Epidosin 8 Mg Injection 20 Ml

Epidosin 8 MG Injection 20 ML

Ttk Healthcare Ltd

AMPOULE of 1 ML
Pack of 20 ML

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MRP ~~₹617.1~~

₹506.02

₹30.86/ML

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Composition

Valethamate (8 Mg)

Epidosin Injection is primarily used to manage the discomfort associated with smooth muscle spasms. This medicine belongs to a class of medications known as anticholinergic and spasmolytic agents.

In addition to managing pain from smooth muscle spasms, this is also used for conditions such as dysmenorrhoea (painful menstruation), post-operative pain, intestinal spasms, and spasms of the urinary tract and bile duct. It also aids in cervical dilation during labour.

Consult your doctor for the right dosage and frequency for you. It's important that you inform your doctor about any current health conditions or ongoing medications before starting this medicine. Should you notice any side effects, make sure to inform your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Epidosin Injection is used for managing the following health conditions:

Dysmenorrhoea, which is painful menstruation
Post-operative pain and intestinal spasms, often experienced after surgery
Spasms of the urinary tract and bile duct, also known as renal or biliary colic
Cervical dilation during labour, aiding in childbirth

Directions for Use of Epidosin 8 MG Injection 20 ML

Administer Epidosin Injection in the following manner:

This medicine should only be administered by a healthcare professional.
It's important to ensure that Epidosin Injection is not self-administered at home.
The injection process usually happens in a hospital or clinic setting.
The medicine is given either intramuscularly or as a slow intravenous injection.
For specific advice on how to use this medicine, always consult your doctor.

Epidosin Injection is administered intramuscularly or via slow intravenous injection.

Side Effects of Epidosin 8 MG Injection 20 ML

Epidosin Injection might have the following common side effects:

Drowsiness
Nausea and vomiting

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Epidosin Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Drowsiness: Consider having an Epidosin Injection administered at night if it makes you drowsy during the day.
Nausea and vomiting: If these occur after the injection, try to eat a light snack before your next dose.

How Epidosin 8 MG Injection 20 ML Works?

Epidosin Injection contains valethamate (8 mg). The activity of this medicine is as follows:

Anticholinergic Action: Valethamate bromide works by inhibiting the action of acetylcholine - a chemical messenger responsible for contraction of smooth muscles. By blocking acetylcholine, it reduces the contractions of these muscles.
Spasmolytic Action: Valethamate helps in relieving spasms and associated pain in organs composed of smooth muscles such as intestines, cervix, urinary tract and bile duct. This relaxation leads to pain relief in conditions like dysmenorrhoea and renal colic.
Cervical Dilation: During labour, valethamate aids in cervical dilation thereby facilitating childbirth.

Pregnancy

Caution is advised while being administered Epidosin Injection if you're pregnant. It's best to consult your doctor before receiving this medicine.

Breastfeeding

Epidosin Injection is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Avoid alcohol consumption while taking this medicine as it can increase side effects such as drowsiness, dizziness, or blurred vision.

Liver

If you have mild to moderate liver issues, caution is advised when Epidosin Injection is administered. This medicine may affect liver function. Discuss these concerns with your doctor before starting this medication.

Kidney

Epidosin Injection should be used with caution if you have a history of kidney problems. Consulting your doctor before starting this medication is advisable.

Using Machines & Driving

Since Epidosin Injection can cause drowsiness and blurred vision, avoid driving or operating heavy machinery after its administration.

Allergy

If you are allergic to Valethamate or any other components present in Epidosin Injection, avoid its use. Discuss this with your doctor before administration.

Children

Epidosin Injection is meant for adult use. Always consult your doctor before giving any medicine to a child under 18 years of age.

Older Patients

Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status before administering Epidosin Injection.

Interactions of Epidosin 8 MG Injection 20 ML

Drug-Drug Interactions

Epidosin Injection interacts with the following medicines:

Antipsychotics: Concomitant use of antipsychotics like risperidone or olanzapine may increase the risk of anticholinergic side effects.
Antihistamines: Medicines such as cetirizine or loratadine may interact, potentially exacerbating symptoms like dry mouth and blurred vision.
Antispasmodics: When administered with antispasmodics like mebeverine and dicyclomine, Epidosin Injection may enhance the anticholinergic effects.
Tricyclic antidepressants: Co-administration with medicines like amitriptyline or imipramine could increase the anticholinergic effect.
MAO inhibitors: Interactions with medicines like phenelzine or tranylcypromine may increase the side effects of Epidosin Injection.
Opioid analgesics: Medicines like morphine or oxycodone may interact, potentially enhancing side effects such as constipation and urinary retention.

Drug-Food Interactions

No known specific food items have been reported to interact with Epidosin Injection.

Drug-Disease Interactions

Epidosin Injection interacts with the following diseases:

Severe liver or kidney dysfunction: This medicine might worsen the condition in patients suffering from severe liver or kidney disease.
Autonomic neuropathy: It should be used cautiously in patients with autonomic neuropathy due to a potential increase in side effects.
Hyperthyroidism: Patients diagnosed with hyperthyroidism may experience an exaggerated response to Epidosin Injection.
Coronary heart disease and Hypertension: Those diagnosed with these diseases should be cautious, as this medication can potentially increase heart rate.

Daily Dose

The daily dose of Epidosin Injection should be administered as directed by your doctor. The dosage may vary depending on your personal health conditions and how you respond to the medication. Always follow your doctor's instructions and never exceed the prescribed dosage.

Over Dose

If too much Epidosin Injection is administered, you might experience symptoms like severe dry mouth, blurred vision, and rapid heartbeat. If this happens, it's important to inform your doctor right away.

Missed Dose

If you happen to miss a dose of Epidosin Injection, receive it as soon as you remember. However, if it's nearly time for your next dose, let go of the missed one and continue with your regular dosage schedule. Always consult your doctor before making any changes to the dosage.

Store Epidosin Injection at room temperature, ideally between 15°C to 25°C.
Keep the medicine away from direct light and moisture.
Always keep this product out of reach of children.

If you're experiencing painful menstruation, try a diet rich in calcium and magnesium, like green leafy vegetables and nuts, which can help manage muscle spasms.
For individuals with urinary tract spasms, increase water intake to help dilute urine and potentially reduce discomfort. As always, consult your doctor for personalised advice.

Fact Box

Drug Category	Anticholinergic, Spasmolytic
Therapeutic Category	Antispasmodic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Dysmenorrhea, Renal/Biliary Colic, Cervical Dilation

What is Epidosin Injection used for?

Epidosin Injection is utilised for managing pain and spasms in smooth muscles, which occur in conditions such as menstrual cramps, renal/biliary colic, and during labour.

How does Epidosin work?

Epidosin contains valethamate bromide which blocks acetylcholine, a chemical that causes muscle contraction, thus helping to reduce spasms and pain by relaxing muscles.

Who administers Epidosin Injection?

Epidosin Injection should be administered by a doctor or nurse either into a muscle or into a vein; it is not meant for self-administration.

Can I take Epidosin Injection if I have kidney disease?

If you have severe kidney disease, you should avoid Epidosin Injection. Always consult your doctor before starting any new medication.

What are the possible side effects of Epidosin?

Possible side effects include dry mouth, blurred vision, rapid heartbeat, constipation and drowsiness. However, these are usually mild and temporary.

Can I drink alcohol while on Epidosin Injection?

It's best to avoid alcohol while using Epidosin Injection as it can intensify the side effects such as drowsiness and dizziness.

Is it safe to use Epidosin Injection during pregnancy?

The safety of Epidosin Injection during pregnancy has not been established. Thus, if you're pregnant, it's crucial to consult with your doctor before use.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

6, Cathedral Road Chennai – 600 086.

Country of origin: INDIA

References

VALETHEMATE BROMIDE AND CERVICAL DILATATION. (2017, June 26). NIH NLM. Retrieved May 23, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531893/
Valethamate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB13497
Fixed-Dose combination of NSAIDs and spasmolytic agents in the treatment of different types of Pain—A Practical Review. (2021). National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306558/
Sarbhjit, K., S K, B., Parmjit, K., & Surinder, B. (2013). To compare the effect of camylofin dihydrochloride (anafortin) with combination of valethamate bromide (epidosin) and hyoscine butyl-N-bormide (buscopan) on cervical dilation. Journal of clinical and diagnostic research : JCDR, 7(9), 1897–1899. https://doi.org/10.7860/JCDR/2013/6231.3345

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