Combilite Cream 20 Gm

Combilite Cream 20 GM

Renova Lifesciences Pvt.ltd

Pack of 20 GM

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MRP ~~₹180~~

₹147.6

₹9.00/GM

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*MRP inclusive of all taxes

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Composition

Fluocinolone (0.01 %) + Hydroquinone (2 %) + Tretinoin (0.025 %)

Combilite Cream 20 GM is commonly used to manage melasma, a frequent skin condition featuring dark, discoloured patches on the face. It's a combination medicine that falls under the category of corticosteroids, skin-lightening agents, and retinoids.

In addition to its primary use for melasma, this is also beneficial for inhibiting melanin production and promoting skin cell turnover. These additional benefits result in an improved and even skin tone.

Before starting this medicine, it's crucial to consult your doctor who will guide you regarding the correct dosage and frequency. Make sure to inform your doctor about any pre-existing conditions or ongoing medicines you are currently taking. If you notice any side effects while using this medicine, don't hesitate to notify your doctor right away. For optimal results, continue using this cream for the duration prescribed by your doctor.

Combilite Cream 20 GM is used for the following:

Managing moderate to severe melasma on the face.
Assisting in reducing inflammation and itching in affected areas of skin.
Aiding in the fading of dark spots to even out skin tone by inhibiting melanin production.
Promoting skin cell turnover and renewal to improve skin texture.

Directions for Use of Combilite Cream 20 GM

To use Combilite Cream 20 GM effectively, follow these steps:

Gently cleanse the affected area with a mild soap before application.
Rinse the area with water and pat it dry.
Apply a thin layer of the cream to the hyperpigmented areas, preferably 30 minutes before bedtime.
Avoid applying near eyes, mouth, and mucous membranes.
After application, remember to wash your hands thoroughly.
Minimise sun exposure while using this cream. If you need to be outdoors, use sunscreen with an SPF of at least 30 and wear protective clothing like wide-brimmed hats. For any specific advice regarding its use, consult your doctor.

Combilite Cream 20 GM is applied topically.

Combilite Cream 20 GM may have the following common side effects:

Redness
Burning sensation
Stinging
Itching
Dryness
Peeling
Mild irritation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Combilite Cream 20 GM. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of guidelines for managing common side effects:

Redness: If redness occurs after applying this cream, you may want to apply it at bedtime.
Dryness: If dryness is experienced, consider applying a moisturiser in the morning, ensuring there's ample time gap between applying Combilite Cream 20 GM and the moisturiser.

Combilite Cream 20 GM is a combination of three active ingredients:

Fluocinolone (0.01%): This corticosteroid reduces inflammation and itching in the affected areas.
Hydroquinone (2%): Known as a skin-lightening agent which works by reducing melanin synthesis, which in turn helps fade dark spots and even out skin tone.
Tretinoin (0.025%): A type of retinoid that promotes skin cell turnover and renewal by exfoliating the skin, reducing the appearance of hyperpigmentation and improving skin texture.

Pregnancy

Combilite Cream 20 GM is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's vital to discuss this with your doctor before starting this medicine.

Breastfeeding

Combilite Cream 20 GM is also contraindicated for breastfeeding women. Ensure you consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol when using this medicine. It's best to consult your doctor for more information.

Liver

If you have liver problems, it's advisable to discuss them with your doctor before starting this medicine.

Kidney

Similarly, caution is advised before using Combilite Cream 20 GM if you have a history of kidney problems. Consulting your doctor before using this medicine would be a prudent step.

Using Machines & Driving

If you experience any side effects that may affect your capabilities in these areas, please consult your doctor.

Allergy

Combilite Cream 20 GM is contraindicated if you have a history of hypersensitivity to any of its ingredients, including fluocinolone acetonide, hydroquinone, tretinoin or the sulfite preservative.

Children

Caution is advised while giving Combilite Cream 20 GM to individuals under 18 years of age. Always consult a doctor before giving any medicine to a child.

Older Patients

Older patients should use Combilite Cream 20 GM under medical supervision as they might be more susceptible to its side effects. If you are above 70 years of age or have liver and kidney concerns, it's advisable to consult your doctor who will guide you based on your health status.

Drug-Drug Interactions

Combilite Cream 20 GM interacts with the following medicines:

Topical Medications: Using Combilite Cream 20 GM with other topical medications (like benzoyl peroxide, salicylic acid, or resorcinol) could lead to increased skin irritation or dryness.
Immunosuppressants: Taking immunosuppressants (like cyclosporine or tacrolimus) while using Combilite Cream 20 GM may increase the risk of infections or reduce the immune response.

Drug-Food Interactions

There are no known specific food interactions with Combilite Cream 20 GM.

Drug-Disease Interactions

Combilite Cream 20 GM interacts with the following diseases:

Hypersensitivity: If you have a history of hypersensitivity to any of the cream's components, such as fluocinolone acetonide, hydroquinone, tretinoin, or the sulfite preservative, using Combilite Cream 20 GM could cause adverse reactions.
Skin Conditions: If your skin is sunburned, windburned, dry, chapped, irritated, or if you have open wounds, using this medicine could worsen these conditions.

Daily Dose

Your doctor will prescribe the daily dose of Combilite Cream 20 GM, which could vary depending on your condition and how you respond to the treatment. It's crucial not to use more than prescribed without consulting your doctor.

Over Dose

If you accidentally apply an excessive amount of Combilite Cream 20 GM, don't panic. Rinse the area with clean water and consult your doctor if you notice any persistent or worsening symptoms.

Missed Dose

If you forget to apply Combilite Cream 20 GM at the usual time, apply it as soon as you remember. But if it's nearly time for your next application, skip this missed dose and continue with your usual schedule. Do not double up on doses without seeking advice from your doctor.

Store Combilite Cream 20 GM at room temperature.
Keep it away from extreme heat, bright light, and moisture.
Ensure the tube is tightly closed after each use.
Keep it out of reach of children.

As Combilite Cream 20 GM is used to manage melasma, it's crucial for you to minimise your exposure to sunlight. Whenever you're outside, wear a wide-brimmed hat or use an umbrella for protection.
Apply a broad-spectrum sunscreen with an SPF of at least 30 daily. This will help protect your skin from harmful UV rays that can worsen your condition.

Fact Box

Drug Category	Corticosteroid, Skin-Lightening Agent, Retinoid
Therapeutic Category	Skin Care Medicine
Available Dosage Types	Cream
Habit Forming	No
Ailment	Melasma

What is Combilite Cream 20 GM used for?

Combilite Cream 20 GM is primarily used to manage moderate to severe melasma of the face, which are dark, discoloured patches on the skin.

How does Combilite Cream 20 GM work?

Combilite Cream 20 GM contains three active ingredients that reduce inflammation, inhibit melanin production, and promote skin cell turnover, leading to a more even skin tone.

How long does it take to see results with Combilite Cream 20 GM?

You may notice improvements in your melasma within 4 to 8 weeks of consistent use of Combilite Cream 20 GM. However, complete clearing could take several months.

Can I use Combilite Cream 20 GM for a long time?

No, Combilite Cream 20 GM is intended for short-term use only. Its continuous usage over a long period is not recommended due to potential side effects.

Can I apply Combilite Cream 20 GM on other body parts apart from the face?

No, Combilite Cream 20 GM is specifically indicated for managing melasma on the face. Using it on other body parts isn't recommended as its safety and effectiveness haven't been established for those areas.

What precautions should I take while using Combilite Cream 20 GM?

Avoid sun exposure and use a broad-spectrum sunscreen daily while using Combilite Cream 20 GM. Also, avoid using other topical medications in the same area without consulting your doctor.

Are there any side effects of using Combilite Cream 20 GM?

Yes, some common side effects include redness, burning sensation, itching, dryness and peeling of skin. If these persist or worsen, consult your doctor immediately.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

35/36/37, R. K. INDUSTRIAL PARK, OPP. BHARAT BENZ SHOWROOM, OFF, NATIONAL HIGHWAY 8-B, Rampara Beti, Gujarat 360023

Country of origin: INDIA

References

U.S. National Library of Medicine. (n.d.). Fluocinolone topical. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682271.html
U.S. Food and Drug Administration. (2013). Drugs@FDA: FDA-approved drugs. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021112s006lbl.pdf
U.S. Food and Drug Administration. (2014a). Drugs@FDA: FDA-approved drugs. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021112s009lbl.pdf
U.S. National Library of Medicine. (n.d.). DailyMed: Current medication information. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/fda
Tretinoin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00755
Hydroquinone. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB09526
PubChem. (n.d.). Hydroquinone. https://pubchem.ncbi.nlm.nih.gov/compound/785

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