Defza 12 Mg Tablet 6

Defza 12 Tablet 6

Wallace Pharmaceuticals Ltd.

Strip of 6 Units

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MRP ~~₹177.8~~

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₹29.63/Units

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Composition

Deflazacort (12 Mg)

Strength:

12 MG 1 MG 24 MG 30 MG 6 MG

Defza 12 Tablet is primarily used to manage inflammatory conditions such as rheumatoid arthritis. This medicine belongs to the group known as corticosteroids, which are renowned for their strong anti-inflammatory and immunosuppressive properties.

In addition to managing rheumatoid arthritis, this medicine is also utilised to manage bronchial asthma, various allergic conditions, and Duchenne muscular dystrophy (DMD). These additional uses arise from the medicine's ability to reduce inflammation and modify the immune system's response, which can be beneficial in these conditions.

Before you start taking this medicine, it's important to consult your doctor, who will advise on the appropriate dosage and frequency. Before starting this medicine, inform your doctor about any pre-existing diseases or ongoing medication. If you experience any side effects, notify your doctor immediately. Continue taking the medicine for the duration your doctor prescribes for optimal results.

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Defza 12 Tablet is used for the following:

Managing rheumatoid arthritis
Controlling bronchial asthma
Managing allergic conditions
Managing Duchenne muscular dystrophy (DMD), a genetic disorder that causes muscle weakness and degeneration

Here's how you should take Defza 12 Tablet:

Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
Do not miss a dose, but if you do, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule.
Don't stop taking this medicine without consulting your doctor first.

Defza 12 Tablet is taken orally.

Defza 12 Tablet may have the following common side effects:

Weight gain
Mood changes
Insomnia
Increased risk of infections
Irregular menstrual periods
Acne
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Defza 12 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Mood changes: If these become disruptive to daily life, try taking your tablet in the evening.
Gastrointestinal disturbances: Taking Defza 12 Tablet with food may help to lessen this effect.

Defza 12 Tablet contains deflazacort (12 mg), which works on your body in the following ways:

Anti-Inflammatory Action: Deflazacort reduces inflammation in the body. It achieves this by binding to glucocorticoid receptors, which in turn regulate the genes involved in the inflammatory process.
Immunosuppressive Activity: By binding to the same glucocorticoid receptors, deflazacort also suppresses the immune system. This action helps to manage autoimmune conditions where the immune system mistakenly attacks the body's tissues.

Pregnancy

Caution is advised while taking Defza 12 Tablet if you are pregnant. It's best to consult your doctor before taking this medicine.

Breastfeeding

Please check with your doctor before using Defza 12 Tablet if you are breastfeeding.

Alcohol

It's advisable to consult your doctor for guidance on alcohol consumption while on this medicine.

Liver

If you have liver health concerns, it's advised to discuss them with your doctor before starting Defza 12 Tablet.

Kidney

Caution is advised before using Defza 12 Tablet if you have a history of any kidney problems. Consulting your doctor is always a good idea before starting this medicine.

Using Machines & Driving

Defza 12 Tablet may affect your ability to drive or operate heavy machinery. Consult your doctor if you have any concerns.

Allergy

Defza 12 Tablet should not be used if you're allergic to deflazacort or any other components of the tablet. Always inform your doctor about any known allergies before starting this medication.

Children

Caution is advised while giving Defza 12 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Defza 12 Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age, consult with your doctor who will guide you based on your health status.

Drug-Drug Interactions

Defza 12 Tablet interacts with the following medicines:

NSAIDs: Medicines like ibuprofen and naproxen can interfere with the anti-inflammatory effect of Defza 12 Tablet.
Anticoagulants: Medicines such as heparin and warfarin might have their effects amplified, increasing the risk of bleeding.
Antidiabetic agents: Medications like metformin or insulin may be less effective, leading to high blood sugar levels.
Antihypertensive medications: Medicines such as losartan or amlodipine may have their blood pressure-lowering effect reduced.
Antibiotics: Specific antibiotics like erythromycin or clarithromycin can enhance the action of Defza 12 Tablet, increasing the risk of side effects.
Anticonvulsants: Medicines like phenytoin or carbamazepine can reduce the effectiveness of Defza 12 Tablet.

Drug-Food Interactions

No specific food interactions have been reported with Defza 12 Tablet.

Drug-Disease Interactions

Defza 12 Tablet interacts with the following diseases:

Diabetes: It may worsen blood sugar control in diabetic patients.
Hypertension: The medication might increase blood pressure levels.
Osteoporosis: It could increase bone loss further in osteoporosis patients.
Infections: It might worsen existing infections due to its immunosuppressive action.

Daily Dose

The dosage of Defza 12 Tablet is determined by your doctor, based on factors such as the severity of your health condition and your response to the medicine. It's crucial to adhere to the prescribed dosage without exceeding it, unless advised otherwise by your doctor.

Over Dose

An overdose of Defza 12 Tablet may lead to common symptoms like mood changes, insomnia, and gastrointestinal disturbances. If you suspect an overdose, inform your doctor to manage these symptoms appropriately.

Missed Dose

In case you miss a dose of Defza 12 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. It's not advisable to alter your dosage without consulting your doctor.

Store Defza 12 Tablet at room temperature, ideally below 30°C.
Choose a dry place, away from direct light and moisture.
Keep the medicine out of reach of children to prevent accidental ingestion.
Check the expiry date before using the product; do not use it if it expires.

If you're managing rheumatoid arthritis with Defza 12 Tablet, consider including omega-3 fatty acids in your diet. Foods like fish, walnuts, and chia seeds can help reduce inflammation.
For those managing bronchial asthma, avoid exposure to allergens such as dust and pet dander and refrain from smoking as this can worsen your condition.

Fact Box

Drug Category	Glucocorticoid
Therapeutic Category	Corticosteroid
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid arthritis, Bronchial asthma, Duchenne muscular dystrophy

What is Defza 12 Tablet used for?

Defza 12 Tablet is primarily used to manage inflammatory conditions such as rheumatoid arthritis, bronchial asthma, allergies, and Duchenne muscular dystrophy.

How does Defza 12 Tablet work?

This medicine contains deflazacort, which reduces inflammation and modifies the immune system's response, thus managing the symptoms of various conditions.

Can Defza 12 Tablet be taken with food?

You must take the medicine as directed by your doctor.

What should I do if I miss a dose of Defza 12 Tablet?

If you miss a dose, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one.

Can I stop taking Defza 12 Tablet suddenly?

No, sudden discontinuation of this medicine may lead to adrenal insufficiency. Always consult your doctor before making any changes to your medication routine.

Can Defza 12 Tablet be used during pregnancy?

Defza 12 Tablet should only be used during pregnancy if your doctor believes the benefits outweigh the potential risks to the foetus.

Are there any side effects of Defza 12 Tablet?

Common side effects include weight gain, mood changes, insomnia, and gastrointestinal disturbances. Serious side effects may include osteoporosis and hypertension, among others.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

T1/B NATIONAL PARKGULBAI TEKRA AHMEDABAD GJ 380015 IN

Country of origin: INDIA

References

Marathon Pharmaceuticals, LLC. (2017). Highlights of prescribing information. In EMFLAZA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208684s000,208685s000lbl.pdf
Deflazacort: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11921
DailyMed - EMFLAZA- deflazacort tablet EMFLAZA- deflazacort suspension. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31b347d2-f156-4055-9d8f-7cf0df420296
Deflazacort: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a617024.html

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