Glidum Mf 4 1000 Sr Tablet 10

Glidum Mf 4/1000 Sr Tablet 10

Knoll Healthcare Pvt. Ltd.

Strip of 10 Units

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MRP ~~₹115~~

₹57.39

₹11.50/Units

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Composition

Glimepiride (4 Mg) + Metformin (1000 Mg)

Glidum Mf 4/1000 Sr Tablet 10 is a medication primarily used to manage type 2 diabetes mellitus in adults. It is a combination medicine that falls under the category of oral antidiabetic medications.

This medicine is prescribed when dietary regulations, exercise, and treatment with a single agent aren't sufficient to control blood glucose levels. It is also indicated in patients already being treated with both glimepiride and metformin as separate tablets.

You should take this medication as directed by your doctor. Before starting this medicine, it is important to inform your doctor about any pre-existing conditions or ongoing medications. If any severe side effects are noticed while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Glidum Mf 4/1000 Sr Tablet 10 is used for the following:

Management of type 2 diabetes mellitus in adults.
Enhancing glycaemic control when diet and exercise fail to show desired results.
Improving blood sugar levels when single agent therapy is insufficient.
Switching from separate tablets of Glimepiride and Metformin to a combined tablet formulation.

Directions for Use of Glidum Mf 4/1000 Sr Tablet 10

Here's how you should take Glidum Mf 4/1000 Sr Tablet 10:

The tablet should be swallowed whole with a glass of water.
Do not chew, crush or cut the tablet.
Always take this medicine with meals to minimise any potential gastrointestinal side effects.
Regularly monitor your blood glucose levels while taking this medicine.
Consult your doctor for any specific advice related to the use of this medication.

Glidum Mf 4/1000 Sr Tablet 10 is taken orally.

Side Effects of Glidum Mf 4/1000 Sr Tablet 10

Glidum Mf 4/1000 Sr Tablet 10 may have the following side effects:

Hypoglycaemia
Diarrhoea
Nausea and vomiting

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Glidum Mf 4/1000 Sr Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Glidum Mf 4/1000 Sr Tablet 10 with food to lessen this effect.
Hypoglycaemia: If low blood sugar occurs after taking this medicine, consider having a small snack ready to consume promptly.

How Glidum Mf 4/1000 Sr Tablet 10 Works?

Glidum Mf 4/1000 Sr Tablet 10 combines two active ingredients:

Glimepiride (4 mg): This belongs to a class of medications called sulfonylureas. Glimepiride works by stimulating the beta cells in the pancreas to secrete insulin. It also enhances the sensitivity of peripheral tissues to insulin, effectively assisting in lowering blood glucose levels.
Metformin (1000 mg): As a biguanide, metformin functions by reducing liver glucose production and decreasing intestinal glucose absorption. It also improves insulin sensitivity by increasing peripheral glucose uptake and utilisation.

Pregnancy

If you are pregnant, caution is advised when taking Glidum Mf 4/1000 Sr Tablet 10. It is recommended to consult your doctor before starting this medication as it should only be used if the potential benefits justify the risks to the unborn baby.

Breastfeeding

Metformin, one of the active ingredients in Glidum Mf 4/1000 Sr Tablet 10, is present in human milk and glimepiride may increase breast milk production. If you are breastfeeding, it is suggested to use an alternative treatment or discontinue nursing while taking this medication.

Alcohol

Alcohol can intensify the effect of metformin on lactate metabolism. Therefore, it is advisable to avoid excessive alcohol intake while taking Glidum Mf 4/1000 Sr Tablet 10.

Liver

If you have liver problems, be cautious when taking Glidum Mf 4/1000 Sr Tablet 10. This medicine is not recommended if you have severe liver dysfunction. Before starting this medication, discuss any liver-related concerns with your doctor.

Kidney

Glidum Mf 4/1000 Sr Tablet 10 is contraindicated in cases of severe kidney disease. Before starting this medicine, make sure your kidney function is assessed by your doctor, especially if you have a history of kidney issues.

Using Machines & Driving

No specific precautions are indicated for driving or operating machinery while taking Glidum Mf 4/1000 Sr Tablet 10. However, remember that low blood sugar or hypoglycemia can affect such activities.

Allergy

If you are allergic to glimepiride, metformin or any other ingredient present in Glidum Mf 4/1000 Sr Tablet 10, avoid using this medicine.

Children

Glidum Mf 4/1000 Sr Tablet 10 has not been established as safe and effective for use in children. Hence, it is advised to consult your doctor before giving this medication to any individual under 18 years of age.

Older Patients

Older patients should take Glidum Mf 4/1000 Sr Tablet 10 under medical supervision as they may be more susceptible to its side effects. Due to the greater likelihood of renal impairment, it is important to assess kidney function more frequently in elderly patients.

Interactions of Glidum Mf 4/1000 Sr Tablet 10

Drug-Drug Interactions

Glidum Mf 4/1000 Sr Tablet 10 interacts with the following medicines:

Cationic medicines: Medicines like amiloride, digoxin, and morphine may increase the risk of metformin accumulating in your body, leading to a condition called lactic acidosis.
Alcohol: Intake of alcohol can increase metformin's effect on lactate metabolism, which could potentially lead to lactic acidosis.
Hyperglycemic medicines: Certain medications, such as thiazides diuretics, corticosteroids and oral contraceptives can increase blood sugar levels and may reduce the effectiveness of Glidum Mf 4/1000 Sr Tablet 10.

Drug-Food Interactions

Glidum Mf 4/1000 Sr Tablet 10 interacts with certain foods:

High-fat meals: Consuming high-fat meals may delay the absorption of glimepiride from your stomach into your bloodstream, thus reducing its effectiveness in controlling blood sugar levels.

Drug-Disease Interactions

Glidum Mf 4/1000 Sr Tablet 10 interacts with the following diseases:

Kidney disease: If you have severe kidney disease, there is a risk that metformin might build up in your body, which could lead to lactic acidosis.
Congestive heart failure: If you have chronic heart problems that require medication, Glimepiride and Metformin could potentially worsen your condition.
Liver disease: If you have severe liver impairment, it could potentially exacerbate your condition by increasing the risk of lactic acidosis.

Daily Dose

The daily dose of Glidum Mf 4/1000 Sr Tablet 10 should be as per your doctor's prescription. The dosage may vary depending on the severity of your condition and your response to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, read the package insert.

Over Dose

Overdosing on Glidum Mf 4/1000 Sr Tablet 10 can lead to common side effects such as hypoglycaemia (low blood sugar), nausea, vomiting, and abdominal pain. If you have taken more than the prescribed dose, inform your doctor about it.

Missed Dose

If you forget to take Glidum Mf 4/1000 Sr Tablet 10 at the scheduled time, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust the dosage without consulting with your doctor.

Store Glidum Mf 4/1000 Sr Tablet 10 in a dry and dark place.
The ideal storage temperature is between 10°C and 25°C.
Keep the medicine away from direct sunlight and moisture.
Always keep Glidum Mf 4/1000 Sr Tablet 10 out of reach of children.
Make sure to use the medicine before its expiration date.

To help manage your type 2 diabetes, maintain a balanced diet rich in fibre, but low in fat and sugar. This can assist in controlling your blood sugar levels effectively.
Regular physical activity is crucial. Aim for at least 150 minutes of moderate-intensity exercise, such as brisk walking or cycling, every week.

Fact Box

Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is Glidum Mf 4/1000 Sr Tablet 10 used for?

Glidum Mf 4/1000 Sr Tablet 10 is used to manage type 2 diabetes in adults when diet, exercise, and single-agent therapy don't adequately control blood sugar levels.

How does Glidum Mf 4/1000 Sr Tablet 10 work?

Glidum Mf 4/1000 Sr Tablet 10 works by combining glimepiride, which stimulates insulin secretion, and metformin, which decreases glucose production and absorption. These medications together help lower blood sugar levels.

Can I crush or chew Glidum Mf 4/1000 Sr Tablet 10?

No, you should swallow the tablet whole. Crushing or chewing it can impact the sustained release of the active ingredients.

Are there any side effects of Glidum Mf 4/1000 Sr Tablet 10?

Yes, common side effects include hypoglycaemia (low blood sugar), diarrhoea, nausea/vomiting, abdominal pain, headache, and upper respiratory infection.

Can I drink alcohol while taking Glidum Mf 4/1000 Sr Tablet 10?

You should avoid excessive alcohol intake while taking this medicine, as it can increase the risk of lactic acidosis - a potentially dangerous build-up of lactic acid in your blood.

Is Glidum Mf 4/1000 Sr Tablet 10 safe to take during pregnancy?

The safety of Glidum Mf 4/1000 Sr Tablet 10 during pregnancy isn't fully established. If you are pregnant or planning to be, consult your doctor before taking this medicine.

What should I do if I miss a dose of Glidum Mf 4/1000 Sr Tablet 10?

If you miss a dose of Glidum Mf 4/1000 Sr Tablet 10, take it as soon as you remember. However, if it is close to your next dose time, skip the missed dose and continue your regular schedule.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

M17, Pharma Tower,, Phase-1, Badli Industrial Area,, Badli, Delhi, 110042

Country of origin: INDIA

References

DailyMed. (n.d.). GLIMEPIRIDE tablet [Teva Pharmaceuticals USA Inc]. DailyMed. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=1200ea71-8a9e-4e49-bb77-7d9fe0d84ae7
U.S. Food and Drug Administration. (2011, August 12). Approval letter - Metformin hydrochloride; Glimepiride. U.S. Food and Drug Administration. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2011/021071s038,021410s026,021700s010ltr.pdf
U.S. Food and Drug Administration. (2006, October 31). Label - Metformin hydrochloride; Glimepiride. U.S. Food and Drug Administration. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
Glimepiride. (n.d.). Retrieved 18 June 2024, from https://go.drugbank.com/drugs/DB00222
Metformin. (n.d.). Retrieved 18 June 2024, from https://go.drugbank.com/drugs/DB00331

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