Certican 05 Mg Tablet 10

Certican 0.5 Tablet 10

Novartis India Ltd

Strip of 10 Units

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MRP ~~₹1821.53~~

₹1639.38

₹182.15/Units

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Composition

Everolimus (0.5 Mg)

Strength:

0.5 MG 0.75 MG 0.25 MG

Certican 0.5 Tablet is primarily used to prevent organ rejection in adults who have undergone kidney, heart, or liver transplantation. It is also used in the treatment of cancer. It belongs to a class of medicines known as immunosuppressants.

In addition to its main use, the medicine may also be used to manage conditions where the immune system needs to be suppressed, such as certain autoimmune diseases.

Consult your doctor for the correct dosage and frequency of this medicine. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor promptly. It's important to continue taking the medicine for the duration prescribed by your doctor for best results.

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Certican 0.5 Tablet is used for the following:

Preventing organ rejection after a kidney transplant
Reducing the risk of organ rejection following a heart transplant
Lowering the chance of your body rejecting a transplanted liver
Managing Certain Types of Tumors and cancers

Directions for Use of Certican 0.5 Tablet 10

Follow these steps while taking Certican 0.5 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Take this medicine with or without food.
Always consult your doctor before changing your dose.

Certican 0.5 Tablet is taken orally.

Certican 0.5 Tablet may have the following common side effects:

Constipation
Headache
Nausea
Mouth sores: Small, painful ulcers that appear in your mouth.
Infections

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing Certican 0.5 Tablet. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.

Here is how you can manage some common side effects:

Constipation: Increasing your intake of fluids and dietary fibre can aid in easing this symptom.
Nausea: Try taking your Certican 0.5 Tablet after meals to reduce nausea.

Certican 0.5 Tablet contains Everolimus (0.5 mg). Here's how it works:

Inhibits T and B cells: Everolimus acts by inhibiting the activation and proliferation of T cells and B cells. These are key components of the immune system involved in organ rejection.
Suppresses Immune Response: By inhibiting these immune cells, Everolimus effectively suppresses the body's immune response, thus preventing the body from attacking and rejecting the transplanted organ.

Pregnancy

Certican 0.5 Tablet should only be taken during pregnancy if the potential benefit outweighs the risk to the unborn child. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Certican 0.5 Tablet if breastfeeding. It is a good idea to consult your doctor before taking this medicine.

Alcohol

Caution is advised before drinking while taking Certican 0.5 Tablet. Consult your doctor about any concerns related to alcohol consumption.

Liver

Caution is advised while taking Certican 0.5 Tablet in case of liver problems. If you have liver health issues, discuss them with your doctor before starting this medicine.

Kidney

Certican 0.5 Tablet is primarily used for patients who have undergone a kidney transplant; however, caution is advised if you have other existing kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

Certican 0.5 Tablet can cause fatigue, which can affect your ability to operate machinery or drive safely. If you feel unwell or experience side effects that could affect these activities, consult your doctor.

Allergy

Certican 0.5 Tablet is contraindicated in patients with known allergy to everolimus or any of its ingredients. Discuss any known allergies with your doctor before starting this medicine.

Children

Certican 0.5 Tablet is not typically prescribed for children under 18 years old. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Certican 0.5 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age.

Drug-Drug Interactions

Certican 0.5 Tablet interacts with the following medicines:

Antifungals: Medicines like ketoconazole and itraconazole can increase the levels of everolimus in your blood, enhancing its effects and potentially leading to side effects.
Antibiotics: Medications such as rifampin can decrease the levels of everolimus in your blood, reducing its effectiveness.

Drug-Food Interactions

Certican 0.5 Tablet interacts with the following foods:

Grapefruit and Grapefruit Juice: Consuming grapefruit or grapefruit juice while taking Certican 0.5 Tablet might increase the risk of side effects because they can increase the levels of everolimus in your blood.

Drug-Disease Interactions

Certican 0.5 Tablet interacts with the following diseases:

Pre-existing Infections: If you have an ongoing infection, taking Certican 0.5 Tablet might worsen your condition due to its immune-suppressing properties.
Diabetes: Certican 0.5 Tablet may affect blood sugar control, requiring close monitoring of glucose levels.
Hyperlipidaemia: Patients with high cholesterol or triglyceride levels should be cautious as this medicine might further elevate lipids.

Daily Dose

Certican 0.5 Tablet should be taken as directed by your doctor. The dosage may vary depending on your health condition and your response to the medicine. It's crucial to stick to the prescribed dosage and not alter it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Certican 0.5 Tablet, it can result in symptoms like constipation, headache, nausea, and mouth sores. If you've taken an extra dose by mistake, it's important to inform your doctor.

Missed Dose

If you forget to take Certican 0.5 Tablet, take it as soon as you remember unless it's nearly time for your next dose. In that case, skip the missed dose and carry on with your usual schedule. Do not increase the dosage without consulting your doctor.

Store Certican 0.5 Tablet at room temperature, ideally below 30°C.
Always keep it in the original package to shield it from light and moisture.
Keep this medicine out of sight and reach of children.
Use Certican 0.5 Tablet before its expiration date as mentioned on the label.

Monitor your protein intake: Excess protein can strain the kidneys. Follow a balanced diet as advised by your doctor.
Drink plenty of water to support kidney function and reduce the risk of dehydration, which can worsen certain side effects of Certican 0.5 Tablet.

Fact Box

Drug Category	mTOR Inhibitor
Therapeutic Category	Immunosuppressant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Organ Rejection Prevention

What is Certican 0.5 Tablet used for?

Certican 0.5 Tablet is primarily used to prevent organ rejection in adults who have had kidney, heart, or liver transplants. It is also used in the treatment of cancer.

How does Certican 0.5 Tablet work?

Certican 0.5 Tablet contains everolimus, which suppresses the immune system's response, reducing the likelihood of your body rejecting the new organ.

Can I take Certican 0.5 Tablet with food?

Yes, you can take this medicine with or without food, but ensure you take it regularly.

Does Certican 0.5 Tablet have any side effects?

Common side effects include constipation, headache, nausea, and mouth sores. Always consult your doctor if you experience them.

Are there any foods or beverages I should avoid while taking Certican 0.5 Tablet?

You should avoid grapefruit and grapefruit juice as they might increase the risk of adverse effects.

Can I take other medications while on Certican 0.5 Tablet?

Certain medications like antifungals can affect how Certican 0.5 Tablet works. Always inform your doctor about any new medicine you start taking.

How should I store my Certican 0.5 Tablets?

Store them at room temperature, away from light and moisture, within their original packaging.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

The Inspire BKC Part 601 & 701 Bandra Kurla Complex Bandra(E) Mumbai - India

Country of origin: SWITZERLAND

References

Novartis Pharmaceuticals Corporation. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. In AFINITOR. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022334s6lbl.pdf
Novartis Pharmaceuticals Corporation. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.novartis.com/us-en/sites/novartis_us/files/afinitor.pdf
DailyMed - EVEROLIMUS tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5aaf2fb7-93f6-40d6-941a-9583a3794ce7
Everolimus: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01590

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