Hybreed H 20125 Mg Tablet 10

Hybreed H 20/12.5mg Tablet 10

East West Pharma

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Composition

Hydrochlorothiazide (12.5 Mg) + Olmesartan Medoxomil (20 Mg)

Hybreed H 20/12.5mg Tablet 10 is primarily used to manage hypertension or high blood pressure. This medication is a combination medicine and falls under the category of antihypertensive agents.

It also reduces the risk of serious cardiovascular events such as strokes and heart attacks by effectively controlling high blood pressure. It's particularly useful for patients who need multiple medications to manage their blood pressure levels.

Inform your doctor about any ongoing medications or pre-existing conditions. If you notice any side effects while taking this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Hybreed H 20/12.5mg Tablet 10 is beneficial for the following health conditions:

Management of high blood pressure or hypertension.
Used as a part of combination therapy for better control of high blood pressure.
Reducing the risk factors associated with fatal and non-fatal cardiovascular events, such as strokes and heart attacks.

Directions for Use of Hybreed H 20/12.5mg Tablet 10

Swallow the tablet whole with plenty of water. Do not crush or chew it.
It can be taken with or without food.
Avoid taking more than the recommended dose without consulting your doctor first.
Do not stop taking this medicine without discussing it with your doctor.

Hybreed H 20/12.5mg Tablet 10 is taken orally.

Side Effects of Hybreed H 20/12.5mg Tablet 10

Hybreed H 20/12.5mg Tablet 10 may cause the following common side effects:

Dizziness
Headache
Nausea
Fatigue
Muscle weakness
Electrolyte imbalances

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Hybreed H 20/12.5mg Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Hybreed H 20/12.5mg Tablet 10 with food or milk to help reduce this side effect.
Dizziness: Consider taking this medicine at night if it causes you dizziness during the day.

How Hybreed H 20/12.5mg Tablet 10 Works?

Hybreed H 20/12.5mg Tablet 10 consists of two main ingredients:

Hydrochlorothiazide (12.5 mg): This diuretic helps your body eliminate excess salt and water through urine. By doing so, it reduces the volume of fluid in your blood vessels, thereby helping lower blood pressure.
Olmesartan Medoxomil (20 mg): As an angiotensin II receptor blocker (ARB), Olmesartan Medoxomil works by blocking a substance called angiotensin II from binding to receptors in your blood vessel walls. Angiotensin II can cause blood vessels to narrow. So, by blocking its effects, olmesartan medoxomil allows your blood vessels to widen and relax, which further helps reduce blood pressure.

Pregnancy

Hybreed H 20/12.5mg Tablet 10 may cause harm to the foetus when taken by pregnant women. As soon as pregnancy is detected, this medication should be discontinued. It's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

This medication is not recommended during breastfeeding. If you are a nursing mother, ensure to consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol during the course of this medicine. It's best to consult your doctor for further guidance.

Liver

If you have liver diseases like cirrhosis, it's advisable to use Hybreed H 20/12.5mg Tablet 10 with caution. Do discuss your liver-related health concerns with your doctor before starting this medicine.

Kidney

Caution is advised for those with impaired kidney function while taking Hybreed H 20/12.5mg Tablet 10. If you have any history of kidney problems, consult your doctor before starting this medication.

Using Machines & Driving

Hybreed H 20/12.5mg Tablet 10 may cause dizziness or fatigue, which could possibly affect your ability to drive or operate machinery. If you experience these symptoms while taking this medicine, be cautious and avoid such activities.

Allergy

If you are allergic to any component of Hybreed H 20/12.5mg Tablet 10, it should be avoided. An allergic reaction may include symptoms like rash, itching, swelling, severe dizziness, and trouble breathing.

Children

This medicine is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medication to children.

Older Patients

If you are an older patient, take Hybreed H 20/12.5mg Tablet 10 under medical supervision as you might be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Hybreed H 20/12.5mg Tablet 10

Drug-Drug Interactions

Hybreed H 20/12.5mg Tablet 10 interacts with the following medicines:

Diuretics: If you take medicines such as furosemide or bumetanide alongside Hybreed H 20/12.5mg Tablet 10, it can lead to severe dehydration and possible kidney problems.
Potassium Supplements and Salt Substitutes: Using these together with Hybreed H 20/12.5mg Tablet 10 could result in high potassium levels in your blood, a condition known as hyperkalemia.
Bile Acid Sequestrants: Medicines like cholestyramine and colestipol may reduce the effectiveness of Hybreed H 20/12.5mg Tablet 10. To prevent this, take Hybreed H 20/12.5mg Tablet 10 at least 4 hours before or 4-6 hours after these medications.
Non-Steroidal Anti-Inflammatory Medicines (NSAIDs): Taking NSAIDs like ibuprofen or naproxen with an Hybreed H 20/12.5mg Tablet 10 may decrease the tablet's blood pressure-lowering effect.

Drug-Food Interactions

None

Drug-Disease Interactions

Hybreed H 20/12.5mg Tablet 10 interacts with the following diseases:

Kidney Disease: If you have impaired kidney function, use Hybreed H 20/12.5mg Tablet 10 cautiously, as it might further affect your kidney function.
Liver Disease: For those with liver diseases such as cirrhosis, using Hybreed H 20/12.5mg Tablet 10 needs careful monitoring as it could exacerbate your condition.
Anuria: People who cannot produce urine should not take Hybreed H 20/12.5mg Tablet 10 as it can lead to severe complications.

Daily Dose

The daily dose of Hybreed H 20/12.5mg Tablet 10 should be taken as prescribed by your doctor, who will consider individual factors like the severity of your condition and how you respond to the medication. Don't exceed this dosage without consulting your doctor. Please refer to the package insert for further details.

Over Dose

If an overdose happens, you might experience symptoms similar to the common side effects, such as dizziness, headache, and nausea in more severe form. If these symptoms persist or worsen, it's crucial to inform your doctor.

Missed Dose

If you happen to miss a dose of Hybreed H 20/12.5mg Tablet 10, take it as soon as you recall. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Increasing your dosage without consulting your doctor is not advisable.

Store Hybreed H 20/12.5mg Tablet 10 at room temperature, ideally between 20°C to 25°C.
Keep it in a tightly closed container to protect it from light and moisture.
Place the medicine out of reach of children for safety reasons.

Lower your salt intake as it can help manage high blood pressure, which Hybreed H 20/12.5mg Tablet 10 is used to control.
Regular physical exercise is beneficial in controlling hypertension. Aim for moderate-intensity exercises like brisk walking or cycling at least five days a week. Always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	Thiazide Diuretic, Angiotensin II Receptor Blocker
Therapeutic Category	Antihypertensives
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension

What is Hybreed H 20/12.5mg Tablet 10 used for?

Hybreed H 20/12.5mg Tablet 10 is used to manage hypertension or high blood pressure, reducing the risk of cardiovascular issues such as strokes and heart attacks.

How does Hybreed H 20/12.5mg Tablet 10 work?

It contains two ingredients: hydrochlorothiazide, a diuretic that reduces fluid volume in blood vessels, and olmesartan medoxomil, which relaxes and widens blood vessels.

Can I take Hybreed H 20/12.5mg Tablet 10 with food?

Yes, you can take Hybreed H 20/12.5mg Tablet 10 with or without food. It should be swallowed whole with a sufficient amount of fluid.

What are the possible side effects of Hybreed H 20/12.5mg Tablet 10?

Common side effects include dizziness, headache, nausea, fatigue, and muscle weakness. Serious yet rare side effects include allergic reactions and kidney failure.

Can pregnant women take Hybreed H 20/12.5mg Tablet 10?

No, this medicine may cause harm to the foetus, so it should be discontinued as soon as pregnancy is detected. It's not recommended during breastfeeding, either.

Are there any precautions I need to consider while taking Hybreed H 20/12.5mg Tablet 10?

Use with caution if you have impaired kidney function or liver diseases. Regular monitoring of your kidney function and serum electrolytes is advised.

How should I store my Hybreed H 20/12.5mg Tablet 10?

Store at room temperature between 20°C to 25°C in a tightly closed container, protected from light and moisture. Keep out of children's reach.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

1(1) ERRABALU (CHETTY STREET) MANNADY, VOC NAGAR CHENNAI Chennai - 600001 Tamil Nadu - India

Country of origin: INDIA

References

Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
Hydrochlorothiazide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682571.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3639, Hydrochlorothiazide. Retrieved June 18, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Hydrochlorothiazide
Olmesartan: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00275
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 130881, Olmesartan Medoxomil. Retrieved June 18, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Olmesartan-Medoxomil

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