Here are the common side effects of Amlovas 5 tablet:
- Peripheral Oedema: Peripheral oedema is one of the most common side effects of Amlovas tablets. It is generally mild to moderate in severity and tends to resolve with continued treatment or dosage adjustment. Swelling of the extremities, such as ankles and feet, can occur due to the vasodilatory effect of Amlovas tablet.
- Dizziness: Some individuals may experience dizziness while taking an Amlovas tablet. Dizziness is generally mild and transient. It is primarily due to the blood pressure-lowering effects of the medication.
- Headache: Headaches are a typical side effect of Amlovas tablets. However, the incidence is relatively low and typically mild in nature.
- Flushing: Flushing, characterised by a sensation of warmth and redness of the skin, may occur due to the vasodilatory effect of Amlovas tablet. It is usually temporary and not a cause for concern.
- Fatigue: Fatigue or tiredness has been reported in some individuals taking Amlovas 5 mg tablets.
- Abdominal Pain: Occasional abdominal pain or discomfort occurrences have been documented as rare adverse effects linked with Amlovas tablet. These occurrences are generally mild in intensity and short-lived.
- Palpitations (fast heartbeat): Amlovas tablet has the potential to cause palpitations, characterised by sensations of a rapid or irregular heartbeat. Although this side effect is infrequent, individuals experiencing severe or persistent palpitations should seek medical guidance.
Managing the Side Effects
Home remedies to manage common side effects of Amlovas 5 mg Tablets are:
- Peripheral Edema: Elevate the affected limbs to reduce swelling. Refrain from standing or sitting for long periods; take regular breaks to move around. Limit salt intake to help reduce fluid retention.
- Dizziness: Sit or lie down when feeling dizzy to prevent falls. Avoid sudden changes in position, such as getting up quickly. To promote overall well-being, keeping your body hydrated and following a balanced diet is essential.
- Headache: Rest in a quiet, dark room and apply a cold or warm compress on the forehead. Meditation or deep breathing practices can be beneficial for relaxation and alleviating discomfort. Stay hydrated and maintain regular sleep patterns.
- Flushing: Stay in a relaxed environment and dress in light, breathable clothing. Use a fan or cool cloth on the face to alleviate symptoms. Avoid triggers such as spicy foods, alcohol, or hot beverages.
- Fatigue: Ensure you are getting enough sleep and maintain a consistent sleep schedule. Eat a well-balanced diet and stay hydrated. Engage in regular exercise to boost energy levels.
- Abdominal Pain: Instead of eating big meals, eat smaller, more regular meals. Avoid consuming foods that are known to potentially cause stomach pain, such as spicy or fatty foods. For momentary relief, use a heating pad or warm compress on the abdomen.
- Palpitations: Incorporate relaxation techniques like deep breathing or meditation into your routine. Limiting your caffeine intake from beverages such as coffee, tea, or energy drinks is advisable. If you experience severe or persistent palpitations, it is recommended to consult a doctor for further evaluation and guidance.
Precautions
Pregnancy
It is essential to be cautious when using Amlovas tablets during pregnancy because animal studies have suggested possible risks to the unborn baby. Before considering this medication during pregnancy, you should talk with your healthcare provider to understand the potential benefits and risks.
Breastfeeding
Amlodipine, the active ingredient in Amlovas 5 tablet, can be excreted in breast milk. It is essential to consult with a doctor before using this medication while breastfeeding to assess the potential risks to the nursing infant and consider suitable alternatives if needed.
Alcohol
Alcohol can increase the blood pressure-lowering effects of Amlodipine and may increase the risk of side effects. It is generally advised to avoid or limit alcohol intake while using an Amlovas tablet. It is recommended to consult a doctor for individualised guidance regarding alcohol consumption while taking Amlovas 5 mg tablet.
Liver
Amlovas 5 mg tablet should be used carefully by patients with liver disorders. Amlodipine is primarily metabolised in the liver, and decreased liver function may hinder its elimination from the body. Any pre-existing liver issues should be disclosed to your healthcare physician.
Kidney
Patients with kidney disease should use Amlovas tablets cautiously. Amlodipine is generally removed from the body through the kidneys, and decreased renal function can influence its clearance. Dosage modifications may be required, and kidney function should be monitored regularly. It is crucial to inform your doctor about any pre-existing kidney conditions you may have.
Using Machine and Driving
Amlovas 5 mg tablet may cause dizziness or drowsiness in some individuals. If you suffer from these side effects, it is essential to exercise caution while operating machinery or driving a vehicle.
Allergy
If you have a known allergy or hypersensitivity to Amlodipine or any other components of Amlovas 5 mg tablet, it is essential to avoid using it.
Use In Children
Amlovas 5 mg tablet, is not typically recommended for children under the age of six. The safety and effectiveness of Amlodipine in this age group have not been established. A healthcare professional should determine the dosage for children older than six years based on their specific conditions and needs.
Use In Older Patients
Elderly patients may be more susceptible to the blood pressure-lowering effects of Amlodipine. Close monitoring is necessary, and dosage adjustments may be required based on individual response and renal function.
Interaction
Drug-Drug Interactions
Amlovas 5 mg tablet can interact with medications, including.
- Antifungal Medicines: Medications such as Ketoconazole, Itraconazole can increase the concentration of Amlovas 5 mg tablet in the blood, leading to an increased risk of side effects. Close monitoring and possible dosage adjustments of Amlodipine may be necessary when used with these antifungal medicines.
- Protease Inhibitors: Simultaneous use of these HIV medications, such as Ritonavir, Indinavir, and Nelfinavir, with Amlodipine, can increase the concentration of Amlovas 5 mg tablet, potentially leading to an increased risk of side effects. Dose adjustments or alternative antihypertensive medications may be considered.
- Antibiotics: These antibiotics like Rifampicin, Erythromycin and Clarithromycin can interact with Amlodipine and alter its concentration in the blood. Rifampicin may reduce the effectiveness of Amlodipine, while erythromycin and clarithromycin can increase its concentration. Monitoring of blood pressure may be necessary.
- Heart Medicines: Combining Amlodipine with these heart medicines, Verapamil and Diltiazem, may lead to additive blood pressure-lowering effects. It is recommended to closely monitor your blood pressure when using Amlovas 5 mg tablet and adjust the dosage as necessary.
- Medicines affecting the immune system: Medications like Tacrolimus, Sirolimus, Temsirolimus, and Everolimus, can interact with Amlodipine and increase the risk of adverse effects. Close monitoring is advised when using them with Amlodipine.
- Simvastatin (Cholesterol Lowering Medicine): Simvastatin can increase the concentration of Amlodipine, potentially leading to an increased risk of side effects.
- Cyclosporine (Immunosuppressant): Cyclosporine, when consumed along with Amlodipine, potentially increases the risk of adverse effects.
- St. John's Wort (Hypericum perforatum): St. John's Wort can lower the concentration of Amlodipine in the blood, reducing its effectiveness. Avoid simultaneous use or discuss with your healthcare provider for alternative options.
Drug-Food Interactions
Amlovas 5 mg tablet can interact with foods, including:
- Multivitamin supplements: Taking Amlovas 5 mg tablet together with a multivitamin supplement containing calcium can reduce the effectiveness of the medicine. It is essential to consult your doctor before using both medications together.
Drug-Disease Interactions
Amlovas 5 mg tablet can interact with diseases, including:
- Hypotension (low blood pressure): Amlovas 5 mg tablet can cause a decrease in blood pressure. It should be used with care in patients with hypotension or conditions that may lead to low blood pressure, like heart failure or severe aortic stenosis.
- Heart failure: Amlovas 5 mg tablet is generally safe for heart failure patients. However, it should be initiated at a low dose and carefully monitored, as it can potentially worsen heart failure symptoms in some individuals.
- Liver disease: Amlovas 5 mg tablet is primarily metabolised in the liver. Patients with liver disease may have impaired clearance of the medication, which could lead to higher blood levels and an increased risk of toxicity. Close monitoring and dosage adjustments may be necessary for these individuals.
- Coronary artery disease: Amlovas 5 mg tablet, is commonly used to treat coronary artery disease. It aids in relaxing and widening the blood vessels, improving blood flow to the heart. It is essential to adhere to your doctor's recommendations and continue any other medications prescribed for your heart condition.