Gluconorm G 1 Tablet Er 15

Gluconorm G1 Tablet 15

Lupin Ltd

Strip of 15 Units

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MRP ~~₹225.3~~

₹184.75

₹15.02/Units

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Composition

Glimepiride (1 Mg) + Metformin (500 Mg)

Gluconorm G1 Tablet is primarily used to manage type 2 diabetes mellitus. This medicine is a combination of two active components, falling under the classes of sulfonylureas and biguanides.

Besides its primary use, this tablet can also effectively control blood sugar levels better than using metformin alone. Lowering blood glucose levels is essential in managing diabetes and decreasing the risk of complications such as heart disease, kidney damage, and nerve problems.

Your doctor will determine your dosage based on your blood sugar levels and your response to treatment. Always consult your doctor about pre-existing conditions or ongoing medications before beginning this medicine. If you notice any side effects while taking this medication, inform your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Gluconorm G1 Tablet is used for the following:

Managing type 2 diabetes mellitus: This medicine is used when diet and exercise don't provide adequate blood sugar control.
Supplementing single-agent therapy: It's used when either glimepiride or metformin alone doesn't sufficiently control blood glucose levels.
Reducing the risk of diabetes complications: Lowering blood glucose levels can help manage diabetes and lower the likelihood of issues such as cardiovascular disease, kidney damage, and nerve problems.

Directions for Use of Gluconorm G1 Tablet 15

Here's how to take Gluconorm G1 Tablet properly:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always take your medication with food to lower the risk of stomach upset.
The tablet should be taken at the same time each day for the best results.
Continue taking this medicine even if you feel well; stopping without consulting your doctor can lead to increased blood sugar levels and potential complications.

Gluconorm G1 Tablet is taken orally.

Gluconorm G1 Tablet may have the following common side effects:

Hypoglycaemia
Stomach pain and Diarrhoea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gluconorm G1 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycaemia: Keep some glucose tablets or fruit juice handy. They can quickly boost your blood sugar levels if they drop too low.
Stomach pain and diarrhoea: Try taking Gluconorm G1 Tablet with food to minimise these effects.

Gluconorm G1 Tablet is a combination medication that includes two active ingredients:

Metformin Hydrochloride (500 mg): Classified as a biguanide, metformin works by reducing the amount of glucose produced by the liver and improving body cell sensitivity to insulin.
Glimepiride (1 mg): As part of the sulfonylurea class, glimepiride stimulates the pancreas to produce more insulin, a hormone that regulates blood sugar levels. It also enhances the sensitivity of body cells to insulin, thus facilitating more effective absorption of glucose from the bloodstream.
These ingredients work together synergistically to decrease blood sugar levels effectively.

Pregnancy

Gluconorm G1 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding women should be careful while taking Gluconorm G1 Tablet. Consult your doctor to understand the potential risks and benefits.

Alcohol

Alcohol consumption can interfere with the effectiveness of Gluconorm G1 Tablet. It's advisable to limit or avoid alcohol while taking this medication.

Liver

Caution is advised while taking Gluconorm G1 Tablet in case of mild to moderate liver impairment. It's not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine. This medication may affect liver function.

Kidney

Gluconorm G1 Tablet should not be taken if you have severe kidney disease, and caution is advised if you have a history of any kidney problems. Ensure you consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause side effects such as dizziness or confusion. If you experience these, it's best not to drive or operate heavy machinery until the symptoms subside.

Allergy

If you are allergic to glimepiride or metformin, you shouldn't take the Gluconorm G1 Tablet. Inform your doctor about any known allergies before starting this medication.

Children

Gluconorm G1 Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Gluconorm G1 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gluconorm G1 Tablet interacts with the following medicines:

Beta-blockers: If you're taking medicines like atenolol or propranolol, they may affect blood sugar levels when used with the Gluconorm G1 Tablet.
Thiazide Diuretics: Taking diuretics such as hydrochlorothiazide with Gluconorm G1 Tablet can affect your blood sugar control.

Drug-Food Interactions

Specific known food interactions aren't documented for this medication.

Drug-Disease Interactions

Gluconorm G1 Tablet interacts with the following diseases:

Severe Liver Disease: The same is true if you have severe liver disease; this medicine could exacerbate your condition.
Type 1 Diabetes Mellitus: Gluconorm G1 Tablet isn't recommended if you have type 1 diabetes.

Daily Dose

You should take the daily dose of Gluconorm G1 Tablet as prescribed by your doctor. The dosage may vary, depending on your condition and how you respond to the medicine. Always stick to the prescribed dosage and never exceed it without your doctor's advice.

Over Dose

In case of an overdose, common symptoms can include nausea, abdominal discomfort, and frequent urination. If you believe you have exceeded your prescribed dosage, inform your doctor.

Missed Dose

If you've forgotten to take your Gluconorm G1 Tablet at the scheduled time, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Don't increase your dosage without consulting your doctor.

Keep your Gluconorm G1 Tablet at a temperature below 30°C.
Store it in a dry place, avoiding exposure to direct sunlight and moisture.
Always keep this medicine out of the reach of children.

Regular physical activity is beneficial. Strive for at least 30 minutes of moderate-intensity exercise, such as brisk walking, every day to assist in managing your type 2 diabetes.
Follow a balanced diet that's low in sugar and rich in whole grains, fruits, and vegetables to help regulate your blood sugar levels.

Fact Box

Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is the Gluconorm G1 Tablet used for?

Gluconorm G1 Tablet is prescribed for managing type 2 diabetes when diet and exercise alone aren't enough. It's not intended for type 1 diabetes.

How does the Gluconorm G1 Tablet work in the body?

This medicine reduces your blood sugar levels by increasing insulin production and sensitivity, and decreasing liver glucose production. Both actions help manage diabetes effectively.

Can the Gluconorm G1 Tablet be taken during pregnancy?

If you're pregnant or planning a pregnancy, consult your doctor before taking this medicine; its safety during pregnancy hasn't been established yet.

What should I do if I forget to take my Gluconorm G1 Tablet dose?

Take the missed dose as soon as you remember, unless it's almost time for your next one. Then continue with your regular schedule. Don't double up doses.

What should I do if I experience hypoglycaemia symptoms?

If you feel lightheaded, confused, or shaky, eat fast-acting carbohydrates like glucose tablets or fruit juice immediately. If symptoms persist or worsen, seek medical help promptly.

Are there any known drug interactions with Gluconorm G1 Tablet?

Yes, Gluconorm G1 Tablet may interact with other medications including beta-blockers, corticosteroids, thiazide diuretics, and thyroid hormones which can affect blood sugar levels. Always inform your doctor about all the medications you are taking.

What should I do if I experience symptoms of lactic acidosis while taking a Gluconorm G1 Tablet?

If you experience symptoms of lactic acidosis, such as rapid or deep breathing, persistent nausea, vomiting, and stomach pain, seek immediate medical attention.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

National Health Service. (n.d.). Glimepiride. https://www.nhs.uk/medicines/glimepiride/how-and-when-to-take-glimepiride/. Accessed 1 April 2024.
U.S. National Library of Medicine. (n.d.). Glimepiride Tablet. DailyMed. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a Accessed 1 April 2024.
Novo Nordisk Canada Inc. (2019). PRODUCT MONOGRAPH. In GlucoNorm® (Repaglinide Tablets) 0.5 Mg, 1 Mg and 2 Mg [Report]. https://www.novonordisk.ca/content/dam/nncorp/ca/en/products/gluconorm-product-monograph-english1.pdf
LaMoia, T. E., & Shulman, G. I. (2021). Cellular and Molecular Mechanisms of Metformin Action. Endocrine reviews, 42(1), 77–96. https://doi.org/10.1210/endrev/bnaa023
Galani, V., & Vyas, M. (2010). In vivo and In vitro Drug Interactions Study of Glimepride with Atorvastatin and Rosuvastatin. Journal of young pharmacists : JYP, 2(2), 196–200. https://doi.org/10.4103/0975-1483.63169

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