Inapure 25 Mg Tablet 10

Inapure 2.5 MG Tablet 10

Sun Pharma Laboratories Ltd.

Pack of 10 Units

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MRP ~~₹153~~

₹125.46

₹15.30/Units

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Composition

Ivabradine (2.5 Mg)

Strength:

5 MG 7.5 MG 2.5 MG

Inapure 2.5 Tablet is used to manage chronic angina, a type of chest pain caused by reduced blood flow to the heart. This medicine is part of a group of medicines known as hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers.

In addition to managing angina, this medicine is also used to manage chronic heart failure in patients with reduced left ventricular function. In both these conditions, it helps to improve the efficiency of the heart and reduces the risk of worsening symptoms that may require hospitalisation.

Before starting this medicine, it's important to consult your doctor for the appropriate dosage and frequency. You should inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, it is crucial to notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Inapure 2.5 Tablet is used for the following:

Management of chronic angina pectoris: This medicine helps in the control of persistent chest pain due to reduced blood flow to the heart.
Improvement in chronic heart failure: Inapure 2.5 Tablet is beneficial in managing persistent heart failure, specifically where there is a reduction in left ventricular function.

Directions for Use of Inapure 2.5 MG Tablet 10

Here's how you should take Inapure 2.5 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Never exceed the prescribed dose without consulting your doctor.
If you decide to stop taking this medicine, consult your doctor first.

Inapure 2.5 Tablet is taken orally.

Side Effects of Inapure 2.5 MG Tablet 10

Inapure 2.5 Tablet may have the following common side effects:

Dizziness
Headache
Visual disturbances: You might see bright spots or coloured lights that aren't actually there.
Bradycardia: This is the medical term for a slower than usual heart rate.
Fatigue
Nausea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Inapure 2.5 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dizziness: If dizziness occurs, consider taking Inapure 2.5 Tablet at bedtime.
Nausea: Try taking Inapure 2.5 Tablet with food or milk to lessen this effect.

The active ingredient in Inapure 2.5 Tablet is Ivabradine (2.5 mg), which works on the body as follows:

HCN Channel Blocking: Ivabradine works by selectively inhibiting certain channels in the heart's pacemaker cells called hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. These channels play a crucial role in controlling the heart rate.
Heart Rate Reduction: By blocking HCN channels, Ivabradine effectively slows down the heart rate. This reduced heart rate decreases the oxygen demand of the heart muscle, thereby increasing its efficiency. This action helps manage symptoms of both angina and heart failure.

Pregnancy

Caution is advised while taking Inapure 2.5 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is recommended to discuss with your doctor before starting Inapure 2.5 Tablet.

Alcohol

It's sensible to limit alcohol consumption while on Inapure 2.5 Tablet, as alcohol may impact heart health and the medicine's effectiveness.

Liver

Inapure 2.5 Tablet is contraindicated in severe liver disease. If you have mild to moderate liver impairment, consult your doctor before starting this medication.

Kidney

It’s advisable to consult your doctor before using Inapure 2.5 Tablet if you have any kidney health issues.

Using Machines & Driving

Inapure 2.5 Tablet can cause visual disturbances, so caution is advised when driving or operating machinery until you know how the medicine affects you.

Allergy

Let your doctor know if you have any allergies to Ivabradine or other medications before starting Inapure 2.5 Tablet.

Children

Inapure 2.5 Tablet is not intended for use in children under the age of 18 years. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients should take Inapure 2.5 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age due to potential liver and kidney issues.

Interactions of Inapure 2.5 MG Tablet 10

Drug-Drug Interactions

Inapure 2.5 Tablet interacts with the following medicines:

Antifungals: Medicines such as ketoconazole may interact with Inapure 2.5 Tablet, potentially increasing the risk of side effects.
Antibiotics: Medicines like rifampicin can affect how Inapure 2.5 Tablet works in your body.
QT-prolonging medications: If you're taking medicines like quinidine, disopyramide, or sotalol, they may interact with Inapure 2.5 Tablet and increase the risk of an irregular heartbeat.
Calcium channel blockers: Taking verapamil or diltiazem alongside Inapure 2.5 Tablet could alter the medicinal effects or increase the risk of side effects.

Drug-Food Interactions

Certain foods can interfere with how Inapure 2.5 Tablet works:

Grapefruit: Consuming grapefruit or its juice while taking Inapure 2.5 Tablet may increase the risk of side effects.

Drug-Disease Interactions

Inapure 2.5 Tablet interacts with the following diseases:

Severe Hypotension: If you have low blood pressure, you should be cautious while taking this medication as it could lower your blood pressure further.
Acute Heart Failure: Patients suffering from acute heart failure should avoid this medicine as it might worsen their condition.
Severe Hepatic Impairment: People with severe liver disease need to be careful as this medicine might exacerbate their condition.

Daily Dose

It's important to take the daily dose of Inapure 2.5 Tablet as prescribed by your doctor. The dosage could vary depending on individual factors like how severe your condition is and how well you respond to the medicine. Always follow your doctor's instructions and don't exceed the prescribed dosage without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Inapure 2.5 Tablet, you might experience some common side effects like dizziness, headache, and fatigue more intensely. If these symptoms persist or get worse, inform your doctor.

Missed Dose

If you forget to take your dose of Inapure 2.5 Tablet, take it as soon as you remember. But if it's nearly time for the next dose, skip the one you missed and go back to your normal schedule. Never increase your dosage without consulting your doctor.

Keep Inapure 2.5 Tablet in its original packaging to protect it from air and light.
Store it at room temperature.
Make sure this medicine is out of reach of children.
Always check the expiry date before using Inapure 2.5 Tablet.

If you're taking Inapure 2.5 Tablet for chronic angina or heart failure, try to include heart-healthy foods in your diet. This includes fish rich in omega-3 fatty acids, fruits, vegetables, and whole grains.
Regular physical activity can also help manage these conditions. However, don't overdo it. Start with light exercises like walking or cycling, and gradually increase the intensity as advised by your doctor.

Fact Box

Drug Category	HCN Channel Blocker
Therapeutic Category	Cardiovascular Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Angina, Heart Failure

What is the purpose of taking Inapure 2.5 Tablet?

It is used to manage chronic heart conditions like angina, which is chest pain, and heart failure.

How does Inapure 2.5 Tablet work in the body?

The medicine works by slowing down your heart rate, reducing the heart's oxygen demand and improving its efficiency.

Can I have grapefruit juice while taking Inapure 2.5 Tablet?

Avoid grapefruit juice when on this medication as it may increase the risk of side effects.

What should I do if I miss a dose of Inapure 2.5 Tablet?

Take it as soon as you remember but skip if it's close to your next dose time. Never double dose.

Can I drive while taking Inapure 2.5 Tablet?

As this medicine may cause visual disturbances, avoid driving until you know how it affects you.

How long before Inapure 2.5 Tablet starts working?

This varies between individuals; some might see improvement in days, others might take weeks.

Can I stop taking Inapure 2.5 Tablet if I feel better?

No, don't stop without consulting your doctor as this could worsen your condition.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Amgen. (2015). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209964lbl.pdf
VA Pharmacy Benefits Management Services, Medical Advisory Panel, and VISN Pharmacist Executives. (2015). Ivabradine Drug Monograph. https://www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/Ivabradine_CORLANOR_Monograph.pdf
Ivabradine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09083
Fala, L. (2016, March 1). Corlanor (Ivabradine), First HCN Channel Blocker, FDA Approved for the Treatment of Patients with Heart Failure. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013853/
Tse, S., & Mazzola, N. (2015, December 1). Ivabradine (Corlanor) for heart failure: the first selective and specific if inhibitor. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671466/

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