Cmvee 450 Mg Tablet 2

Cmvee 450 MG Tablet 2

Rpg Life Sciences Ltd.

Pack of 2 Units

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MRP ~~₹849.37~~

₹696.48

₹424.69/Units

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Composition

Valganciclovir (450 Mg)

Strength:

450 MG 350 MG

Cmvee 450 MG Tablet 2 is primarily utilised for managing cytomegalovirus (CMV) retinitis in adult patients who have acquired immunodeficiency syndrome (AIDS). This medicine falls into the category of antiviral medications.

Apart from managing CMV retinitis, it's also used to prevent CMV disease in those who have received an organ transplant from a CMV-positive donor. This medicine aids in controlling the spread of CMV infection, thereby preventing further complications.

The dosage and frequency of Cmvee 450 MG Tablet 2 should be determined by your doctor, based on factors such as your age, body weight, and overall health condition. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects, immediately notify your doctor. To achieve the best results, continue taking the medicine for the duration prescribed by your doctor.

Cmvee 450 MG Tablet 2 is used for the following:

Managing cytomegalovirus (CMV) retinitis in adults with acquired immunodeficiency syndrome (AIDS): This is a viral infection of the eye's retina that can cause vision issues and even blindness if left unchecked.
Preventing CMV disease in individuals who have received an organ transplant from a CMV-positive donor: This helps to prevent the onset of the disease in patients who have received an organ from a donor who is positive for this virus.

Directions for Use of Cmvee 450 MG Tablet 2

Here's how you should take Cmvee 450 MG Tablet 2:

Swallow the tablet whole with a full glass of water.
Don't chew, crush or break the tablet.
Consistency is key try to take this medicine at the same time each day.
Never increase your dose without consulting your doctor.

Cmvee 450 MG Tablet 2 is taken orally.

Cmvee 450 MG Tablet 2 may have the following side effects:

Fungal infection in the mouth
Headache
Shortness of breath
Abdominal pain
Loss of appetite
Nausea
Vomiting
Diarrhoea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Cmvee 450 MG Tablet 2. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's advice on managing a couple of the side effects:

Diarrhoea: Increase your water and fibre intake.
Nausea: If you're feeling nauseous, it might help to take this medicine after meals.

Cmvee 450 MG Tablet 2 contains Valganciclovir (450 mg) which works in the following ways:

Conversion to Ganciclovir: Once ingested, Valganciclovir is converted into Ganciclovir in your body. Ganciclovir is the active antiviral agent that directly fights the virus.
Inhibition of Virus Replication: Ganciclovir inhibits the multiplication of the CMV virus in your body cells. By doing so, it prevents the growth and production of new virus particles.

This dual action of Valganciclovir, first transforming into Ganciclovir and then inhibiting the virus multiplication, helps manage and control the spread of CMV infection.

Pregnancy

Caution is advised while taking Cmvee 450 MG Tablet 2 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Cmvee 450 MG Tablet 2 is contraindicated for breastfeeding women. It's important to discuss this with your doctor to understand the potential risks and benefits.

Alcohol

You should avoid consuming alcohol while on Cmvee 450 MG Tablet 2. Alcohol may interact with this medicine, potentially affecting its effectiveness or causing side effects. Please consult your doctor for more information.

Liver

Caution is advised while taking Cmvee 450 MG Tablet 2 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine. This medicine may affect liver function.

Kidney

If you have a history of kidney problems, it's good practice to consult your doctor before using the Cmvee 450 MG Tablet 2.

Using Machines & Driving

This medication may cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you.

Allergy

Cmvee 450 MG Tablet 2 is not recommended if you are allergic to valganciclovir, ganciclovir, or any inactive ingredients in the tablet. If you have known allergies, discuss them with your doctor before starting this medication.

Children

Cmvee 450 MG Tablet 2 is not intended for use in children under 18 unless prescribed by a doctor. Always consult a doctor before giving this medicine to a child.

Older Patients

Older patients should take Cmvee 450 MG Tablet 2 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70. Older patients might also have liver and kidney issues and might be on other medication. Your doctor can guide you based on your health status.

Drug-Drug Interactions

Cmvee 450 MG Tablet 2 interacts with the following medicines:

Other antivirals: Cmvee 450 MG Tablet 2 may interact with antivirals like zidovudine, potentially affecting the effectiveness of either medication.
Immunosuppressants: Medicines like mycophenolate mofetil, used to prevent organ rejection in transplant patients, may interact with Cmvee 450 MG Tablet 2, possibly leading to altered medicinal effects or increased risk of side effects.
Kidney disease medicines: Probenecid, a medicine used to treat gout and kidney stones, may interact with Cmvee 450 MG Tablet 2, potentially affecting its excretion from the body.

Drug-Food Interactions

Cmvee 450 MG Tablet 2 can be taken with or without food.

Drug-Disease Interactions

Cmvee 450 MG Tablet 2 interacts with the following diseases:

Kidney Disease: Patients with kidney problems should use caution as the dosage of Cmvee 450 MG Tablet 2 may need to be adjusted due to altered kidney function.
Liver Disease: People with liver disease should exercise caution as Cmvee 450 MG Tablet 2 could exacerbate their condition.
Blood Disorders: Patients with low blood cell counts should use caution as Cmvee 450 MG Tablet 2 can further decrease blood cell counts.

Daily Dose

The daily dose of Cmvee 450 MG Tablet 2 should be as prescribed by your doctor. This can vary based on factors such as how severe your condition is and how your body responds to the medicine. It's crucial not to exceed the prescribed dosage without discussing it with your doctor.

Over Dose

If you accidentally take more Cmvee 450 MG Tablet 2 than prescribed, you might experience common side effects like nausea or diarrhoea. If these symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you forget to take your Cmvee 450 MG Tablet 2 dose, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Store Cmvee 450 MG Tablet 2 at room temperature below 30°C.
Keep the tablet container tightly closed to guard against moisture.
Ensure the medication is stored in a place not easily accessible by children.
Always check the expiry date before taking the tablet.

If you're suffering from CMV retinitis, wearing sunglasses outdoors can protect your eyes from further damage by reducing UV exposure.
Maintain a healthy lifestyle with balanced nutrition to support your immune system. This medicine is used to manage viral infections in patients with weakened immunity.

Fact Box

Drug Category	Antiviral Prodrug
Therapeutic Category	Antiviral
Available Dosage Types	Tablet
Habit Forming	No
Ailment	CMV Retinitis, CMV Disease Prevention

What is the primary use of Cmvee 450 MG Tablet 2?

Cmvee 450 MG Tablet 2 is primarily used for managing cytomegalovirus retinitis in adults with AIDS and for preventing CMV disease post-organ transplant.

How does Cmvee 450 MG Tablet 2 work?

This medicine contains valganciclovir, which inhibits the multiplication of the CMV virus in the body, controlling the infection's spread.

Is it safe to take Cmvee 450 MG Tablet 2 during pregnancy or while breastfeeding?

Caution is advised. Consult your doctor about the potential risks and benefits of using this medication during pregnancy or breastfeeding.

Can I consume other medications while taking Cmvee 450 MG Tablet 2?

Common side effects include diarrhoea, nausea, vomiting, stomach pain, fever, headache, insomnia, and dizziness. Stay well hydrated to help manage these side effects.

How should I take my Cmvee 450 MG Tablet 2?

The tablet should be swallowed whole, preferably with or just after a meal. Do not crush or chew it.

What if I miss a dose of Cmvee 450 MG Tablet 2?

If you miss a dose, take it as soon as you remember unless it's nearly time for the next one. Don't take double doses.

Can I drive or operate machinery after taking Cmvee 450 MG Tablet 2?

If you experience dizziness or drowsiness after taking the medicine, avoid driving or lifting heavy machinery until you know how it affects you.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

RPG House, 463, Dr. Annie Besant Road, Worli, Mumbai 400030

Country of origin: INDIA

References

Highlights of prescribing information. (2001). [Prescribing information]. In Valcyte. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021304s008,022257s003lbl.pdf
Genentech. (2001). VALCYTE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/022257s009,021304s014lbl.pdf
Hoffmann-La Roche Limited. (2021). VALCYTE [Product Monograph]. In VALCYTE. https://assets.roche.com/f/173850/x/ad2abcc5b2/valcyte_pm_e.pdf
Auro Pharma Inc. (2017). PRODUCT MONOGRAPH AURO-VALGANCICLOVIR Valganciclovir Tablets 450 mg valganciclovir (as valganciclovir hydrochloride). https://pdf.hres.ca/dpd_pm/00040172.PDF
Valganciclovir: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01610

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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