Gluvilda D 10mg 100mg Tablet

Gluvilda D 10 Tablet 10

Alkem Laboratories Ltd.

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Composition

Dapagliflozin (10 Mg) + Vildagliptin (100 Mg)

Gluvilda D10 Tablet is primarily used to manage type 2 diabetes mellitus. It's a combination medication, part of a group of medicines known as oral antidiabetic agents.

In addition to its main use, this medicine can further enhance glycaemic control in adults when both of its active ingredients are deemed beneficial for treatment. This makes it particularly useful in regulating blood sugar levels in adults suffering from diabetes type 2.

Before you start on this medicine, it's crucial to consult your doctor about the correct dosage and frequency based on your condition. Remember to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Gluvilda D10 Tablet is used for the following:

Improving blood sugar levels in adults with type 2 diabetes mellitus
Helping to manage high blood sugar when diet and exercise alone are insufficient
Serving as an adjunct to diet and exercise for better glycemic control in type 2 diabetes patients
Providing a dual-action approach to blood sugar management where both dapagliflozin and vildagliptin are deemed appropriate by the doctor

Directions for Use of Gluvilda D 10 Tablet 10

Here's how you should take Gluvilda D10 Tablet:

Thoroughly follow the dosage and timing guidelines provided by your doctor for taking this medicine.
Do not change or exceed the prescribed dose without consulting your doctor.
Avoid discontinuing this medication without your doctor's advice. Always consult your doctor before stopping.
Adhere to the diet plan recommended by your doctor.

Gluvilda D10 Tablet is taken orally.

Gluvilda D10 Tablet may have the following common side effects:

Genital mycotic infections: These include infections by yeast or fungi in the genital area.
Urinary tract infections
Nasopharyngitis: This is inflammation of the nasopharynx, the area behind your nose and above the back of your throat.
Headache
Nausea
Diarrhoea
Upper respiratory tract infections
Back pain
Arthralgia: This refers to joint pain, which can occur in any part of your body where two or more bones meet.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gluvilda D10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: If you experience nausea, consult your doctor for advice on how to manage this side effect. Stick to the diet recommended by your doctor.
Diarrhoea: Consume plenty of fluids to avoid dehydration.

Gluvilda D10 Tablet contains two key active ingredients that work together:

Dapagliflozin (10 mg): This is classified as a sodium-glucose cotransporter-2 (SGLT2) inhibitor. It works by blocking the reabsorption of glucose in the kidneys. This leads to more glucose being excreted in the urine and consequently lower blood sugar levels.
Vildagliptin (100 mg): As a dipeptidyl peptidase-4 (DPP-4) inhibitor, this medicine helps increase the levels of certain hormones called incretins (like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)). These hormones stimulate insulin secretion and reduce glucagon secretion in a glucose-dependent manner, helping to regulate blood sugar levels even better.

These two ingredients work in tandem to manage type 2 diabetes mellitus effectively.

Pregnancy

Caution is advised while taking Gluvilda D10 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding women should exercise caution when taking Gluvilda D10 Tablet. Discuss this with your doctor to understand the potential risks and benefits.

Alcohol

It is advisable to limit alcohol consumption while on this medication and discuss any concerns with your doctor.

Liver

It is advisable to discuss liver-related concerns with your doctor before starting treatment with Gluvilda D10 Tablet. They will evaluate if this medicine is suitable.

Kidney

Gluvilda D10 Tablet is contraindicated in cases of severe kidney impairment. If you have a history of kidney problems, make sure to discuss them with your doctor before starting this medication.

Using Machines & Driving

Gluvilda D10 Tablet does not affect your ability to drive or operate machinery. However, consult your doctor before taking up any heavy work.

Allergy

If you've ever had a serious allergic reaction to dapagliflozin or vildagliptin, or any other ingredients in Gluvilda D10 Tablet, avoid taking it. Always inform your doctor about your past allergic reactions.

Children

Caution is advised while giving Gluvilda D10 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Gluvilda D10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gluvilda D10 Tablet interacts with the following medicines:

Insulin and Insulin Secretagogues: When used with Gluvilda D10 Tablet, medicines like insulin or gliclazide can increase the risk of low blood sugar or hypoglycemia. A lower dose may be required to prevent this.
Renal Impairment Medicines: In patients with moderate renal impairment, certain medicines may require a dose adjustment when taken with Gluvilda D10 Tablet.

Drug-Food Interactions

There are no specific food items that interact with Gluvilda D10 Tablet. However, maintaining a balanced diet is essential for managing type 2 diabetes.

Drug-Disease Interactions

Gluvilda D10 Tablet interacts with the following diseases:

Renal Impairment: The medicine is contraindicated in severe renal impairment or end-stage renal disease. Persons with moderate renal impairment should adjust their dosage.
Hypersensitivity: Patients allergic to dapagliflozin, vildagliptin, or other tablet components should avoid taking Gluvilda D10 Tablet.
Pancreatitis: If you have a history of pancreatitis, caution is advised as acute pancreatitis has been reported in patients taking vildagliptin.
Ketoacidosis: There have been rare cases of ketoacidosis in patients using SGLT2 inhibitors like dapagliflozin. If suspected, discontinue use and seek immediate medical attention.

Daily Dose

The daily dose of Gluvilda D10 Tablet should be taken as instructed by your doctor. The dosage may be adjusted based on factors such as the severity of your condition and how you respond to the medication. Always adhere to the dosage prescribed by your doctor and avoid exceeding it without a consultation.

Over Dose

An overdose of Gluvilda D10 Tablet may lead to symptoms such as nausea, dizziness, and a headache. In case you take an extra dose by mistake, don't panic but inform your doctor about it.

Missed Dose

If you forget to take a dose of Gluvilda D10 Tablet, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Gluvilda D10 Tablet at room temperature, ideally between 15°C and 30°C.
Keep the medicine in a dry place, away from excessive moisture.
Avoid exposure to direct sunlight or extreme heat.
Always keep the medicine out of reach of children.
Make sure to use the medicine before its expiry date.

As you manage your type 2 diabetes with Gluvilda D10 Tablet, it's crucial to maintain a diet low in sugar and carbohydrates. This can help keep your blood glucose levels stable.
Regular physical activity is also beneficial. Try to incorporate some form of exercise into your daily routine, such as brisk walking or cycling.

Fact Box

Drug Category	SGLT2 Inhibitor, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Gluvilda D10 Tablet used for?

Gluvilda D10 Tablet is used to manage type 2 diabetes mellitus, along with diet and exercise, to improve blood sugar control.

How does Gluvilda D10 Tablet work?

This medicine combines two active ingredients, dapagliflozin and vildagliptin, which work together to lower blood sugar levels by increasing urine glucose excretion and stimulating insulin secretion.

Can Gluvilda D10 Tablet be taken anytime during the day?

Thoroughly follow the dosage and timing guidelines provided by your doctor for taking this medicine.

Are there any side effects of Gluvilda D10 Tablet?

Possible side effects include urinary tract infections, headaches, nausea, back pain, joint pain and genital yeast infections. More severe side effects may also occur.

Can I take Gluvilda D10 Tablet if I have kidney problems?

If you have severe kidney impairment or end-stage renal disease, this medicine is not recommended. Consult your doctor for alternatives.

Will taking Gluvilda D10 Tablet affect my urine glucose test results?

Yes, dapagliflozin in the medicine increases urinary glucose excretion which might lead to positive urine glucose tests.

How should I store Gluvilda D10 Tablet?

Store the medicine at room temperature between 15°C and 30°C. Protect it from moisture and keep it out of children's reach.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
NVR & FB. (2020). Galvus. In Galvus (pp. 1–19). https://www.novartis.com/sg-en/sites/novartis_sg/files/Galvus-Jul2020.SIN-App051120.pdf
Vildagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04876
Joshi, A., Birla, A., Prasad, A., & Warrier, S. (2022). Bioequivalence study of a fixed-dose combination of Dapagliflozin/ Vildagliptin Sustained Release tablets in healthy adult male subjects: A Randomized, Open-Label, Crossover Study. Journal of Drug Delivery and Therapeutics, 12(6), 105–109. https://doi.org/10.22270/jddt.v12i6.5798

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