under 18 years of age unless prescribed by a doctor.

Older Patients

Older patients may need close monitoring while taking Macsita M Xr 50/500 Tablet 10 due to potential side effects and co-existing health conditions. Your doctor will guide you based on your health status.

Interactions of Macsita M Xr 50/500 Tablet 10

Drug-Drug Interactions

Macsita M Xr 50/500 Tablet 10 interacts with the following medicines:

Carbonic anhydrase inhibitors: Medications such as acetazolamide or methazolamide may interact with Macsita M Xr 50/500 Tablet 10, increasing the risk of lactic acidosis due to metformin.
Insulin and insulin secretagogues: When taken with Macsita M Xr 50/500 Tablet 10, insulin and sulfonylureas like glimepiride or glibenclamide can cause low blood sugar (hypoglycaemia).
Cationic medicines: Medicines like amiloride or quinidine, which are excreted via renal tubular secretion, may interact with Macsita M Xr 50/500 Tablet 10, leading to an accumulation of metformin.
Diuretics: Furosemide may increase plasma levels of metformin when used with Macsita M Xr 50/500 Tablet 10, enhancing its blood glucose-lowering effect.
Calcium channel blockers: Nifedipine may interact with Macsita M Xr 50/500 Tablet 10, leading to increased absorption and peak concentration (Cmax) of metformin.

Drug-Food Interactions

None

Drug-Disease Interactions

Macsita M Xr 50/500 Tablet 10 interacts with the following diseases:

Renal impairment: Patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²) should avoid Macsita M Xr 50/500 Tablet 10 due to the risk of medicine accumulation and potential toxicity.
Liver disease: Patients with liver disease should use Macsita M Xr 50/500 Tablet 10 cautiously, as it may impact the metabolism of the medication.
Congestive heart failure: Those with heart failure requiring medication should exercise caution when taking Macsita M Xr 50/500 Tablet 10, as it may worsen their condition.
Vitamin B12 deficiency: The metformin component in Macsita M Xr 50/500 Tablet 10 can reduce Vitamin B12 levels; therefore, individuals with a deficiency should be monitored closely.
Hypoxic states: Conditions like cardiovascular collapse (shock) can increase the risk of lactic acidosis, necessitating careful monitoring when using Macsita M Xr 50/500 Tablet 10.

Daily Dose

You should take Macsita M Xr 50/500 Tablet 10 as instructed by your doctor. The dosage can vary based on your individual health condition and response to the medication.

Over Dose

If you accidentally take more Macsita M Xr 50/500 Tablet 10 than prescribed, you may experience symptoms like nausea, weakness, or diarrhoea. If these symptoms occur, kindly consult your doctor.

Missed Dose

If you miss a dose of Macsita M Xr 50/500 Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Store Macsita M Xr 50/500 Tablet 10 at a temperature not exceeding 30°C.
Protect from light and moisture.
Keep out of reach of children.

Incorporating at least 30 minutes of regular physical activity into your daily routine is essential for managing blood sugar levels effectively.
Adopting a balanced diet that is low in sugar and high in fibre is crucial for controlling blood sugar spikes and enhancing the effectiveness of Macsita M Xr 50/500 Tablet 10.

Fact Box

Drug Category	Glucose Regulator
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is Macsita M Xr 50/500 Tablet 10 used for?

Macsita M Xr 50/500 Tablet 10 is used to manage blood sugar levels in adults with type 2 diabetes in conjunction with diet, exercise, and weight control.

How do the ingredients in Macsita M Xr 50/500 Tablet 10 work?

Metformin reduces glucose production in the liver, intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin helps increase insulin synthesis and release.

What happens if I miss a Dose of Macsita M Xr 50/500 Tablet 10?

If it's almost time for your next dose, skip the one you missed. Don't double your dose to make up for the missed one.

Can I take Macsita M Xr 50/500 Tablet 10 during pregnancy?

Macsita M Xr 50/500 Tablet 10 is not advised during pregnancy as it may harm the unborn baby. Always consult your doctor before use.

Should I be aware of any side effects of Macsita M Xr 50/500 Tablet 10?

Common side effects may include diarrhoea, upper respiratory tract infection, headache, nausea, vomiting, gas, and weakness. Consult your doctor if they persist or worsen.

Are there any precautions I should take while using Macsita M Xr 50/500 Tablet 10?

Use this medicine with caution if you have heart problems, liver impairment, or vitamin B12 deficiency. Alcohol use should be minimised.

How should I store my Macsita M Xr 50/500 Tablet 10?

Store your tablet at a temperature not exceeding 30°C, away from light, moisture, and children's reach.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

Sitagliptin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a606023.html
Metformin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html
About sitagliptin. (2022, February 15). NHS. https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/
Metformin: Uses, Interactions, Mechanism of Action. (n.d.). DrugBank Online. https://go.drugbank.com/drugs/DB00331
Metformin information. (2016, March 30). U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/metformin-information

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