Carbotero 150 Mg Injection 15 Ml

Carbotero 150 MG Injection 15 ML

Hetero Healthcare Ltd

Pack of 15 ML

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MRP ~~₹811~~

₹665.02

₹54.07/ML

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Composition

Carboplatin (150 Mg)

Carbotero 150 MG Injection 15 ML is primarily used to manage lung cancer, specifically small-cell lung cancer. This medicine is part of a class of medications known as anticancer agents.

Apart from managing lung cancer, it is also used for the management of ovarian cancer. Depending on the condition, your doctor may suggest using it for other types of cancer as well.

Before starting this medicine, you should consult your doctor who will guide you about the right dosage and frequency. It's very important to inform your doctor about any pre-existing conditions or ongoing medicines that you are currently taking. If you notice any side effects while on this medication, notify your doctor immediately. Remember to continue taking this injection for the duration prescribed by your doctor.

Uses of Carbotero 150 MG Injection 15 ML

Carbotero 150 MG Injection 15 ML is used for:

Managing small-cell lung cancer
Initial treatment of advanced ovarian cancer
Palliative management of ovarian cancer recurring after prior chemotherapy

Directions for Use of Carbotero 150 MG Injection 15 ML

Carbotero 150 MG Injection 15 ML is administered following these steps:

The medicine should be administered only under the supervision of a skilled healthcare professional, experienced in the use of anticancer medications.
The injection is given intravenously (into a vein) for 15 to 60 minutes.
Ensure proper hydration before and after the administration to minimise kidney-related side effects.
Remember, your specific dosage and treatment duration will be decided by your doctor based on your body size, general condition, and the type of cancer being managed.

Carbotero 150 MG Injection 15 ML is administered intravenously.

Side Effects of Carbotero 150 MG Injection 15 ML

Carbotero 150 MG Injection 15 ML may lead to the following side effects:

Nausea and vomiting
Hypersensitivity reactions: These are allergic responses, which can include skin rashes or itching.
Myelosuppression: This is a decrease in the production of blood cells, leading to lower counts of platelets, and red and white blood cells.
Peripheral neuropathy: This refers to damage to the nerves in your extremities, such as hands and feet, causing numbness or tingling sensations.
Elevated levels of blood urea nitrogen and serum creatinine: These are signs of impaired kidney function.
Electrolyte abnormalities: These could be low levels of sodium, magnesium, potassium or calcium in your blood.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Carbotero 150 MG Injection 15 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and Vomiting: Try taking Carbotero 150 MG Injection 15 ML after meals to help reduce these feelings.
Peripheral Neuropathy: If you experience numbness or tingling in your extremities after administering this medicine, consider adequate rest.

How Carbotero 150 MG Injection 15 ML Works?

Carbotero 150 MG Injection 15 ML contains carboplatin (150 mg), which acts in the body as follows:

Forms Reactive Platinum Complexes: Carboplatin forms reactive platinum complexes within cancer cells. These complexes bind with DNA in the cells and cause cross-linking.
Disrupts DNA Synthesis: The cross-linked DNA can't function properly. This disruption stops the synthesis of new DNA in these cells.
Causes Cell Death: As a result of the disrupted DNA synthesis, the rapidly dividing cancer cells can't grow and reproduce, leading to cell death.

Pregnancy

Carbotero 150 MG Injection 15 ML can potentially harm the foetus. If you are pregnant or planning to conceive, you should consult your doctor before starting this medication.

Breastfeeding

Breastfeeding is not recommended whilst using this medicine.

Alcohol

It's best to discuss your alcohol consumption with your doctor before starting this medicine.

Liver

If you have liver health issues, caution is advised while taking Carbotero 150 MG Injection 15 ML. This medicine may affect liver function and it is best to consult your doctor before taking it.

Kidney

Caution is advised when using Carbotero 150 MG Injection 15 ML if you have kidney problems. This medicine requires dose adjustment in patients with impaired renal function.

Using Machines & Driving

Carbotero 150 MG Injection 15 ML can cause visual disturbances, which may affect your ability to drive or operate machinery. Be cautious and consult your doctor if you experience any such symptoms.

Allergy

Do not use Carbotero 150 MG Injection 15 ML if you have had severe allergic reactions to carboplatin or other platinum-containing compounds in the past.

Children

It may not be safe to give Carbotero 150 MG Injection 15 ML in children. Always consult a doctor before giving this medication to a child.

Older Patients

Elderly patients may be more susceptible to the side effects of Carbotero 150 MG Injection 15 ML, particularly blood cell count decreases and kidney problems. Older patients should take this medicine under medical supervision.

Interactions of Carbotero 150 MG Injection 15 ML

Drug-Drug Interactions

Carbotero 150 MG Injection 15 ML interacts with the following medicines:

Aminoglycoside Antibiotics: When administered with Carbotero 150 MG Injection 15 ML, these antibiotics, such as gentamicin or tobramycin, can enhance the harmful effects on the kidneys and ears.
Loop Diuretics: Medicines like furosemide or bumetanide can intensify harmful effects on the kidneys and ears when combined with Carbotero 150 MG Injection 15 ML.
Myelosuppressive Medications: Taking medicines that lower blood cell production, such as methotrexate or azathioprine, alongside Carbotero 150 MG Injection 15 ML could lead to an increased risk of blood-related side effects.
Anticonvulsants: The effectiveness of Carbotero 150 MG Injection 15 ML can be reduced by anticonvulsants like phenytoin or carbamazepine due to their effect on carboplatin levels in your system.

Drug-Food Interactions

Carbotero 150 MG Injection 15 ML does not have any known interactions with specific foods.

Drug-Disease Interactions

Carbotero 150 MG Injection 15 ML interacts with the following diseases:

Severe Myelosuppression: If you have this condition, which is characterised by a decrease in blood cell production, Carbotero 150 MG Injection 15 ML could exacerbate your symptoms.
Severe Renal Impairment: Those with severe kidney failure should avoid using Carbotero 150 MG Injection 15 ML due to its potential for further damaging the kidneys.
Bleeding Disorders or Active Bleeding: If you suffer from these conditions, using Carbotero 150 MG Injection 15 ML could worsen bleeding issues.

Dosage of Carbotero 150 MG Injection 15 ML

Daily Dose

Your doctor will prescribe the daily dose of Carbotero 150 MG Injection 15 ML based on your health condition and response to the medication. It's vital to stick to this prescribed dosage and not alter it without consulting your doctor. For additional details, you can refer to the package insert.

Over Dose

An overdose is highly unlikely for this medication as it is administered by a skilled healthcare professional.

Missed Dose

If you forget to get a dose of Carbotero 150 MG Injection 15 ML as scheduled, consult with your doctor for advice.

Store Carbotero 150 MG Injection 15 ML vials in a cool, dry place.
Shield the product from exposure to light.
Keep it out of reach and sight of children.
Always check the expiration date before using the medicine

If you're managing small cell lung cancer with Carbotero 150 MG Injection 15 ML, consider adopting a high-protein diet to help your body repair cells and tissues.
For those dealing with ovarian cancer, aim for a diet rich in fruits and vegetables, which are packed with antioxidants that may help fight against cancer. Make sure to consult your doctor before making any significant dietary changes.

Fact Box

Drug Category	Alkylating Agent
Therapeutic Category	Anti-cancer
Available Dosage Types	Injection
Habit Forming	No
Ailment	Small Cell Lung Cancer, Ovarian Cancer

What is Carbotero 150 MG Injection 15 ML used for?

It's used to manage certain types of lung and ovarian cancers. This may extend to other cancers as determined by a doctor.

How does Carbotero 150 MG Injection 15 ML work?

It works by forming reactive substances that interfere with the cancer cell's DNA, preventing it from multiplying, and leading to cell death.

How is Carbotero 150 MG Injection 15 ML administered?

It is given as an intravenous infusion, usually over 15-60 minutes. Doctors experienced in cancer management supervise its administration.

What are some common side effects of Carbotero 150 MG Injection 15 ML?

Yes, it may cause nausea, vomiting, hair loss, and potentially serious effects on blood cells and kidneys. Regular monitoring is vital.

Can anyone use Carbotero 150 MG Injection 15 ML?

No, it's not suitable for people with severe allergies to carboplatin or platinum compounds, severe blood disorders, or significant kidney problems.

Can I take other medicines with Carbotero 150 MG Injection 15 ML?

Medicines aminoglycoside antibiotics, and loop diuretics can interact with Carbotero 150 MG Injection 15 ML. Always consult your doctor before starting or stopping any other medicine.

Is Carbotero 150 MG Injection 15 ML safe during pregnancy or breastfeeding?

It may harm the fetus if used during pregnancy and it's unknown whether it passes into breast milk. Avoid use in these situations.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

A-201/202/B-201, Dipti Classic, 32/34, W.T. Suren Rd, Andheri East, Mumbai, Maharashtra 400093

Country of origin: INDIA

References

Teva Parenteral Medicines, Inc. (2011). Patient information CARBOplatin injection. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/077139Orig1s016lbl.pdf
Eugia Pharma Inc. (2023). PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION: CARBOplatin injection. https://pdf.hres.ca/dpd_pm/00069530.PDF
Thirumaran, R., Prendergast, G. C., & Gilman, P. B. (2007). Cytotoxic chemotherapy in clinical treatment of cancer. In Elsevier eBooks (pp. 101–116). https://doi.org/10.1016/b978-012372551-6/50071-7
Carboplatin. (2007, October 1). Cancer.gov. https://www.cancer.gov/about-cancer/treatment/drugs/carboplatin
Carboplatin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00958

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