Entavir 1 Mg Tablet 10

Entavir 1.0mg Tablet 10

Cipla Ltd.

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Composition

Entecavir (1 Mg)

Strength:

1 MG 0.5 MG

Entavir 1.0 mg Tablet is primarily used to manage chronic hepatitis B virus (HBV) infection in adults. It's part of the class of medicines known as nucleoside reverse transcriptase inhibitors (NRTIs).

Besides managing HBV, it's indicated for those showing active viral replication and increased levels of serum aminotransferases or histologically active disease. It serves as a first-line option for patients new to treatment and those resistant to lamivudine, another antiviral medicine.

Ensure you consult your doctor for the right dosage and frequency of use. Before starting on this medicine, let your doctor know of any pre-existing conditions or ongoing medications. If you experience any side effects, inform your doctor right away. To get the best results, continue taking it for the duration your doctor prescribes.

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Entavir 1.0 mg Tablet is used for the following:

Managing chronic hepatitis B virus (HBV) infection in adults: This medicine is particularly beneficial for individuals showing signs of active viral replication.
Reducing persistent elevations in serum aminotransferases: Serum aminotransferases are enzymes linked to liver health and disease.
Treating histologically active disease: Histologically active disease refers to conditions that are actively progressing and can be detected through tissue examination.
First-line treatment option for treatment-naïve patients: These are patients who have not previously received any treatment for their condition.
Use in patients resistant to lamivudine: Lamivudine is another antiviral medicine used to manage HBV. Entavir 1.0 mg Tablet is effective for those who have developed resistance to it.

Directions for Use of Entavir 1.0mg Tablet 10

Here's how you should take Entavir 1.0 mg Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
For specific advice on how to best use this medicine, it's important to consult your doctor.

Entavir 1.0 mg Tablet is taken orally.

Entavir 1.0 mg Tablet may have the following common side effects:

Headache
Fatigue
Dizziness
Nausea
Vomiting
Diarrhoea
Abdominal pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Entavir 1.0 mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Entavir 1.0 mg Tablet with food to lessen this effect.
Abdominal Pain: Taking this medicine after a meal can help manage stomach discomfort.

Entavir 1.0 mg Tablet contains entecavir (1 mg). Its mechanism of action is as follows:

Inhibits HBV Polymerase: Entecavir works by targeting HBV polymerase, an enzyme crucial for viral replication. By inhibiting this enzyme, the medicine helps control the spread of the virus.
DNA Chain Termination: After being activated within cells, entecavir competes with the natural substrate deoxyguanosine triphosphate and gets incorporated into viral DNA. This action leads to DNA chain termination, effectively halting HBV replication.

Pregnancy

Caution is advised while taking Entavir 1.0 mg Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you're breastfeeding, discuss the potential risks and benefits of using Entavir 1.0 mg Tablet with your doctor.

Alcohol

You should avoid alcohol consumption while taking Entavir 1.0 mg Tablet, as it can increase the risk of liver damage.

Liver

If you have any liver problems, it's essential to discuss them with your doctor before starting Entavir 1.0 mg Tablet. This medicine may affect liver function.

Kidney

Before using Entavir 1.0 mg Tablet, caution is advised if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There's no specific information on the effects of Entavir 1.0 mg Tablet on the ability to drive or operate machinery. Nevertheless, if you feel dizzy or sleepy after taking this medicine, avoid such activities until you feel alert again.

Allergy

Entavir 1.0 mg Tablet should not be taken if you have a known hypersensitivity to entecavir or any of the tablet's inactive ingredients.

Children

Entavir 1.0 mg Tablet is indicated for adults only; it is not recommended for use in children under 18 years of age.

Older Patients

Older patients should take Entavir 1.0 mg Tablet under medical supervision as they may be more susceptible to its side effects and might also have liver and kidney issues.

Drug-Drug Interactions

Entavir 1.0 mg Tablet interacts with the following medicines:

Medicines that affect kidney function: Medications such as diclofenac or indomethacin could potentially increase the serum concentrations of entecavir.
Medicines that compete for active tubular secretion: Medicines like tenofovir and adefovir may interact with Entavir 1.0 mg Tablet, increasing the blood concentration of either medicine.

Drug-Food Interactions

Drug-Disease Interactions

Entavir 1.0 mg Tablet interacts with the following diseases:

Kidney Disease: Patients with kidney problems should be cautious, as Entavir 1.0 mg Tablet can affect kidney function and may require dose adjustments.
Liver Disease: Individuals with liver problems might need close monitoring while using this medicine, as it can potentially impact liver health.

Daily Dose

The daily dose of Entavir 1.0 mg Tablet should be as advised by your doctor. The dosage can vary based on factors such as the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the recommended dose of Entavir 1.0 mg Tablet, you might experience symptoms such as headache, fatigue, or nausea. Avoid panicking and consult your doctor for advice on how to manage these symptoms.

Missed Dose

If you miss a dose of Entavir 1.0 mg Tablet, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one now and continue with your usual dosage schedule. Do not increase your dosage without consulting your doctor.

Keep Entavir 1.0 mg Tablet in its original packaging, preserving it from exposure to light and moisture.
The ideal storage temperature is below 30°C.
Ensure the medicine is stored away from the reach of children.
Always check the expiry date and use this medication before it expires.

Since Entavir 1.0 mg Tablet manages chronic hepatitis B infection, a diet low in fat and high in fruits, vegetables, and whole grains can support your liver health.
Avoid alcohol consumption while taking this medicine, as it can increase the risk of liver damage.

Fact Box

Drug Category	Nucleoside Reverse Transcriptase Inhibitor
Therapeutic Category	Antiviral
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Hepatitis B

What is the purpose of taking Entavir 1.0 mg Tablet?

Entavir 1.0 mg Tablet is taken to manage chronic Hepatitis B virus infection in adults.

How does Entavir 1.0 mg Tablet work inside my body?

This medicine works by decreasing the multiplication of the Hepatitis B virus in your body.

Can Entavir 1.0 mg Tablet completely eliminate Hepatitis B from my body?

While it can significantly decrease the multiplication of the virus, it cannot completely eliminate it.

Is it safe to consume alcohol while taking Entavir 1.0 mg Tablet?

It's best to avoid alcohol while taking this medication as it may increase the risk of liver damage.

Can pregnant women take Entavir 1.0 mg Tablet?

Pregnant women should consult their doctor about the potential risks and benefits before taking this medicine.

What should I do if I forget to take a dose of Entavir 1.0 mg Tablet?

If you miss a dose, take it as soon as possible unless it's close to your next dosage time.

Can I stop taking Entavir 1.0 mg Tablet when I feel better?

You should not discontinue this medicine without consulting your doctor, even if you feel better.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Bristol-Myers Squibb. (2005). BARACLUDE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021797s011lbl.pdf
NCATS Inxight Drugs — ENTECAVIR. (n.d.). https://drugs.ncats.io/drug/5968Y6H45M
Cani, E., Park, T. E., & Kavanagh, R. (2019). Antiviral drugs. In Side effects of drugs annual (pp. 301–319). https://doi.org/10.1016/bs.seda.2019.10.005
Lourenço, T., & Vale, N. (2023). Entecavir: A review and Considerations for its application in Oncology. Pharmaceuticals, 16(11), 1603. https://doi.org/10.3390/ph16111603
Entecavir: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00442
Entecavir: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a605028.html

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