Lyros F Tablet 10

Leenate Pharma Private Limited

Strip of 10 Units

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Composition

Fenofibrate (145 Mg) + Rosuvastatin (10 Mg)

Lyros F Tablet 10 is primarily used to manage high blood lipid levels, which are commonly known as hyperlipidemia. This combination medicine belongs to the class of medications known as statins and fibric acid derivatives.

Apart from controlling hyperlipidemia, this tablet is beneficial in managing primary hypercholesterolemia (both familial and nonfamilial) and mixed dyslipidemia, particularly when diet and other non-pharmacological measures don't deliver sufficient results. Moreover, this medicine can reduce the risk of cardiovascular disease in patients with type 2 diabetes who have multiple risk factors but no noticeable coronary heart disease.

Before starting on this medication, it's crucial to consult your doctor who'll guide you on the appropriate dose and frequency. Don't forget to inform your doctor about any ongoing medications or pre-existing conditions you have. If you notice any side effects while using this medicine, notify your doctor immediately.

Lyros F Tablet 10 is used for the following:

Managing high blood cholesterol levels and mixed dyslipidemia: This is when diet and other non-pharmacological measures do not provide adequate results.
Handling high triglyceride levels: This medicine comes into play when a diet-focused approach is insufficient.
Reducing the risk of heart diseases in patients with type 2 diabetes: These are individuals who have multiple risk factors but no clinically evident coronary heart disease.

Swallow the tablet whole with a glass of water.
It's important not to crush, chew or break the tablet.
Always take your medicine at the same time each day.
Do not take more than the recommended dose without consulting your doctor.
Remember not to stop taking this medicine without speaking to your doctor first.

Lyros F Tablet 10 is taken orally.

Lyros F Tablet 10 may have the following common side effects:

Headache
Abdominal pain
Nausea
Constipation
Myalgia: This is a medical term for muscle pain.
Asthenia: This means you might feel weak or tired.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Lyros F Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: It can help to take Lyros F Tablet 10 with food or milk.
Myalgia: If you experience muscle pain, consider taking this medicine at night.

The effectiveness of Lyros F Tablet 10 comes from its two active ingredients:

Fenofibrate (145 mg): This component works by activating a specific receptor in your body called peroxisome proliferator-activated receptor α (PPAR-α). This action enhances the breakdown of triglyceride-rich particles and boosts the production of HDL or "good" cholesterol. Additionally, fenofibrate increases the activity of an enzyme called lipoprotein lipase and reduces the production of a substance known as apolipoprotein C-III, resulting in lower levels of triglycerides.
Rosuvastatin (10 mg): This component acts by competitively inhibiting HMG-CoA reductase – an enzyme directly involved in cholesterol production. This inhibition reduces cholesterol production in your body. Rosuvastatin also increases the number of LDL receptors on the cell surface in your liver, which leads to enhanced uptake and breakdown of LDL or "bad" cholesterol. By inhibiting the hepatic synthesis of VLDL, it also reduces the overall number of VLDL and LDL particles in your body.

Pregnancy

Use Lyros F Tablet 10 with caution if you are pregnant. It's always wise to consult your doctor before taking this medicine during pregnancy.

Breastfeeding

Lyros F Tablet 10 is not recommended for breastfeeding women. Discuss the potential risks and benefits with your doctor before taking this medicine while nursing.

Alcohol

Alcohol may enhance the risk of liver damage when taken with Lyros F Tablet 10. It's better to avoid alcohol while taking this medication.

Liver

This medicine should be used with caution if you have mild or moderate liver problems. If you have severe liver disease, Lyros F Tablet 10 is contraindicated. Discuss your liver health with your doctor before starting this medication.

Kidney

If you have kidney issues, it's important to exercise caution before using Lyros F Tablet 10. Consult your doctor for advice tailored to your health status.

Using Machines & Driving

There's no specific data about using machines or driving while taking Lyros F Tablet 10. But if you feel dizzy or unwell after taking it, avoid these activities and consult your doctor.

Allergy

Do not take Lyros F Tablet 10 if you're allergic to fenofibrate, rosuvastatin, or any other ingredients in the tablet. Inform your doctor about any known allergies before starting this medicine.

Children

Lyros F Tablet 10 is not recommended for use in children under 18 years of age. Always consult a doctor before giving this medication to a child.

Older Patients

Older patients should use Lyros F Tablet 10 with caution as they might be more susceptible to its side effects, especially those related to liver and kidney health. Remember, if you're over 70, it's best to take this medicine under medical supervision. Your doctor will guide you based on your overall health conditions.

Drug-Drug Interactions

Lyros F Tablet 10 interacts with the following medicines:

Lipid Regulating Medicines: Medicines like gemfibrozil can interact with the cytochrome P450 enzymes when taken alongside Lyros F Tablet 10.
Bile Acid Sequestrants: These medicines (like cholestyramine or colestipol) can interfere with the absorption of fenofibrate in Lyros F Tablet 10.
CYP2C9 Inhibitors: Medicines like fluconazole can increase rosuvastatin exposure when used with Lyros F Tablet 10.

Drug-Food Interactions

Grapefruit: Consuming grapefruit juice while taking this medication can increase the risk of side effects.

Drug-Disease Interactions

Lyros F Tablet 10 interacts with the following diseases:

Liver Disease: Patients with active liver disease or unexplained persistent elevations of serum transaminases should avoid Lyros F Tablet 10.
Severe Renal Impairment: Individuals with severe renal problems should not use this medicine.
Gallbladder Disease: Patients with preexisting gallbladder disease should exercise caution while using this medicine.

Daily Dose

Take the dose of Lyros F Tablet 10 as prescribed by your doctor. The dosage can vary depending on factors such as how severe your condition is and how you respond to the medicine. Always follow the dosage instructions given by your doctor, and avoid changing the dosage without consulting them first.

Over Dose

Overdosing on Lyros F Tablet 10 could potentially lead to some common side effects becoming more pronounced. If you suspect an overdose, it’s important to inform your doctor, who can provide appropriate advice and care.

Missed Dose

If you forget to take a dose of Lyros F Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Don't adjust the dosage without discussing it with your doctor.

Keep Lyros F Tablet 10 in its original packaging to protect it from light and moisture.
Store the medicine at room temperature between 15°C and 30°C.
Ensure it is stored out of reach of children.
Always check the expiry date before use. Do not use it if expired.

Incorporate a low-fat, low-cholesterol diet into your daily routine. This can help manage hyperlipidemia, which Lyros F Tablet 10 is used to help control.
Regular physical activity is crucial. Aim for moderate-intensity exercises like brisk walking or cycling for at least 150 minutes a week. Exercise aids in maintaining a healthy lipid profile, supporting the benefits of Lyros F Tablet 10.

Fact Box

Drug Category	PPAR-α Activator, HMG-CoA Reductase Inhibitor
Therapeutic Category	Lipid-Lowering Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypercholesterolemia, Hypertriglyceridemia

What is Lyros F Tablet 10 used for?

Lyros F Tablet 10 is used to manage high blood lipid levels, reducing the risk of heart diseases and stroke when combined with a proper diet and exercise.

How does Lyros F Tablet 10 work?

Lyros F Tablet 10 works by combining two active ingredients that help reduce bad cholesterol levels, increase good cholesterol, and decrease triglyceride levels in the blood.

Can I take this medicine with food?

Yes, Lyros F Tablet 10 can be taken with or without food as prescribed by the doctor. However, it's recommended to take it at the same consistent time each day.

What should I do if I miss a dose of Lyros F Tablet 10?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule.

Can I stop taking Lyros F Tablet 10 if my cholesterol levels improve?

No, you should continue taking Lyros F Tablet 10 as prescribed by your doctor, even if your cholesterol levels have improved.

What should I do if I experience muscle pain while taking this medicine?

If you have unexplained muscle pain or weakness, especially with fever or general ill feeling, inform your doctor immediately.

How should I store my Lyros F Tablet 10?

Store them at room temperature (15-30°C), away from moisture and light in a tightly closed container. Keep out of reach of children.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

S.C.F-446, 1St Floor, Motor Market, Manimajra, Chandigarh - 160101, India

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Fenofibrate: MedlinePlus Drug Information. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601052.html
U.S. National Library of Medicine. (2022). Rosuvastatin: MedlinePlus Drug Information. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a603033.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3339, Fenofibrate. Retrieved June 16, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Fenofibrate.
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 446157, Rosuvastatin. Retrieved June 16, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Rosuvastatin.
Balfour JA, McTavish D, Heel RC: Fenofibrate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia. Drugs. 1990 Aug;40(2):260-90. doi: 10.2165/00003495-199040020-00007. https://go.drugbank.com/articles/A185954

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