Erlonat 150 Mg Tablet 30

Erlonat 150 Tablet 30

Natco Pharma Ltd

Strip of 30 Units

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Composition

Erlotinib (150 Mg)

Strength:

150 MG 100 MG

Erlonat 150 Tablet 30 is primarily used to manage advanced nonsmall cell lung cancer (NSCLC) and pancreatic cancer. This medicine falls under the category of medications known as kinase inhibitors.

It is also used in managing locally advanced or metastatic NSCLC and pancreatic cancer. It proves particularly effective for patients whose tumours possess certain mutations in the epidermal growth factor receptor (EGFR).

You should take this medication as advised by your doctor. It's crucial to inform your doctor about any existing health conditions or ongoing medications before starting this medicine. In case you experience any side effects, let your doctor know right away. To achieve the best results, it's important to continue with the medication for the duration prescribed by your doctor.

Erlonat 150 Tablet 30 is used for the following:

Managing advanced nonsmall cell lung cancer: This medicine helps to manage a specific type of lung cancer that has spread locally or to other parts of the body.
First line therapy for metastatic nonsmall cell lung cancer: It is used as an initial treatment for this condition, especially when the tumours have certain mutations in the epidermal growth factor receptor (EGFR).
Managing pancreatic cancer that has spread: This medicine is used in combination with another medication called gemcitabine to manage pancreatic cancer that can't be removed by surgery or has spread to other parts of the body.

Directions for Use of Erlonat 150 Tablet 30

Here's how you should take Erlonat 150 Tablet 30:

Swallow the tablet whole with a glass of water. Do not chew or crush it.
Administer this medicine on an empty stomach, at least one hour before or two hours after your meals.
Do not take more than recommended by your doctor without consulting them first.
If you need to stop taking this medicine, do so only after discussing with your doctor.

Erlonat 150 Tablet 30 is taken orally.

Erlonat 150 Tablet 30 may cause the following common side effects:

Rash
Diarrhoea
Loss of appetite and weight loss
Fatigue
Cough
Nausea and vomiting
Mouth sores: These are painful ulcers or blisters that appear in your mouth.
Eye irritation or inflammation: This can make your eyes feel sore, red, or swollen.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Erlonat 150 Tablet 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a few tips to manage some common side effects:

Diarrhoea: Try taking Erlonat 150 Tablet 30 on an empty stomach (at least one hour before or two hours after a meal).
Nausea and vomiting: Consider taking this medicine at night to minimise these symptoms during the day.

Erlonat 150 Tablet 30 contains erlotinib (150 mg). This component works in two key ways:

Inhibits epidermal growth factor receptor (EGFR) tyrosine kinase: Erlotinib functions by blocking a protein called EGFR tyrosine kinase found on the surface of cancer cells. This protein plays a significant role in the growth and spread of these cells.
Slows cancer progression: By inhibiting EGFR, erlotinib effectively slows down or halts the progression of cancer, thereby managing the condition.

Pregnancy

Erlonat 150 Tablet 30 can cause harm to the foetus. If you are pregnant or planning to conceive, it is important to discuss this with your doctor before starting this medicine.

Breastfeeding

Erlonat 150 Tablet 30 is not recommended for breastfeeding women. Speak to your doctor about the potential risks and benefits before taking this medicine.

Alcohol

Caution is advised while consuming alcohol with Erlonat 150 Tablet 30.

Liver

If you have preexisting liver problems, caution is advised when taking Erlonat 150 Tablet 30. This medicine may affect liver function, so discuss your health status with your doctor before starting treatment.

Kidney

If you have any kidney issues, it's wise to consult your doctor before using Erlonat 150 Tablet 30. This medicine may have an impact on kidney function.

Using Machines & Driving

Since Erlonat 150 Tablet 30 may cause fatigue or vision changes, be careful when driving or operating machinery. It's best to understand how this medicine affects you before engaging in such activities.

Allergy

Erlonat 150 Tablet 30 should not be taken if you're allergic to erlotinib or any of the other ingredients in the tablet. If you have any known allergies, discuss them with your doctor beforehand.

Children

Erlonat 150 Tablet 30 is not suitable for children under 18 years of age. If a child needs this type of medication, always consult a doctor first.

Older Patients

Older patients should use Erlonat 150 Tablet 30 only under medical supervision as they may be more susceptible to its side effects. They might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Antacids, H2 receptor antagonists, and Proton pump inhibitors (PPIs): Medicines such as ranitidine, omeprazole, or pantoprazole can reduce the absorption of Erlotinib in your body.
CYP3A4 inhibitors: Medications like ketoconazole, itraconazole, and clarithromycin can increase the levels of Erlotinib in your body.
CYP3A4 inducers: Medicines like rifampin, phenytoin, and carbamazepine can decrease the levels of Erlotinib in your body.
Anticoagulants: The effect of blood thinners like warfarin may be increased when used alongside Erlotinib.

Drug-Food Interactions

Grapefruit and its juice: These can increase the risk of side effects from Erlonat 150 Tablet 30.

Drug-Disease Interactions

Gastrointestinal conditions: Patients with a history of peptic ulcer disease or diverticular disease are at an increased risk of perforation when on Erlonat 150 Tablet 30.
Respiratory conditions: Patients with a history of respiratory conditions such as interstitial pneumonitis or pulmonary fibrosis may become worsened when taking this medication.
Liver disease: If you have a preexisting liver condition, you should exercise caution as Erlonat 150 Tablet 30 could worsen your condition.
Kidney disease: People with kidney problems should also be cautious as Erlonat 150 Tablet 30 could exacerbate their condition.

Daily Dose

The daily dose of Erlonat 150 Tablet 30 should be taken as recommended by your doctor. This dosage may vary based on individual factors like the severity of your condition and how you respond to the medicine. Always adhere to the dosage prescribed by your doctor and avoid exceeding it without consulting them. For further details regarding dosage, please read the package insert.

Over Dose

Overdosing on Erlonat 150 Tablet 30 can lead to common side effects becoming more pronounced. If you recognise these symptoms worsening or persisting for an extended time, inform your doctor.

Missed Dose

If you forget to take Erlonat 150 Tablet 30 as directed, take it as soon as you remember. However, if it's almost time for your next dose, then skip the missed one and continue with your regular schedule. Don't increase your dosage without consulting with your doctor.

Store Erlonat 150 Tablet 30 at a room temperature of 15 to 30 °C.
Keep the container tightly sealed to protect the medicine from light and moisture.
Always store this medicine in a secure place, out of the reach of children.
Check the expiration date on the packaging and ensure you use the medicine before it expires.

If you're undergoing treatment for nonsmall cell lung cancer or pancreatic cancer with Erlonat 150 Tablet 30, avoid smoking. Smoking can reduce the effectiveness of this medicine in managing your condition.
Also, try to avoid grapefruit and grapefruit juice. These can increase your risk of side effects from Erlonat 150 Tablet 30.

Fact Box

Drug Category	Kinase Inhibitor
Therapeutic Category	Anticancer
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Non small Cell Lung Cancer, Pancreatic Cancer

What is the main use of Erlonat 150 Tablet 30?

Erlonat 150 Tablet 30 is primarily used to manage advanced non-small cell lung cancer and pancreatic cancer.

How does Erlonat 150 Tablet 30 work in my body?

Erlonat 150 Tablet 30 works by inhibiting a protein called EGFR on cancer cells, slowing or stopping their growth and spread.

Can I take Erlonat 150 Tablet 30 with food?

No, Erlonat 150 Tablet 30 should be taken on an empty stomach, either one hour before or two hours after a meal.

Are there any serious side effects of Erlonat 150 Tablet 30?

Yes, severe diarrhoea, skin reactions, breathing difficulties, vision changes, and signs of liver or kidney problems require immediate medical attention.

How can I manage the side effects of Erlonat 150 Tablet 30?

Simple changes like using mild soaps for rashes or drinking lots of fluids for diarrhoea can help manage side effects. Consult your doctor for more advice.

Is it safe to smoke while taking Erlonat 150 Tablet 30?

No, smoking should be avoided, as it can reduce the effectiveness of this medicine.

Can Erlonat 150 Tablet 30 interact with other medications I am taking?

Yes, Erlonat 150 Tablet 30 can interact with various medications like antacids, anticoagulants, and others. Always inform your doctor about all medicines you are currently taking.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

Natco House Road No.2, Banjara Hills Hyderabad-500 034, India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2016). Erlotinib (Tarceva) Label. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021743s025lbl.pdf
Carter, J., & Tadi, P. (2022, December 21). Erlotinib. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK554484/
Erlotinib: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00530
Wang, Y., Schmid-Bindert, G., & Zhou, C. (2011). Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians. Therapeutic Advances in Medical Oncology, 4(1), 19–29. https://doi.org/10.1177/1758834011427927

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