Macalvit Injection 15 Ml

Macalvit Injection 15 ML

Novartis India Ltd

Pack of 15 ML

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MRP ~~₹81.81~~

₹67.08

₹5.45/ML

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Composition

Other Calcium + Vit D3 (Cholecalciferol)

Macalvit Injection is primarily used to manage calcium and vitamin D deficiencies in individuals who may not receive sufficient amounts through diet or sunlight exposure. This medication belongs to a class of medicines known as calcium and vitamin D supplements, making it a combination medicine.

This medicine is also used in situations where the body's ability to absorb or activate these essential nutrients is impaired. These may include conditions such as osteoporosis, osteomalacia, hypoparathyroidism, chronic kidney disease, long-term corticosteroid therapy, and certain gastrointestinal disorders that can interfere with nutrient absorption.

It is important to inform your doctor about any existing medical conditions or ongoing medications before starting this medicine. If you notice any side effects while using this medicine, notify your doctor immediately. For best results, continue using the medicine for the duration prescribed by your doctor.

Macalvit Injection is used for the following:

Management of calcium and vitamin D deficiencies
Support for patients with osteoporosis or osteomalacia
Assistance for individuals with hypoparathyroidism
Care for chronic kidney disease patients who are unable to activate vitamin D properly
Aid for patients on corticosteroid therapy, which can lead to bone loss
Support for individuals with malabsorption syndromes or gastrointestinal disorders that hinder calcium and vitamin D absorption

Directions for Use of Macalvit Injection 15 ML

Macalvit Injection is administered by a healthcare professional, either intramuscularly or intravenously.
It's crucial to follow the doctor's prescribed dosage and frequency.
It's recommended that you maintain an adequate intake of calcium and vitamin D through diet and sunlight exposure, as advised by your doctor.

Macalvit Injection is administered intramuscularly or intravenously.

Side Effects of Macalvit Injection 15 ML

Like all medications, Macalvit Injection can have some possible side effects. However, not everyone will experience them. Common side effects include:

Nausea and vomiting
Diarrhoea or constipation
Abdominal pain or discomfort
Headache
Dizziness
Injection site reactions: This could include pain, redness, or swelling at the spot where the injection was administered.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Macalvit Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a few tips to manage common side effects:

Nausea and vomiting: Try taking the injection after meals to lessen these effects.
Abdominal pain or discomfort: Maintaining a balanced diet could help to manage this side effect.

Macalvit Injection contains two active ingredients that work together to manage calcium and vitamin D deficiencies:

Calcium: This essential mineral plays a vital role in maintaining the health of your bones, teeth, heart, muscles, and nerves. It helps in building and maintaining strong bones and teeth, and in ensuring the proper functioning of your heart, muscles, and nerves.
Vitamin D3 (Cholecalciferol): A fat-soluble vitamin, it aids in the absorption of calcium from your gut and helps regulate calcium levels in your blood. This vitamin also assists in the absorption of another essential mineral, phosphorus, which contributes to bone health.

Together, these ingredients increase calcium absorption, maintain proper calcium levels, and support overall bone health. They ensure that your body has the necessary levels of these nutrients even when dietary intake or sunlight exposure is insufficient.

Pregnancy

Caution is advised while taking Macalvit Injection if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, please consult your doctor before using Macalvit Injection.

Alcohol

Caution is advised when consuming alcohol if Macalvit Injection is prescribed to you.

Liver

While taking Macalvit Injection, precaution should be exercised if you have liver problems. Discuss this with your doctor before starting the medicine.

Kidney

If you have kidney health issues, it is advised to consult your doctor before using Macalvit Injection.

Using Machines & Driving

Macalvit Injection does not usually affect your ability to drive or operate machinery. However, if you feel dizzy or unwell after the injection, avoid these activities and rest instead.

Allergy

If you are allergic to calcium or vitamin D3 (cholecalciferol) or any other ingredients in Macalvit Injection, inform your doctor.

Children

The safety and efficacy of Macalvit Injection in children have not been established. Therefore, always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should use Macalvit Injection under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Macalvit Injection 15 ML

Drug-Drug Interactions

Macalvit Injection interacts with the following medicines:

Thiazide Diuretics: Medicines like hydrochlorothiazide may enhance the risk of high blood calcium levels (hypercalcemia) when taken with Macalvit Injection.
Digitalis Glycosides: Medicines such as digoxin can have increased toxicity due to hypercalcemia, potentially caused by Macalvit Injection.
Corticosteroids: These medications, like prednisone, may decrease the absorption and effectiveness of vitamin D in Macalvit Injection.
Anticonvulsants: Medications like phenytoin or phenobarbital may speed up the metabolism of vitamin D, reducing its effectiveness when used with Macalvit Injection.

Drug-Food Interactions

Drug-Disease Interactions

Macalvit Injection interacts with the following diseases:

Hypercalcemia or Hypercalciuria: If you have high blood or urine calcium levels, use of this medicine should be done with caution as it might exacerbate your condition.
Kidney Stones or Impaired Kidney Function: This medicine can increase calcium levels, which might lead to kidney stone formation in susceptible individuals.
Sarcoidosis or Other Granulomatous Diseases: In these conditions, there is an increased risk of hypercalcemia and thus requires caution while using this medicine.
Malignancy with Bone Metastases: There's a chance that this medicine might increase calcium levels in your blood if you have cancer that has spread to your bones.

Daily Dose

Your doctor will advise you on how often to administer Macalvit Injection, based on the severity of your condition and how you respond to the medicine. Always follow your doctor's instructions carefully.

Over Dose

An overdose is highly unlikely for this medication as a healthcare professional administers it.

Missed Dose

If you forget to get a dose of this injection as scheduled, consult with your doctor for advice.

Store Macalvit Injection at room temperature.
Keep it away from direct light and moisture to maintain its effectiveness.
Always keep this medicine out of the reach and sight of children.
Make sure to check the expiry date mentioned on the pack.

Aim to incorporate a balanced diet rich in calcium and vitamin D. Foods like dairy products, fish, and leafy greens can provide a good source of these nutrients.
Regular, gentle weight-bearing exercises such as walking or climbing stairs can support bone health, particularly if you have osteoporosis or osteomalacia which are managed by Macalvit Injection. Consult your doctor for an exercise routine that suits you.

Fact Box

Drug Category	Calcium Absorption Enhancer
Therapeutic Category	Nutritional Supplement
Available Dosage Types	Injection
Habit Forming	No
Ailment	Osteoporosis, Hypoparathyroidism, Chronic Kidney Disease

What is Macalvit Injection used for?

Macalvit Injection is used to manage calcium and vitamin D3 deficiencies in adults who may not receive enough from their diet or sun exposure.

How does Macalvit Injection work?

It combines calcium and vitamin D3 which work together to increase calcium absorption, maintain its proper levels, and support bone health.

Can Macalvit Injection be used for osteoporosis?

Yes, it is often used to manage calcium and vitamin D deficiencies in patients with osteoporosis or osteomalacia (softening of bones).

Are there any side effects of Macalvit Injection?

Some common side effects include nausea, vomiting, diarrhoea, abdominal discomfort, headache, dizziness, and reactions at the injection site.

Who should not use Macalvit Injection?

Individuals with high blood or urine calcium levels, kidney stones, certain diseases like sarcoidosis, or severe hypercalcemia should avoid using Macalvit Injection.

Can Macalvit Injection interact with other medicines?

Yes, it can interact with medications like thiazide diuretics, digitalis glycosides (digoxin), corticosteroids, anticonvulsants (phenytoin, phenobarbital), cholestyramine and colestipol.

How should I store Macalvit Injection?

Store it at room temperature away from direct light, heat and moisture. Don't freeze it, and discard any unused portion as per the manufacturer's instructions.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

The Inspire BKC Part 601 & 701 Bandra Kurla Complex Bandra(E) Mumbai - India

Country of origin: INDIA

References

Sunyecz, J. A. (2008). The use of calcium and vitamin D in the management of osteoporosis. Therapeutics and Clinical Risk Management, Volume 4, 827–836. https://doi.org/10.2147/tcrm.s3552
Khazai, N., Judd, S. E., & Tangpricha, V. (2008). Calcium and vitamin D: Skeletal and extraskeletal health. Current Rheumatology Reports, 10(2), 110–117. https://doi.org/10.1007/s11926-008-0020-y
Voulgaridou, G., Papadopoulou, S. K., Detopoulou, P., Tsoumana, D., Giaginis, C., Kondyli, F. S., Lymperaki, E., & Pritsa, A. (2023). Vitamin D and Calcium in Osteoporosis, and the Role of Bone Turnover Markers: A Narrative Review of Recent Data from RCTs. Diseases, 11(1), 29. https://doi.org/10.3390/diseases11010029
Dawson-Hughes, B. (2004). Calcium and vitamin D for bone health in adults. In Humana Press eBooks (pp. 197–210). https://doi.org/10.1007/978-1-59259-740-6_12

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