Justoza S 550 Tablet 10

Justoza S 5/50 Tablet 10

Mankind Pharmaceuticals Ltd.

Strip of 10 Units

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Composition

Dapagliflozin (5 Mg) + Sitagliptin (50 Mg)

Justoza S 5/50 Tablet 10 is primarily used for managing type 2 diabetes in adults. It is a combination medicine that falls under the category of antidiabetic medications.

This medicine also improves blood sugar control when used as part of a comprehensive treatment plan encompassing diet and exercise. Sometimes, it may be prescribed along with other antidiabetic medications based on individual treatment needs.

Before starting this medication, it's crucial to consult your doctor about the appropriate dosage and frequency. Make sure to inform your doctor about any preexisting health conditions or ongoing medications. If you notice any side effects while using this medicine, report them to your doctor immediately. Remember to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Justoza S 5/50 Tablet 10 is used for the following:

Management of type 2 diabetes in adults
Enhancing the action of insulin in adults with type 2 diabetes
Helping to lower blood sugar levels in adults with type 2 diabetes
Reducing the release of glucagon, a hormone that raises blood sugar levels, in adults with type 2 diabetes
Greater control of blood sugar levels when used as part of a comprehensive diabetes treatment plan

Directions for Use of Justoza S 5/50 Tablet 10

Swallow one tablet whole with a glass of water.
You can take this medicine with or without food as per your comfort.
Do not crush or chew the tablet.
Never exceed the recommended dose without consulting your doctor.
If you wish to stop taking this medicine, discuss it with your doctor first.

Justoza S 5/50 Tablet 10 is taken orally.

Side Effects of Justoza S 5/50 Tablet 10

Justoza S 5/50 Tablet 10 may cause the following side effects:

Low blood sugar
Headache
Upper respiratory tract infection (an infection that affects your nose, throat, and sinuses)
Stuffy or runny nose
Sore throat
Osteoarthritis: This condition causes inflammation and pain in your joints, particularly the knees, hips, and hands.
Arm or leg pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Justoza S 5/50 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of suggestions for managing common side effects:

Low Blood Sugar: Eat a small snack that includes both carbohydrates and protein, such as a piece of fruit with peanut butter, to quickly raise your blood sugar levels.
Headache: Rest in a quiet, dark room and stay hydrated by drinking water,

Justoza S 5/50 Tablet 10 is composed of two active ingredients:

Dapagliflozin (5 mg): This ingredient belongs to a class of medicines known as sodium/glucose cotransporter 2 (SGLT2) inhibitors. Its function is to block the reabsorption of glucose in your kidneys, leading to an increase in glucose excretion through urine. This helps lower blood sugar levels.
Sitagliptin (50 mg): Classified as a dipeptidyl peptidase-4 (DPP4) inhibitor, sitagliptin slows down the inactivation of incretin hormones that are released after meals. This action results in increased insulin secretion from the pancreas and decreased release of glucagon, a hormone that raises blood sugar levels. The combined effect helps improve blood sugar control.

Pregnancy

Justoza S 5/50 Tablet 10 is not recommended during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding women are advised not to use Justoza S 5/50 Tablet 10. Make sure to consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol when taking Justoza S 5/50 Tablet 10. Excessive alcohol consumption could increase the risk of low blood sugar levels. It's best to discuss this with your doctor.

Liver

If you have liver problems, make sure to discuss them with your doctor before starting Justoza S 5/50 Tablet 10. This medicine may affect liver function.

Kidney

If you have a history of kidney problems, exercise caution before using Justoza S 5/50 Tablet 10. Consult your doctor before taking this medicine.

Using Machines & Driving

No known adverse effects on driving or operating machinery have been reported. However, if you experience side effects like dizziness or low blood sugar, avoid driving or operating heavy machinery until you feel well again.

Allergy

If you're allergic to Dapagliflozin, Sitagliptin, or any other ingredients in Justoza S 5/50 Tablet 10, avoid taking this medicine. An allergic reaction may lead to skin rashes or difficulty breathing.

Children

Justoza S 5/50 Tablet 10 is not recommended for use in children and adolescents under 18 years of age due to insufficient safety and efficacy data.

Older Patients

Older patients should take Justoza S 5/50 Tablet 10 under medical supervision as they may be more susceptible to its side effects, particularly regarding kidney function. Your doctor will guide you based on your health status.

Interactions of Justoza S 5/50 Tablet 10

Drug-Drug Interactions

Justoza S 5/50 Tablet 10 interacts with the following medicines:

Insulin and Other Anti-Diabetic Medications: When taken together with Justoza S 5/50 Tablet 10, medicines like insulin or metformin can increase the risk of low blood sugar (hypoglycaemia).
Diuretics: Diuretic medicines such as hydrochlorothiazide or furosemide, when taken with Justoza S 5/50 Tablet 10, may lead to an increased risk of dehydration and kidney problems.
Non-Steroidal Anti Inflammatory Drugs (NSAIDs): If you take NSAIDs like ibuprofen or naproxen with Justoza S 5/50 Tablet 10, it could increase the chance of kidney problems.

Drug-Food Interactions

There are no known specific food interactions with Justoza S 5/50 Tablet 10.

Drug-Disease Interactions

Justoza S 5/50 Tablet 10 interacts with the following diseases:

Renal Impairment: If you have severe renal impairment or end-stage renal disease, using Justoza S 5/50 Tablet 10 may not be suitable as it can worsen your condition.
Geriatric Diseases: Elderly patients may be more sensitive to this medicine due to age-related decline in kidney function. Careful monitoring is required.

Daily Dose

The recommended daily dose of Justoza S 5/50 Tablet 10 should be taken as instructed by your doctor. This dosage might vary, depending on factors like how severe your condition is and how you respond to the medicine. It's vital to stick to the prescribed dosage and not to exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Justoza S 5/50 Tablet 10, you might experience symptoms like headaches, a stuffy or runny nose, or pain in your arms or legs. If these symptoms persist, inform your doctor.

Missed Dose

If you forget to take your Justoza S 5/50 Tablet 10 at the usual time, take it as soon as you remember. But if it's nearly time for your next dose, skip the one you missed and carry on with your regular schedule. Don't increase your dose without asking your doctor.

Store Justoza S 5/50 Tablet 10 at room temperature below 30°C.
Avoid exposure to extreme heat, light, and moisture.
Always keep the medicine secured and out of reach of children.
Ensure to use this medication before its expiry date.

Include fibre-rich foods in your diet. Foods like whole grains, fruits, and vegetables can help manage your blood sugar levels.
Regular physical exercise is important. A simple daily walk or light workout can help control type 2 diabetes. Always consult with your doctor before starting any new exercise regimen.

Fact Box

Drug Category	SGLT2 Inhibitor, DPP4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is Justoza S 5/50 Tablet 10 used for?

Justoza S 5/50 Tablet 10 is used to manage type 2 diabetes in adults, alongside a healthy diet and regular exercise.

How does Justoza S 5/50 Tablet 10 work?

This medicine works by blocking glucose reabsorption in the kidneys and enhancing insulin secretion from the pancreas, thus helping control blood sugar levels.

Can I take Justoza S 5/50 Tablet 10 during pregnancy or while breastfeeding?

No, it's not recommended to take Justoza S 5/50 Tablet 10 during pregnancy or while breastfeeding. Always consult your doctor before use.

Can children and teenagers take Justoza S 5/50 Tablet 10?

Justoza S 5/50 Tablet 10 is not recommended for use in individuals under 18 years old, as its safety and effectiveness are not established for this age group.

Are there any common side effects of Justoza S 5/50 Tablet 10?

Yes, some common side effects include low blood sugar, headache, upper respiratory tract infection, stuffy or runny nose, sore throat, osteoarthritis, and arm or leg pain.

What should I do if I experience severe side effects of Justoza S 5/50 Tablet 10?

If you experience severe side effects such as severe allergic reactions or persistent stomach pain, stop taking the medication and seek immediate medical attention.

Are there any lifestyle changes I should make while taking Justoza S 5/50 Tablet 10?

Yes, adopting a healthy diet, exercising regularly, maintaining a healthy body weight, quitting smoking and limiting alcohol can help manage type 2 diabetes effectively alongside medication.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Merck Sharp & Dohme Corp. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf
Sitagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01261

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