Clavilip 1075 Mg Capsule 15

Clavilip 10 Capsule 15

Intas Pharmaceuticals Ltd

Pack of 10 Units
STRIP of 15 Units

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MRP ~~₹261~~

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Composition

Atorvastatin (10 Mg) + Clopidogrel (75 Mg)

Clavilip 10 Capsule is primarily used for the prevention of heart attacks, strokes, and other cardiovascular events in individuals at high risk. This medicine is a combination of two active ingredients and belongs to the class of statins and antiplatelet agents.

This medicine is also effective in managing elevated levels of total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides, while increasing HDL cholesterol in patients with primary hyperlipidemia and mixed dyslipidemia. It is also beneficial for those with a history of heart attack, stroke, or peripheral arterial disease.

Before taking this medicine, consult your doctor for the appropriate dosage and frequency. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Clavilip 10 Capsule is used for:

Lowering high total cholesterol and low-density lipoprotein (LDL) or "bad" cholesterol levels
Decreasing high levels of triglycerides and apolipoprotein B
Increasing the amount of high-density lipoprotein (HDL) or "good" cholesterol
Preventing heart attack, stroke, and vascular death in individuals with a history of these conditions
Helping protect individuals who are at high risk of cardiovascular events due to factors like diabetes, hypertension, smoking, low HDL levels, or a family history of early coronary artery disease

Directions for Use of Clavilip 10 Capsule 15

Swallow the capsule whole with a glass of water.
Avoid crushing, chewing or opening the capsule.
In case you miss a dose, take it as soon as you remember. However, if your next dose is due soon, skip the missed dose. Never take two doses at once.
Always consult your doctor for specific advice on how to take this medicine.

Clavilip 10 Capsule is taken orally.

Clavilip 10 Capsule may have the following common side effects:

Headache
Nausea
Diarrhoea
Joint, back or muscle pain
Dizziness
Rash
Nosebleeds
Drowsiness
Insomnia

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Clavilip 10 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Drowsiness: Consider taking this medicine at bedtime if it causes you sleepiness during the day.

Clavilip 10 Capsule contains two active ingredients that work together to reduce cardiovascular risk:

Atorvastatin (10 mg): This statin inhibits the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. As a result, it decreases levels of LDL ("bad") cholesterol and triglycerides, while slightly increasing levels of HDL ("good") cholesterol. Reducing LDL cholesterol lessens the risk of atherosclerosis, thereby preventing heart attacks and strokes.
Clopidogrel (75 mg): This antiplatelet agent works by irreversibly inhibiting the P2Y12 component of ADP receptors on platelets, preventing their activation and aggregation. By preventing clot formation, it reduces the risk of harmful blood clots that can lead to heart attacks and strokes. Clopidogrel is a prodrug, which means it needs to be metabolised by enzymes in the liver to become active.

Pregnancy

Caution is advised while taking Clavilip 10 Capsule if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's important to discuss with your doctor before starting Clavilip 10 Capsule.

Alcohol

To ensure the effectiveness of Clavilip 10 Capsule, it is recommended to limit alcohol consumption during the course of this medicine.

Liver

If you have liver problems, please discuss them with your doctor before starting Clavilip 10 Capsule. This medicine may affect liver function.

Kidney

Exercise caution while taking Clavilip 10 Capsule if you have any kidney problems. Consultation with your doctor is advised before commencing this medicine.

Using Machines & Driving

Clavilip 10 Capsule may cause drowsiness or dizziness. Please avoid driving or operating heavy machinery if you experience these symptoms.

Allergy

If you're allergic to atorvastatin or clopidogrel, do not take Clavilip 10 Capsule. Always share your medical history, especially of allergies, with your doctor before starting any medication.

Children

Clavilip 10 Capsule should only be given to children under strict medical supervision. It's always better to consult a paediatrician first.

Older Patients

Older patients should take Clavilip 10 Capsule under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Clavilip 10 Capsule interacts with the following medicines:

Cholesterol-lowering medicines: If you are taking other cholesterol-lowering medications such as fibrates or niacin, your doctor should be informed. These can interact with Clavilip 10 Capsule and alter its effectiveness.
Blood thinners: Medications like warfarin have a potential interaction risk with Clavilip 10 Capsule, leading to an increased chance of bleeding.
HIV protease inhibitors: Ritonavir, an HIV protease inhibitor can increase the blood levels of atorvastatin present in Clavilip 10 Capsule, leading to an amplified effect.
Antifungals: Oral antifungals like itraconazole may also interact with this medication, causing increased blood levels of atorvastatin.
Immunosuppressants: Cyclosporine used for organ transplant patients can interact with Clavilip 10 Capsule, increasing the risk of side effects.
Oral contraceptives: Clopidogrel present in Clavilip 10 Capsule might interact with oral contraceptives leading to altered medicinal effects.

Drug-Food Interactions

Grapefruit and grapefruit juice should be avoided while taking Clavilip 10 Capsule as they can increase the levels and effects of atorvastatin.

Drug-Disease Interactions

Clavilip 10 Capsule interacts with the following diseases:

Liver disease: Patients with liver disease should exercise caution while taking this medicine as it may exacerbate their condition.
Diabetes: The medication could impact blood sugar control, making it essential to monitor glucose levels closely when on this medicine.
Upcoming surgery or dental procedures: Due to its clot-preventing properties, it is advised to stop the intake of Clavilip 10 Capsule at least 5-7 days prior to any surgery or dental procedures to avoid excessive bleeding.

Daily Dose

The daily dose of Clavilip 10 Capsule should be taken as directed by your doctor. Your dosage may change based on factors such as the severity of your condition and how you respond to the medication. It's crucial to stick to your prescribed dosage and not increase it without consulting your doctor.

Over Dose

Exceeding the prescribed dose of Clavilip 10 Capsule could lead to side effects like nausea, headaches, and muscle pain. If you've taken more than your recommended dose, speak to your doctor, especially if these symptoms persist or worsen.

Missed Dose

If you forget to take your Clavilip 10 Capsule, do so as soon as you remember. However, if it's nearly time for your next dose, skip the dose you missed and continue with your regular schedule. Don't increase your dosage without speaking to your doctor.

Store Clavilip 10 Capsule in a tightly sealed container, at room temperature, ideally below 30°C.
Make sure the medicine is kept away from direct light and moisture.
Always ensure this medication is out of reach of children.
Use the medicine before its expiry date.

As Clavilip 10 Capsule is used to manage heart conditions, keeping a watch on your diet can help. Opt for foods low in saturated fats and high in fibre to maintain healthy cholesterol levels.
Regular physical activity can also benefit your heart. Ensure you fit in at least 30 minutes of moderate-intensity exercise most days of the week. Remember to consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	HMG-CoA Reductase Inhibitor, Antiplatelet Agent
Therapeutic Category	Lipid-Lowering Medicine
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Heart Attack, Stroke, Hyperlipidemia

What is Clavilip 10 Capsule used for?

Clavilip 10 Capsule is used to reduce the risk of heart attacks, strokes and other cardiovascular events in patients with high-risk factors.

How does Clavilip 10 Capsule work?

It contains atorvastatin, which reduces bad cholesterol, and clopidogrel that prevents harmful blood clots, both helping in managing cardiovascular risks.

How should I take Clavilip 10 Capsule?

The medicine is taken orally. It can be swallowed whole with water, either with or without food.

What should I do if I miss a dose of Clavilip 10 Capsule?

If you miss a dose, take it as soon as you remember. If it's almost time for the next dose, skip the missed one.

Are there any side effects of Clavilip 10 Capsule?

Common side effects may include headache, nausea, diarrhoea and muscle pain. Serious but rare side effects like severe muscle pain need immediate doctor consultation.

Is there anyone who shouldn't use Clavilip 10 Capsule?

Yes, people allergic to atorvastatin or clopidogrel, or having active liver disease or persistent elevated liver enzymes shouldn't use this medicine.

Can I take other medicines while using Clavilip 10 Capsule?

Clavilip 10 Capsule can interact with certain medicines. Always provide your doctor with a full list of all medicines you're taking before starting this medication.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

Pfizer. (1996). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020702s073lbl.pdf
Atorvastatin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01076
Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership. (1997). PLAVIX (clopidogrel bisulfate) tablets, for oral use [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020839s062s064lbl.pdf
Clopidogrel: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00758

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