Greatum 750 Mg Injection 1

Greatum 750 Injection 1

Zydus Healthcare Ltd

Vial of 1 Units

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MRP ~~₹310~~

₹154.69

₹310.00/Units

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Composition

Cefuroxime (750 Mg)

Greatum 750 Injection 1 is primarily used to manage a variety of bacterial infections. This medicine belongs to a class of medications known as second-generation cephalosporin antibiotics.

Apart from its main use, it also manages infections in various parts of the body, such as the lower respiratory tract, including pneumonia, urinary tract, skin and skin structures, septicemia (blood infection), meningitis, gonorrhoea, and bone and joint infections. It can also be used as a preventive measure against infections during certain surgical procedures.

Before beginning this medicine, it's crucial to consult your doctor about any pre-existing conditions or any ongoing medicines. If you notice any unusual effects while on this medication, inform your doctor immediately. To achieve the best results, continue taking the medication for the full duration prescribed by your doctor.

Greatum 750 Injection 1 is used for the following:

Managing lower respiratory tract infections, including pneumonia
Addressing urinary tract infections
Coping with skin and skin structure infections
Controlling septicemia, a blood infection
Handling meningitis, an inflammation of the protective membranes of the brain and spinal cord
Dealing with gonorrhoea, a sexually transmitted infection
Assisting with bone and joint infections
Preventing infections in certain surgical procedures

Directions for Use of Greatum 750 Injection 1

Administer Greatum 750 Injection 1 in the following way:

The injection should be administered by a healthcare professional only.
It is administered either as an intravenous infusion or as an intramuscular injection.
Reconstituted solution should be used within 5 hours if stored at room temperature.
For any further information or specific advice, please consult your doctor.

Greatum 750 Injection 1 is administered intravenously or via an intramuscular route.

Greatum 750 Injection 1 may have the following common side effects:

Pain, swelling or inflammation at the injection site
Nausea
Vomiting
Diarrhoea
Transient elevation of liver enzymes
Allergic reactions like rash, itching (pruritus), hives (urticaria), fever
Eosinophilia: This is where the body produces more eosinophils (a type of white blood cell) than usual.
Leucopenia: This refers to a decrease in the number of white blood cells in your blood.
Neutropenia: This is a condition where the number of neutrophils (a type of white blood cell) in your blood is lower than normal.
Thrombocytopenia: This condition involves a decrease in platelets, which are cells that help your blood to clot.

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Greatum 750 Injection 1. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Vomiting: If you experience vomiting after getting Greatum 750 Injection 1, try having it with meals to lessen these effects.
Pain at the injection site: If this discomfort persists or worsens even after applying a cold compress, speak to your doctor.

Greatum 750 Injection 1 contains Cefuroxime (750 MG), which works on your body in the following ways:

Bacterial Cell Wall Inhibition: Cefuroxime inhibits the synthesis of bacterial cell walls by inactivating penicillin-binding proteins (PBPs) that are situated on the inner membrane of the cell wall. This stops the cross-linkage of peptidoglycan chains, which are needed for bacterial cell wall strength and rigidity.
Induction of Cell Lysis: The inhibition of the bacterial cell wall leads to its weakening and causes cell lysis i.e., disintegration or rupture of the cell wall, leading to the death of bacteria.
Stability Against Beta-lactamases: A distinctive feature of cefuroxime is its stability against certain beta-lactamases produced by bacteria, which would typically inactivate many penicillins and cephalosporins.

Pregnancy

If you're expecting, exercise caution when considering Greatum 750 Injection 1. Consult your doctor before starting this medication.

Breastfeeding

For nursing mothers, Greatum 750 Injection 1 may be used with caution. It's preferable to discuss this with your doctor to understand the potential risks and benefits.

Alcohol

It is advised not to consume alcohol if this injection is prescribed to you to avoid any adverse effects.

Liver

This medicine should be used cautiously if you have mild liver problems. It's not recommended for severe liver diseases. If you have liver health issues, discuss them with your doctor before beginning Greatum 750 Injection 1.

Kidney

If you have a history of kidney issues, it's advisable to use caution before administering Greatum 750 Injection 1. Consulting your doctor is a good idea before starting this medication.

Using Machines & Driving

If you feel unwell after the injection, avoid these activities and discuss it with your doctor.

Allergy

Greatum 750 Injection 1 is contraindicated if you're allergic to cefuroxime or other cephalosporins. If you've had allergic reactions to similar medications in the past, it's crucial to inform your doctor.

Children

Greatum 750 Injection 1 should be given to children under 18 years of age only under medical supervision. Always consult your doctor before giving this medication to a child.

Older Patients

Older patients should use Greatum 750 Injection 1 under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Greatum 750 Injection 1 interacts with the following medicines:

Uricosurics: Medicines like probenecid used for gout can increase and prolong serum concentrations of cefuroxime, the active ingredient in Greatum 750 Injection 1.
Oral Anticoagulants: Blood thinners such as warfarin may have enhanced effects when used with Greatum 750 Injection 1. This might require monitoring of prothrombin time.

Drug-Food Interactions

There are no specific known food interactions with Greatum 750 Injection 1. However, it's always a good idea to take it at a fixed time for better efficiency.

Drug-Disease Interactions

Greatum 750 Injection 1 interacts with the following diseases:

Kidney Disease: In patients with renal impairment, the dosage of Greatum 750 Injection 1 should be adjusted as it is excreted unchanged by the kidneys.
Allergies: Patients allergic to penicillins or cephalosporins should use Greatum 750 Injection 1 cautiously, due to possible cross-reactivity between these classes of antibiotics.

Daily Dose

The recommended dose of Greatum 750 Injection 1 should be administered as instructed by your doctor. The dosage may vary depending on individual aspects, such as the condition's severity and your response to the medicine. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

An overdose of this injection is unlikely as it is administered by a healthcare professional. In the event of an overdose, you may experience common side effects like nausea, vomiting, diarrhoea, or skin rashes. If these symptoms persist or worsen, you should let your doctor know right away.

Missed Dose

If you forgot to get Greatum 750 Injection 1 as scheduled, do so as soon as you can. But if it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Avoid increasing your dosage without your doctor's advice.

Keep Greatum 750 Injection 1 in a cool, dry place.
Protect the medicine from light and moisture.
Ensure this medication is out of reach of children.

If you're managing a urinary tract infection with Greatum 750 Injection 1, increase your water intake. This helps flush out bacteria from your system more effectively.
For those using this medicine to manage skin infections, maintain good skin hygiene. Regularly cleanse your skin with mild soap to prevent further bacterial growth.

Fact Box

Drug Category	Bactericidal Agent
Therapeutic Category	Antibiotic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Pneumonia, Urinary Tract Infections, Meningitis

What is Greatum 750 Injection 1 used for?

Greatum 750 Injection 1 is used to manage a variety of bacterial infections, including respiratory, urinary tract, skin and bone infections, and septicemia.

How does Greatum 750 Injection 1 work?

Greatum 750 Injection 1 kills bacteria by blocking the synthesis of their cell wall. This weakens the bacteria, causing them to burst and die.

Can I administer Greatum 750 Injection 1 myself?

It is strongly suggested that Greatum 750 Injection 1 must be administered exclusively by a healthcare professional within a clinical setting.

What are the side effects of Greatum 750 Injection 1?

Common side effects include pain at the injection site, gastrointestinal disturbances like nausea, elevated liver enzymes, allergic reactions, and headaches.

Who should not use Greatum 750 Injection 1?

You should avoid Greatum 750 Injection 1 if you're allergic to cefuroxime or other cephalosporins. It’s also advised for those with penicillin allergy to use caution.

Can I use Greatum 750 Injection 1 while pregnant or breastfeeding?

Use of this medicine during pregnancy or while breastfeeding should only be when clearly needed. Consult your doctor for advice.

How should I store my Greatum 750 Injection 1?

Protect it from light. Once mixed, the solution is stable for up to two days when refrigerated.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

References

Cefuroxime: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01112
Cefuroxime injection: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a684044.html
Omole, A. E., Awosika, A. O., & Patel, P. (2024, January 11). Cefuroxime. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK599503/
PubChem. (n.d.-a). Cefuroxime. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Cephuroxime
DailyMed - CEFUROXIME SODIUM injection, powder, for solution. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6290bcdd-b093-40fd-81f9-81f8e79dcf7b

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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