E Klav 1000200 Mg Injection 1

E Klav 1.2gm Injection 1

Ekansh Pharma

Vial of 1 UNITS

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MRP ~~₹127~~

₹104.14

₹127.00/UNITS

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Composition

Amoxicillin (1000 Mg) + Clavulanic Acid (200 Mg)

E Klav 1.2gm Injection 1 is primarily used to manage moderate to severe bacterial infections. This combination medicine belongs to the class of antibiotics, specifically the penicillin type.

This injection can also manage a range of other bacterial infections. These include respiratory tract infections like pneumonia and bronchitis, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, septicaemia, bone and joint infections, and genital infections.

Before starting this medicine, it's important to consult your doctor about the appropriate dosage and frequency. Ensure you inform your doctor about any pre-existing conditions or ongoing medication you may be taking. Consult your doctor immediately if you observe any side effects while using this medicine. Lastly, it's crucial to continue taking the medicine for the duration prescribed by your doctor for optimal results.

E Klav 1.2gm Injection 1 is used for:

Managing respiratory tract infections, including pneumonia and bronchitis
Controlling urinary tract infections
Handling skin and soft tissue infections
Managing intra-abdominal infections
Addressing septicaemia, a serious blood infection
Dealing with bone and joint infections
Managing genital infections

Directions for Use of E Klav 1.2gm Injection 1

To administer E Klav 1.2gm Injection 1, follow these steps:

The injection is administered intravenously, directly into a vein or through an IV tube.
It should be administered by a healthcare professional only.
It's crucial to flush the IV line before and after each injection.

E Klav 1.2gm Injection 1 is administered intravenously.

Side Effects of E Klav 1.2gm Injection 1

E Klav 1.2gm Injection 1 may have the following common side effects:

Diarrhoea
Nausea
Skin rash
Urticaria (skin rash that can cause itchy, red welts)
Vomiting
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of E Klav 1.2gm Injection 1. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Stay hydrated with clear fluids and avoid spicy or fatty foods until symptoms improve.
Nausea: Eat small, frequent meals and avoid greasy or strong-smelling foods.

E Klav 1.2gm Injection 1 consists of two active components:

Amoxicillin (1000 mg): This semisynthetic penicillin-type antibiotic inhibits the formation of bacterial cell walls. It deactivates proteins inside the bacterial cell wall that build cross-links between peptidoglycan chains, which is necessary for the strength and rigidity of bacterial cell walls. As a result of this interference, the bacterial cell wall weakens, leading to cell destruction.
Clavulanic acid (200 mg): This component doesn't have significant antibacterial activity but plays a vital role in protecting amoxicillin from destruction by specific enzymes called beta-lactamases produced by certain bacteria. It extends the spectrum of amoxicillin’s activity to include many bacteria that are usually resistant to it and other similar antibiotics.

Pregnancy

Caution is advised while taking E Klav 1.2gm Injection 1 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

E Klav 1.2gm Injection 1 is cautiously used while breastfeeding as amoxicillin is excreted in breast milk. Please consult your doctor for advice.

Alcohol

Consuming alcohol can intensify certain side effects. It's better to avoid drinking alcohol if you are under any medication. Always consult your doctor regarding alcohol intake.

Liver

If you have liver problems, be cautious before starting E Klav 1.2gm Injection 1. This medicine may affect liver function, especially if you've had a history of jaundice or hepatic dysfunction related to amoxicillin.

Kidney

If you have kidney issues, it's advisable to consult your doctor before using E Klav 1.2gm Injection 1. Your dosage might need to be adjusted depending on your kidney function.

Using Machines & Driving

E Klav 1.2gm Injection 1 has no known effects that could affect your ability to drive or operate machinery.

Allergy

Avoid using E Klav 1.2gm Injection 1 if you're allergic to penicillin or cephalosporin antibiotics. If you've got allergies or asthma, use this medicine with caution.

Children

E Klav 1.2gm Injection 1 can be given to children under medical supervision. The dosage depends on the child's weight and the severity of the infection.

Older Patients

Older patients should take E Klav 1.2gm Injection 1 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of E Klav 1.2gm Injection 1

Drug-Drug Interactions

E Klav 1.2gm Injection 1 may interact with the following medicines:

Uric acid medications such as Probenecid: This medication reduces the kidney's secretion of amoxicillin, increasing its levels in the body. Only use them together if a doctor specifically recommends it.
Anticoagulants like warfarin: When taken together with E Klav 1.2gm Injection 1, may have enhanced effects. Regular monitoring of prothrombin times is crucial.
Metabolites such as Methotrexate: Amoxicillin can decrease the excretion of methotrexate, potentially leading to an increased risk of toxicity.
Xanthine oxidase inhibitors such as Allopurinol: The risk of developing a rash may increase when used with E Klav 1.2gm Injection 1.
Oral Contraceptives: E Klav 1.2gm Injection 1 may reduce the effectiveness of oral contraceptives such as ethinylestradiol. It's advisable to use additional contraception during treatment.

Drug-Food Interactions

There are no specific food interactions known with E Klav 1.2gm Injection 1.

Drug-Disease Interactions

E Klav 1.2gm Injection 1 can interact with the following diseases:

Liver Disease: Patients with liver disease should be cautious, as this medication could exacerbate their condition.
Renal Impairment: If you have kidney disease, your doctor may adjust your dose accordingly.
Mononucleosis: There is an increased risk of skin rashes in people with mononucleosis who take E Klav 1.2gm Injection 1.

Daily Dose

The recommended dose of this injection is determined by your doctor, who will consider factors like the severity of your condition and your response to the medicine. Always follow the prescribed dosage and refrain from exceeding it without consulting your doctor.

Over Dose

Overdose of this injection is unlikely as a healthcare professional administers it. The symptoms of overdose of this injection include nausea, skin rash or diarrhoea. If you suspect an overdose, inform your doctor.

Missed Dose

If you miss a dose of E Klav 1.2gm Injection 1, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and follow your regular dosage schedule. Avoid adjusting the dosage without consulting your doctor.

Store E Klav 1.2gm Injection 1 in the refrigerator or between 2°C to 8°C. Do not freeze.
Shield the product from light and avoid damp places.
Keep this medicine out of reach of children.
Always check the expiry date before administering the injection.

Increase your water intake if you're managing a urinary tract infection with E Klav 1.2gm Injection 1. This helps flush out bacteria from your system.
For respiratory tract infections like pneumonia or bronchitis, avoid smoking and exposure to second-hand smoke, as it can exacerbate your symptoms.

Fact Box

Drug Category	Antibiotics
Therapeutic Category	Antibacterial
Available Dosage Types	Injection
Habit Forming	No
Ailment	Pneumonia, Urinary tract infections, Septicaemia

What is E Klav 1.2gm Injection 1 used for?

This medicine manages severe bacterial infections, including respiratory, urinary tract, skin, intra-abdominal, bone and joint, and genital infections.

How does E Klav 1.2gm Injection 1 work?

It contains amoxicillin, which weakens the bacteria's cell walls, causing them to burst, and clavulanic acid, which prevents bacteria from becoming resistant to amoxicillin.

How is E Klav 1.2gm Injection 1 administered?

A healthcare professional administers this injection via intravenous injection or infusion. The dose depends on the severity and location of the infection.

Who shouldn't use E Klav 1.2gm Injection 1?

It shouldn't be used if you're hypersensitive to penicillin or have a history of liver dysfunction due to amoxicillin or penicillin. Consult your doctor for alternatives.

What are the common side effects of E Klav 1.2gm Injection 1?

Common side effects include diarrhoea, nausea, rash, vomiting, headache and urticaria (hives). If these continue or get worse, contact your doctor promptly.

Can I take E Klav 1.2gm Injection 1 while pregnant or breastfeeding?

The medicine falls under pregnancy category B - use only if needed and benefits outweigh risks. Use caution while breastfeeding as amoxicillin is excreted in breast milk. Always consult your doctor before using this medicine.

Are there any specific precautions while using E Klav 1.2gm Injection 1?

Use caution if you have hepatic dysfunction, allergies, asthma, or gastrointestinal disease, especially colitis. Also, remember to complete the full course of treatment as prescribed.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

KRISHNA NAGAR, BYE PASS CHOWK, OPPOSITE ICICI BANK, KAMANI CHOWK, YAMUNANAGAR-135001, HARYANA, INDIA

Country of origin: INDIA

References

GlaxoSmithKline. (n.d.). Prescribing information for augmentin (Amoxicillin/Clavulanate potassium). https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050575s037550597s044050725s025050726s019lbl.pdf
DailyMed - AMOXICILLIN AND CLAVULANATE POTASSIUM suspension. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=99b7f40a-06f9-4b97-8eee-8e61e5106aad
Amoxicillin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01060
Clavulanic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00766

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