Headon Injection 1

Headon Injection is utilised for the following purposes:

• Management of acromegaly, a hormonal disorder caused by excess growth hormone

• Control of severe diarrhoea and flushing in carcinoid syndrome

• Alleviating symptoms of VIPomas

• In certain diagnostic procedures to assess growth hormone reserve and pituitary function

Administer Headon Injection as recommended below:

• The medication comes as a powder and needs to be prepared with sterile water before use.

• It's administered via a subcutaneous or intravenous injection.

• Ensure to rotate the injection sites to avoid skin changes.

• Always consult your doctor for specific instructions about how and when to administer this medicine.

Headon Injection is administered subcutaneously or intravenously.

Headon Injection is a combination medicine that contains several components:

• Somatostatin (4 IU): This active ingredient interacts with multiple receptors in your body, inhibiting the release of growth hormone from the pituitary gland, suppressing insulin and glucagon secretion from the pancreas, reducing gastric acid secretion and intestinal motility, and modulating neurotransmission in the central nervous system.

• Mannitol (22 ml): It helps to increase blood volume and reduce blood viscosity, which aids in the treatment of growth hormone deficiency by promoting diuresis and reducing intracranial pressure.

• Glycine (2 ml): It helps maintain the stability and shelf life of the injection by preventing the growth of microorganisms and ensuring the proper pH balance.

• Disodium Hydrogen Phosphate Dodecahydrate (2.58 ml): It helps to regulate the pH of the injection, ensuring that it remains within a safe and effective range for use in the body.

• Sodium Dihydrogen Phosphate Monohydrate (0.39 ml): It helps to regulate the pH of the injection, ensuring that it remains within a safe and effective range for use in the body.

These combined actions help control symptoms and complications associated with acromegaly and neuroendocrine tumours.

• Keep Headon Injection in a cool place, ideally between 2-8°C, which means it should be refrigerated.

• Protect it from exposure to light.

• Remember to keep it out of reach and sight of children.

• If you're managing acromegaly with Headon Injection, maintain a balanced diet rich in calcium and vitamin D to support bone health, as this condition can increase your risk of osteoporosis.

• For those using Headon Injection for carcinoid syndrome or VIPomas, a low-fat diet can help manage diarrhoea symptoms. Consider foods like rice, bananas, and applesauce.