Macgyl O 50100 Mg Syrup 30 Ml

Macgyl O 50/100 MG Syrup 30 ML

Torque Pharmaceuticals Pvt Ltd

Bottle of 30 ML

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₹51.66

₹2.10/ML

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Composition

Metronidazole (100 Mg) + Ofloxacin (50 Mg)

Macgyl O 50/100 MG Syrup 30 ML is primarily used for managing diarrhoea caused by mixed bacterial infections in adults. This medicine is a combination of two active ingredients that belong to the class of antibiotics.

In addition to its primary use, this suspension also provides coverage against a broad spectrum of bacteria responsible for various infections. This makes it effective in managing other bacterial infections, apart from diarrhoea, that are sensitive to its components.

It's crucial that you take this medicine as directed by your doctor. The doctor will determine the appropriate dosage and frequency based on your condition. Before starting on this medication, inform your doctor about any pre-existing health conditions or ongoing medications. If you notice any side effects while taking this medicine, notify your doctor promptly. Continue taking the medicine for the duration prescribed by your doctor to achieve the best results.

Macgyl O 50/100 MG Syrup 30 ML is beneficial for managing the following health conditions:

Managing diarrhoea caused by a wide range of bacteria.
Managing mixed-bacterial infections leading to diarrhoea.

Directions for Use of Macgyl O 50/100 MG Syrup 30 ML

To ensure effective use of Macgyl O 50/100 MG Syrup 30 ML, follow these guidelines:

Give the bottle a good shake before using it.
Measure the exact quantity as advised by your doctor using a spoon or cup.
You can take this medicine with or without food.
Always consult your doctor for specific instructions on using Macgyl O 50/100 MG Syrup 30 ML.

Macgyl O 50/100 MG Syrup 30 ML is taken orally.

Side Effects of Macgyl O 50/100 MG Syrup 30 ML

Macgyl O 50/100 MG Syrup 30 ML may have the following common side effects:

Nausea
Vomiting
Abdominal pain
Diarrhoea
Metallic taste: This refers to a strange or unusual taste in your mouth.
Headache
Dizziness
Insomnia: This refers to difficulty falling asleep or staying asleep.

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Macgyl O 50/100 MG Syrup 30 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Macgyl O 50/100 MG Syrup 30 ML with food or milk.
Metallic taste: Drinking citrus juices like orange or lemon juice after taking the medicine might help reduce this side effect.

How Macgyl O 50/100 MG Syrup 30 ML Works?

Macgyl O 50/100 MG Syrup 30 ML contains two active components:

Ofloxacin (50 mg): Ofloxacin is a fluoroquinolone antibiotic. It acts by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By inhibiting these enzymes, ofloxacin causes inhibition of bacterial cell division and cell death.
Metronidazole (100 mg): Metronidazole is a nitroimidazole antibiotic. It works by inhibiting the synthesis of bacterial DNA and causing DNA damage, which ultimately leads to bacterial cell death. It's particularly effective against anaerobic bacteria and protozoa.

The combination of these two antibiotics in Macgyl O 50/100 MG Syrup 30 ML provides a synergistic effect in effectively managing a wide range of bacteria responsible for causing diarrhoea in adults.

Pregnancy

Caution is advised while taking Macgyl O 50/100 MG Syrup 30 ML if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, make sure to discuss this with your doctor before starting this medicine.

Alcohol

Avoid consuming alcohol while on Macgyl O 50/100 MG Syrup 30 ML, as it might interfere with the effectiveness of the medication. Consult your doctor for more details.

Liver

Caution is advised while taking Macgyl O 50/100 MG Syrup 30 ML in case of mild to moderate liver impairment. It's not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Macgyl O 50/100 MG Syrup 30 ML.

Kidney

If you have a history of any kidney problems, it's a good idea to consult your doctor before taking Macgyl O 50/100 MG Syrup 30 ML.

Using Machines & Driving

Macgyl O 50/100 MG Syrup 30 ML may cause dizziness or vertigo. Therefore, avoid driving or operating heavy machinery until you know how this medicine affects you.

Allergy

If you are allergic to metronidazole, ofloxacin, or any other component of Macgyl O 50/100 MG Syrup 30 ML, avoid using this medicine. Always inform your doctor about your allergies.

Children

Macgyl O 50/100 MG Syrup 30 ML is generally safe for use in children under medical supervision. However, always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Macgyl O 50/100 MG Syrup 30 ML under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Macgyl O 50/100 MG Syrup 30 ML

Drug-Drug Interactions

Macgyl O 50/100 MG Syrup 30 ML Interacts with the Following Medicines:

Anticoagulants: Metronidazole in Macgyl O 50/100 MG Syrup 30 ML may enhance the effect of medicines like warfarin, making your blood clot more slowly.
Mineral supplements: The absorption of ofloxacin in Macgyl O 50/100 MG Syrup 30 ML can be reduced if taken with iron supplements or multivitamins that contain zinc. These should be taken at least 2 hours before or after Macgyl O 50/100 MG Syrup 30 ML.
Respiratory medications: When taken together, ofloxacin can increase the levels of a respiratory medicine called theophylline in your body.

Drug-Food Interactions

Macgyl O 50/100 MG Syrup 30 ML has no known interactions with any specific foods.

Drug-Disease Interactions

Macgyl O 50/100 MG Syrup 30 ML interacts with the following diseases:

Central nervous system disorders: If you have conditions affecting your nervous system, such as epilepsy or seizures, metronidazole in Macgyl O 50/100 MG Syrup 30 ML could potentially worsen your symptoms.
Heart disease: Ofloxacin can cause an irregular heartbeat or QT prolongation, which could be a concern if you have heart conditions.
Liver disease: As metronidazole is metabolised primarily in the liver, patients with liver disease may need careful monitoring while taking Macgyl O 50/100 MG Syrup 30 ML.

Dosage of Macgyl O 50/100 MG Syrup 30 ML

Daily Dose

The daily dose of Macgyl O 50/100 MG Syrup 30 ML should be as prescribed by your doctor. The dosage may vary based on individual factors such as the severity of the condition and response to treatment. It is vital to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you accidentally take more Macgyl O 50/100 MG Syrup 30 ML than recommended, you might experience common symptoms like nausea, abdominal pain, or dizziness. However, do not panic. Inform your doctor about the condition.

Missed Dose

If you forget to take your regular dose of Macgyl O 50/100 MG Syrup 30 ML, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Don't increase your dosage without consulting your doctor.

Keep Macgyl O 50/100 MG Syrup 30 ML stored in a cool and dry place.
Protect it from light and keep the bottle tightly closed.
Avoid exposure to moisture and excessive heat.
Always make sure it's out of reach of children.
Remember to use the medicine before its expiry date.

Follow a balanced diet rich in fruits, vegetables, lean protein, and whole grains to boost your immune system.
A lifestyle change to consider is maintaining proper hygiene practices like washing your hands regularly and thoroughly, especially before meals. This can help prevent bacterial infections from spreading or recurring.

Fact Box

Drug Category	Nitroimidazole Antibiotic, Fluoroquinolone Antibiotic
Therapeutic Category	Antibiotic
Available Dosage Types	Suspension
Habit Forming	No
Ailment	Bacterial Diarrhoea, Mixed Bacterial Infections

What is Macgyl O 50/100 MG Syrup 30 ML used for?

Macgyl O 50/100 MG Syrup 30 ML is used to manage diarrhoea caused by mixed bacterial infections in adults.

What are the active ingredients in Macgyl O 50/100 MG Syrup 30 ML?

The active ingredients in Macgyl O 50/100 MG Syrup 30 ML are metronidazole and ofloxacin.

How does Macgyl O 50/100 MG Syrup 30 ML work?

Metronidazole and ofloxacin in Macgyl O 50/100 MG Syrup 30 ML work by inhibiting the growth and replication of bacteria, thereby managing the infection.

Can Macgyl O 50/100 MG Syrup 30 ML be taken with food?

Yes, Macgyl O 50/100 MG Syrup 30 ML can be taken with or without food. Always shake the bottle well before use.

Who should avoid taking Macgyl O 50/100 MG Syrup 30 ML?

Individuals allergic to metronidazole or ofloxacin, or those with a history of seizures or tendon problems should avoid taking this medicine.

Are there any side effects of Macgyl O 50/100 MG Syrup 30 ML?

Possible side effects include nausea, insomnia, rash, and rarely, seizures. Consult your doctor if you experience any adverse effects.

Does Macgyl O 50/100 MG Syrup 30 ML interact with other medicines?

Yes, it may interact with medicines like warfarin, antacids, iron supplements, and theophylline. Always consult your doctor before starting any new medication.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

693 PHASE II INDUSTRIAL AREA CHANDIGARH CH 160002 IN

Country of origin: INDIA

References

Dailymed. (n.d.). METRONIDAZOLE - metronidazole tablet. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=23927a8b-1641-4104-aa85-d7b7bf4ebb9d
U.S. Food and Drug Administration. (2020). Drug Approval Package: Xifaxan (rifaximin) NDA #021361. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/201699s012lbl.pdf
U.S. Food and Drug Administration. (n.d.). 207986-Ciprofloxacin-Clinical-PREA. Retrieved 1 April 2024, from https://www.fda.gov/files/drugs/published/207986-Ciprofloxacin-Clinical-PREA.pdf
Metronidazole Connor B. Weir; Jacqueline K. Le. https://www.ncbi.nlm.nih.gov/books/NBK539728/
Metronidazole. https://medlineplus.gov/druginfo/meds/a689011.html

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