K Glim M 1500 Mg Tablet Pr 15

K Glim M 1mg Tablet 15

Blue Cross Laboratories Ltd

Strip of 15 Units

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Composition

Glimepiride (1 Mg) + Metformin (500 Mg)

K-Glim-M 1mg Tablet is primarily used to manage blood sugar levels in adults with type 2 diabetes. It's a combination medicine, belonging to the oral antidiabetic medicine class.

In addition to its main use, the tablet further aids in enhancing insulin sensitivity and reducing hepatic glucose output. These actions collectively help to improve glycemic control when coupled with an appropriate diet and regular exercise.

The medicine should be taken orally as directed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medication. If you notice any side effects while on this medicine, notify your doctor immediately. Ensure you continue taking the medicine for the entire duration prescribed by your doctor for optimal results.

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Directions for Use of K Glim M 1mg Tablet 15

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Take the medicine with your evening meal.
Always ensure you have enough fluids during the day to reduce risk of potential side effects.
If you forget to take a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose. Do not double doses.

K-Glim-M 1mg Tablet is taken orally.

Hypoglycaemia: This refers to low blood sugar levels, which can make you feel dizzy, sweaty, or shaky.
Diarrhoea
Upper respiratory tract infection: This is an infection that affects your nose, throat, and sinuses.

Additionally, there might be some less common side effects such as:

Serious hypersensitivity reactions: These are severe allergic reactions which may cause symptoms like swelling of the face, lips, tongue or throat.
Haemolytic Anaemia: This is a condition where your red blood cells get destroyed faster than they can be replaced.

Managing the Side Effects:

Hypoglycaemia: Try taking K-Glim-M 1mg Tablet with food to help manage this effect.
Diarrhoea: Make sure to stay well-hydrated if you're experiencing diarrhoea after taking this medicine.

K-Glim-M 1mg Tablet consists of the following two components:

Glimepiride (1 mg): This is a sulfonylurea that stimulates your pancreas to secrete more insulin. It works by binding to specific receptors on the pancreatic beta cells, which then closes certain potassium channels, resulting in more insulin being released.
Metformin (500 mg): This biguanide lowers hepatic glucose output by inhibiting gluconeogenesis and glycogenolysis – which are processes your body uses to produce glucose. It also increases insulin sensitivity, meaning it helps your body better utilise the insulin it produces or receives through medication. Lastly, metformin delays intestinal glucose absorption.

Pregnancy

If you're pregnant, caution is advised while taking K-Glim-M 1mg Tablet. This medicine may cause harm to the unborn baby. Please consult your doctor before taking this medication.

Breastfeeding

Breastfeeding is not recommended while taking this medicine. Consult your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol can intensify the risk of lactic acidosis and hypoglycemia when you're on K-Glim-M 1mg Tablet. It's best to limit alcohol consumption while taking this medicine.

Liver

In case of liver impairment, avoid using K-Glim-M 1mg Tablet. This medicine might affect liver function. If you have any liver-related issues, it's best to discuss them with your doctor before starting on this medication.

Kidney

K-Glim-M 1mg Tablet is contraindicated in individuals with severe renal impairment and not recommended for those with moderate impairment. If you have kidney health issues, discuss them with your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause hypoglycemia which could affect your ability to drive or operate machinery. If you experience symptoms such as dizziness or confusion, avoid these activities.

Allergy

If you're allergic to glimepiride, metformin or any other component of K-Glim-M 1mg Tablet, avoid using this medicine. Consult your doctor for an alternative medication.

Children

Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take K-Glim-M 1mg Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): These medicines, such as ibuprofen and naproxen, can affect blood glucose levels, potentially reducing the effectiveness of K-Glim-M 1mg Tablet.
Heart Medicines: Medicines like digoxin may interact with K-Glim-M 1mg Tablet, potentially affecting their absorption due to metformin's effect on gastrointestinal transit.
Diuretics: Medicines like amiloride and triamterene may compete for common renal tubular transport systems with metformin, potentially affecting its elimination from the body.

Drug-Food Interactions

There are no known food interactions with K-Glim-M 1mg Tablet.

Drug-Disease Interactions

Kidney Disease: People with severe kidney disease should not take K-Glim-M 1mg Tablet as it can build up in your body and cause lactic acidosis.
Liver Disease: Those with liver issues should avoid this medication as it might exacerbate their condition.
Metabolic Acidosis: If you have metabolic acidosis (including diabetic ketoacidosis), then you should not take K-Glim-M 1mg Tablet as it may worsen your condition.

Daily Dose

Your daily dose of K-Glim-M 1mg Tablet will be decided by your doctor based on factors such as the severity of your condition and how you respond to the medication. It's vital to stick to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

Overdosing on K-Glim-M 1mg Tablet could lead to symptoms such as dizziness, excessive sweating, or a rapid heartbeat. If these symptoms persist or worsen, it is advisable to inform your doctor.

Missed Dose

If you forget to take your K-Glim-M 1mg Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and stick to your regular schedule. Don't increase your dosage without consulting with your doctor.

Store the K-Glim-M 1mg Tablet in a cool, dry place, where the temperature is below 30°C.
Keep the tablet away from direct light and moisture.
Make sure to keep it out of reach of children.
Always use the tablet before its expiry date.

If you have been prescribed K-Glim-M 1mg Tablet, try to adopt a balanced diet that's low in refined sugars. This can help manage your blood glucose levels better.
Regular physical activity is also beneficial. It can increase insulin sensitivity and help your body use the glucose and insulin produced more effectively. Make sure your exercise routine is suitable for your age and health condition.

Fact Box

Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is K-Glim-M 1mg Tablet used for?

The K-Glim-M 1mg Tablet is used to manage blood sugar levels in adults with type 2 diabetes, alongside proper diet and exercise.

How does the medication work?

This medicine combines glimepiride and metformin, which work together to lower glucose levels. Glimepiride increases insulin production while metformin reduces glucose production in the liver.

Can I take it if I have kidney problems?

This medication is not recommended if you have severe kidney problems. Consult your doctor for alternatives.

What should I do if I miss a dose of K-Glim-M 1mg Tablet?

If you miss a dose, take it as soon as you remember. However, skip the missed dose if it's close to your next scheduled dose.

Is it safe to use during pregnancy?

If you're pregnant, caution is advised while taking K-Glim-M 1mg Tablet. This medicine may cause harm to the unborn baby. Please consult your doctor before taking this medication.

Can I crush or chew the tablet?

No, the K-Glim-M 1mg Tablet should be swallowed whole with water; crushing or chewing can affect how it works.

Does K-Glim-M 1mg Tablet cause any side effects?

Common side effects include low blood sugar (hypoglycaemia), diarrhoea, and upper respiratory tract infection. If any side effect bothers you or does not go away, consult your doctor.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Peninsula Corporate Park, Peninsula Chambers, G.K Marg, Lower Parel West, Lower Parel, Mumbai, Maharashtra 400013

Country of origin: INDIA

References

Unknown. (n.d.). Metformin hydrochloride Prolonged Release & Glimepiride tablets I.P. [Pharmaceutical Information]. https://www.sanofi.in/dam/jcr:6c1f15ea-d4af-4e93-b38c-91a76293b247/Amaryl%20M%20-%20PI.pdf
Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222

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